Sunday 29 September 2013

The Use Of Nicotinic Acid In The Treatment Of Heart Disease

The Use Of Nicotinic Acid In The Treatment Of Heart Disease.
Combining the vitamin niacin with a cholesterol-lowering statin dull appears to suggest patients no gain and may also lengthen side effects, a new library indicates. It's a disappointing result from the largest-ever study of niacin for spunk patients, which involved almost 26000 people effects. In the study, patients who added the B-vitamin to the statin hypnotic Zocor saying no added benefit in terms of reductions in heart-related death, non-fatal pluck attack, stroke, or the need for angioplasty or ignore surgeries.

The study also found that people taking niacin had more incidents of bleeding and (or) infections than those who were intriguing an inactive placebo, according to a troupe reporting Saturday at the annual meeting of the American College of Cardiology, in San Francisco. "We are defeated that these results did not show benefits for our patients," exploration lead author Jane Armitage, a professor at the University of Oxford in England, said in a assembly telecast release. "Niacin has been used for many years in the belief that it would help patients and taboo heart attacks and stroke, but we now know that its adverse affectation effects outweigh the benefits when used with current treatments".

Niacin has hanker been used to boost levels of "good" HDL cholesterol and curtailment levels of "bad" LDL cholesterol and triglycerides (fats) in the blood in common people at risk for heart disease and stroke. However, niacin also causes a numeral of side effects, including flushing of the skin. A medicine called laropiprant can lose weight the incidence of flushing in people taking niacin. This unknown study included patients with narrowing of the arteries.

They received either 2 grams of extended-release niacin benefit 40 milligrams of laropiprant or analogous placebos. All of the patients also took Zocor (simvastatin). The patients from China, the United Kingdom and Scandinavia were followed for an mediocre of almost four years.

Saturday 21 September 2013

Some Hope For A Vaccine Against The Advanced Stages Of Cancer

Some Hope For A Vaccine Against The Advanced Stages Of Cancer.
Scientists have genetically tweaked an virus to the latest a salutary vaccine that appears to dissolve a disparity of advanced cancers. The vaccine has provoked the required tumor-fighting insusceptible response in early human trials, but only in a minority of patients tested. and one whiz urged caution. "They were able to develop an immune response with the vaccine bowtrolcoloncleanse.drug-purchase.info. That's a actual thing but we need a little more information," said Dr Adam Cohen, aide professor in medical oncology at Fox Chase Cancer Center in Philadelphia.

He was not knotty in the study. "This is the senior study in cancer patients with this type of vaccine, with a less small number of patients treated so far," Cohen noted. "So while the untouched response data are promising, further swot in a larger number of patients will be required to assess the clinical improve of the vaccine".

One vaccine to treat prostate cancer, Provenge, was recently approved by the US Food and Drug Administration. However, Cohen famed that many other cancer vaccines have shown primitive compact and not panned out.

The theory behind therapeutic cancer vaccines is that race with cancer tend to have defects in their immune system that compromise their wit to respond to malignancy, explained study lead writer Dr Michael Morse, associate professor of cure-all at Duke University Medical Center. "A vaccine has to achievement by activating immune cells that are capable of killing tumors and those protected cells have to survive long enough to get to the tumor and destroy it," he explained.

Thursday 19 September 2013

Ethnic And Racial Differences Were Found In The Levels Of Biomarkers C-Reactive Protein In The Blood

Ethnic And Racial Differences Were Found In The Levels Of Biomarkers C-Reactive Protein In The Blood.
Levels of the blood biomarker C-reactive protein (CRP) can fluctuate all manifold ethnological and ethnic groups, which might be a vital in determining heart-disease risk and the value of cholesterol-lowering drugs, a imaginative British study suggests fav store net. CRP is a trade mark of inflammation, and elevated levels have been linked - but not proven - to an increased gamble for heart disease.

Cholesterol-lowering drugs called statins can humble heart risk and CRP, but it's not wholly if lowering levels of CRP helps to adjust heart-disease risk. "The difference in CRP between populations was sufficiently big-hearted as to influence how many people from different populations would be considered at strong risk of heart attack based on an isolated CRP weight and would also affect the proportion of people eligible for statin treatment," said survey researcher Aroon D Hingorani, a professor of genetic epidemiology and British Heart Foundation Senior Research Fellow at University College London. "The results of the flow look call they physicians should bear ethnicity in belief in interpreting the CRP value," she added.

The report is published in the Sept 28, 2010 online printing of Circulation: Cardiovascular Genetics. For the study, Hingorani and her colleagues reviewed 89 studies that included more than 221000 people. They found that CRP levels differed by line and ethnicity, with blacks having the highest levels at an mediocre of 2,6 milligrams per liter (mg/L) of blood. Hispanics were next (2,51 mg/L), followed by South Asians (2,34 mg/L), whites (2,03 mg/L), and East Asians (1,01 mg/L).

Monday 16 September 2013

A Strict Diet Improves The Condition Of The Patient In The First Year After Diagnosis Of Diabetes

A Strict Diet Improves The Condition Of The Patient In The First Year After Diagnosis Of Diabetes.
Dietary changes solitary can raise the white flag the same benefits as changes in both sustenance and utilization in the firstly year after a person is diagnosed with type 2 diabetes, a green study contends. English researchers found that patients who were encouraged to forfeit weight by modifying their diet with the help of a dietician had the same improvements in blood sugar (glycemic) control, pressure loss, cholesterol and triglyceride levels as those who changed both their legislature and physical job levels as 30 minutes of brisk walking five times a week prescription. Both groups achieved about a 10 percent upgrading in blood sugar control, cholesterol and triglyceride levels compared to patients who received tedious care.

The two intervention groups also disoriented an ordinary of 4 percent of their body weight, while those in a performance care group had little or no weight loss. Patients in the bit care group were also three times more likely than those in the intervention groups to create on diabetes medication before the end of the study.

And "Getting populace to exercise is quite difficult, and can be expensive," lead researcher Rob Andrews, a elder lecturer at the University of Bristol, said in an American Diabetes Association scoop release. "What this con tells us is that if you only have a limited amount of money, in that first year of diagnosis, you should pinpoint on getting the diet right".

He pointed out, however, that the bookwork participants with type 2 diabetes preferred to promise in both exercise and dietary changes. "They found diet simply quite negative," he said. One reason they might not have seen an additional promote from exercise, he added, "is because people often make a trade. That is, if they go to the gym, then they take oneself to be as if they can have a treat. That could be why we commonplace no difference in the weight loss for the diet plus exercise group".

Saturday 14 September 2013

Too Early To Talk About An Epidemic Of Dengue Fever In The United States

Too Early To Talk About An Epidemic Of Dengue Fever In The United States.
Two more cases of dengue fever were reported by vigour officials in Florida this week, bringing the unqualified to 46 confirmed cases since mould September, but a superb ministry healthfulness official said it's too early to say whether the mosquito-borne tropical blight is gaining a foothold in the United States. "We don't have knowledge of how dengue got to Key West, and whether or not it's endemic," said Harold Margolis, head of the dengue diversify of the US Centers for Disease Control and Prevention, in San Juan, PR fav store net. "It's only prevalent to play out as we watch to see what happens during this warm, saturated period of time, which is when dengue is at its peak," he added.

And "That's the enigma with a disease like this," Margolis said. "You have to care for it but, at the same time, you also have to try to oversee it". The most common virus transmitted by mosquitoes, dengue causes up to 100 million infections and 25000 deaths worldwide each year. The ailment is found mostly in tropical climates, and many parts of the world, including Central and South America and the Caribbean, are currently experiencing epidemics.

In Puerto Rico, for instance, there have been at least five deaths and more than 6000 suspected cases of dengue this year. Margolis said it's practical that the Florida outbreak is an anomalous incident. "We've seen this happen in other parts of the world, such as in northern Australia, where travelers replace with the infection and bring out dengue, it spreads for a era of time, and then it goes away," he said.

In the United States, a smattering of locally acquired cases in Texas have been reported since 1980, and all of them have coincided with liberal outbreaks in neighboring Mexican cities. The termination dengue outbreak in Florida was 75 years ago, according to the CDC.

The infirmity typically causes flu-like symptoms such as tipsy fever, headache, and achy muscles, bones and joints. Symptoms typically begin about two to seven days after being bitten. "It's also called breakbone fever, because some mortals get surely horrible, exacting pains in their bones and joints," explained Dr Bert Lopansri, medical commander of the Loyola University Health System International Medicine and Traveler's Immunization Clinic, in Maywood, Ill. There is no marinate or vaccine, and in most cases the disease resolves on its own within a yoke of weeks.

Friday 13 September 2013

The Link Between Recurrent Miscarriages And The Risk Of Heart Attacks In Women

The Link Between Recurrent Miscarriages And The Risk Of Heart Attacks In Women.
Women who deteriorate repetitious miscarriages have a greatly increased jeopardize of guts attack later in life, finds a supplementary study. Researchers analyzed data from more than 11500 women who had been fruitful at least once and found that 25 percent had experienced at least one detectable miscarriage, 18 percent had had at least one abortion and 2 percent had trained a stillbirth. Over a bolstering of about 10 years, 82 of the women had a consideration attack and 112 had a stroke howporstarsgrowit.com. There was no significant fellowship between any type of pregnancy loss and stroke, said the researchers.

Each breakdown increased heart attack risk by 40 percent, and having more than two miscarriages increased the chance by more than fourfold. Women who had more than three miscarriages had a ninefold increased risk. The study, published online Dec 1, 2010 in the list Heart, also found that having at least one stillbirth increased the gamble of enthusiasm devour 3,5 times.

The degree of risk associated with persistent miscarriage decreased when the researchers factored in major pith attack factors such as smoking, weight and alcohol consumption, but the imperil was still five times higher than normal. "These results suggest that women who competent spontaneous pregnancy loss are at a substantially higher endanger of heart attack later in life," the researchers wrote in a scandal release from the publisher. "Recurrent miscarriage and stillbirth are staunch gender predictors for this and thus should be considered as important indicators for monitoring cardiovascular hazard factors and preventive measures," they said.

Tuesday 10 September 2013

The Device That Avoids Open Heart Surgery With Artificial Valve Does Not Work

The Device That Avoids Open Heart Surgery With Artificial Valve Does Not Work.
If an concocted ticker valve derived from a cow or pig fails to composition properly, researchers mean implanting a automated valve inside the artificial valve could be an option for high-risk patients keepskincare.com. "Once expanded and opened, the unripe valve opens and functions similarly to the patient's own valve.

The upper hand is that sans surgical valves can be replaced without the need for open-heart surgery," over lead author Dr John G Webb, medical helmsman of Interventional Cardiology and Interventional Research at St Paul's Hospital in Vancouver, Canada, explained in an Ameruican Heart Association story release. Webb and colleagues on on 24 high-risk patients who underwent surgery that transplanted a additional meretricious valve into the existing artificial one.

The valves were inserted through a catheter - either via a insignificant gash between the ribs, or through a leg blood vessel - and expanded with the employee of balloons that pushed the old valves away. The design isn't appropriate in all cases. Still, "patients may rally more rapidly, and the concerns about major surgery are reduced," Webb said. The researchers appear that the traditional treatment - a redone open-heart operation - is very risky. The reading was reported April 12 in the journal Circulation.

Heart Valve Diseases, also called: Valvular pith disease. Your heart has four valves. Normally, these valves bounteous to let blood surge through or out of your heart, and then shut to keep it from flowing backward. But once in a while they don't work properly.

Wednesday 4 September 2013

Drinking Increasing Among Girls And Young Women In The USA

Drinking Increasing Among Girls And Young Women In The USA.
Binge drinking is a significant disturbed amid women and girls in the United States, with one in five female high-priced form students and one in eight young women reporting around at episodes, federal health officials reported Tuesday. For women, binge drinking means downing four or more drinks on an occasion aldara. Every month, about 14 million women and girls binge toss off at least three times, according to the arrive from the US Centers for Disease Control and Prevention (CDC).

And women who binge liquid refreshment commonplace about six drinks at a time, the statement said. "Although binge drinking is even more of a difficulty amidst men and boys, binge drinking is an urgent and unrecognized women's health issue," CDC director Dr Thomas Frieden, said during a midday press conference. And the consequences for women, who proceeding alcohol differently than men, are serious, Frieden said. "There are about 23000 deaths amongst women and girls each year due to drinking too much alcohol," he said. "Most of those deaths are from binge drinking".

Binge drinking also increases the endanger for many salubriousness problems such as heart cancer, sexually transmitted diseases, pith disease and unintended pregnancy, he added. In addition, with child women who binge drink expose their infant to high levels of alcohol that can lead to fetal alcohol spectrum disorders and unexpected infant death syndrome, he noted.

Frieden famous that the number of adult women who binge drink hasn't changed much in the career 15 years. But changing patterns all young people mean that high school girls are binge drinking nearly as often as boys, Frieden explained. "While the be entitled to to each high school boys fell considerably in new decades, it has remained relatively constant among towering school girls, which is why there is hardly any difference at this point between boys and girls in drinking," he said.

Sunday 1 September 2013

The Use Of Triple Antiretroviral Drugs During Feeding Protects The Child From HIV

The Use Of Triple Antiretroviral Drugs During Feeding Protects The Child From HIV.
In sub-Saharan Africa, many mothers with HIV are faced with an horrendous choice: breast-feed their babies and peril infecting them or use formula, which is often out of across to because of set or can sick the baby due to a lack of clean drinking water acaiberry. Now, two strange studies acquire that giving pregnant and nursing women triple antiretroviral drug therapy, or treating breast-fed infants with an antiretroviral medication, can dramatically prepare dispatch rates, enabling moms to both breast-feed and to take under one's wing nearly all children from infection.

In one study, a combination antiretroviral drug psychoanalysis given to pregnant and breast-feeding women in Botswana kept all but 1 percent of babies from contracting the infection during six months of breast-feeding. Without the narcotize therapy, about 25 percent of babies would become infected with the AIDS-causing virus, according to researchers from the Harvard School of Public Health.

A flash study, led by researchers from the University of North Carolina at Chapel Hill, found that giving babies an antiretroviral narcotic once a time during their anything else six months of soul reduced the transmission dress down to 1,7 percent. Both studies are published in the June 17 progeny of the New England Journal of Medicine.

In the United States, HIV-positive women are typically given antiretrovirals during pregnancy to elude disappearance HIV to their babies in utero or during labor and delivery. After the infant is born, women are advised to use formula as an alternative of breast-feeding for the same reason, said senior study author Dr Charles M van der Horst, a professor of medicament and contagious diseases at the University of North Carolina at Chapel Hill.

That guts well in developed nations where formula is easy to come by and a good water supply is readily available, van der Horst said. But throughout much of sub-Saharan Africa, soak supplies can be contaminated by bacteria and other pathogens that, especially in the scantiness of good medical care, can cause diarrheal illnesses that can be implacable for babies.

Previous investigate has shown that formula-fed babies in the region die at a high rate from pneumonia or diarrheal disease, leaving women in a Catch-22. "In Africa, boob bleed is absolutely essential for the first six months of life," van der Horst said. "Mothers there have knowledge of that. It was a 'between a sway and a hard place' copy for them".