Alzheimer's Disease Is Associated With A High Blood Pressure

Alzheimer's Disease Is Associated With A High Blood Pressure.
People agony from cardiovascular plague who have lower-than-normal blood pressure may face a higher jeopardize of brain atrophy - the death of brain cells or connections between brain cells, Dutch researchers news June 2013. Such brain atrophy can lead to Alzheimer's infection or dementia in these patients. In contrast, similar patients with high blood pressure can tame brain atrophy by lowering their blood pressure, the researchers added.

Blood pressure is measured using two readings. The choicest number, called systolic pressure, gauges the pressure of blood poignant through arteries. The bottom number, called diastolic pressure, measures the pressure in the arteries between heartbeats. Normal blood crushing for adults is less than 120/80, according to the US National Heart, Lung, and Blood Institute.

For the study, 70 to 90 was considered conformist diastolic blood pressure, while under 70 was considered low. "Our material might suggest that patients with cardiovascular disease represent a subgroup within the universal population in whom low diastolic blood pressure might be harmful," said researcher Dr Majon Muller, an epidemiologist and geriatrician at VU University Medical Center in Amsterdam.

On the other hand, lowering blood turn the heat on in populate with high blood pressure might slow brain atrophy, she said. "Our findings could mean that blood pressure lowering is beneficial in patients with higher blood coerce levels, but one should be cautious with further blood pressure lowering in patients who already have low diastolic blood pressure," Muller added.

The boom was published in the June 10 online issue of JAMA Neurology. A US expert noted the complex effects of blood constraint levels on the brain. "High blood pressure has been shown to increase the risk of vascular brain lesions and wisdom atrophy. Trials of blood pressure lowering in patients with hypertension have shown reduced jeopardy of brain lesions," said Dr Gregg Fonarow, a professor of cardiology at the University of California, Los Angeles, and a spokesman for the American Heart Association.

However, in patients with hypertension, the relation between the levels of systolic and diastolic blood twist and brain atrophy has been less clear, he said. This unusual study suggests that low diastolic blood pressure levels were associated with brain atrophy in any event of blood pressure levels after patients developed dementia, Fonarow said. "These findings suggest that while healing and control of high blood pressure is very important for brain and cardiovascular health, forewarn is needed in patients who have low diastolic blood pressure levels," he said.

To endure what changes blood pressure would make in the progression of brain atrophy, Muller's group well-thought-out 663 patients who suffered from heart disease, cardiovascular disease, peripheral artery ailment or abdominal aortic aneurysm. The average age of participants was 57 and most were men. People whose diastolic blood apply pressure was below 70 had more brain atrophy over time, the study found.

For men and women with higher-than-normal blood pressure, brain atrophy decreased when their blood pressure did. When blood tension rose, however, atrophy increased. Another expert, Dr Sam Gandy, affiliate director of the Mount Sinai Alzheimer's Disease Research Center in New York City, said that the conclusion "is an important cautionary tale".

This implies that one must qualify the approach to the individual patient. Correction of hypertension is helpful, but reducing blood pressure in patients with general blood pressure is risky and complicated," Gandy said keepskincare.com. Although the study found an pairing between low diastolic blood pressure and the risk of developing brain atrophy for people with artery disease, it did not create a cause-and-effect relationship.