Many Women In The First Year After Menopause Deteriorating Memory And Fine Motor Skills.
Women growing through menopause occasionally give the impression they are off their mental game, forgetting phone numbers and passwords, or struggling to find a particular word. It can be frustrating, baffling and worrisome, but a small new study helps to explain the struggle. Researchers found that women in the initially year after menopause perform slightly worse on certain mentally ill tests than do those who are approaching their post-reproductive years. "This study shows, as have others, that there are cognitive cognitive declines that are real, statistically significant and clinically significant," said study author Miriam Weber, an helpmeet professor in the department of neurology at the University of Rochester in Rochester, NY "These are remote declines in performance, so women aren't becoming globally impaired and unable to function. But you cognizance it on a daily basis".
The study is published in the current issue of the journal Menopause. According to the researchers, the technique of learning, retaining and applying new information is associated with regions of the discernment that are rich in estrogen receptors. The natural fluctuation of the hormone estrogen during menopause seems to be linked to problems associated with ratiocinative and memory. "We found the problem is not related to absolute hormone levels. Estrogen declines in the transition, but before it falls, there are theatrical fluctuations".
Weber explained that it is the variation in estrogen constant that most likely plays a critical role in creating the memory problems many women experience. As the body readjusts to the changes in hormonal levels on a future occasion after a woman's period stops, the researchers shady mental challenges diminish. While Weber said it is important that women gather from that memory issues associated with menopause are most likely normal and temporary, the study did not include women whose periods had stopped for longer than one year. Weber added that she plans to pinpoint more exactly how long-term recollection and thinking problems persist in a future study.
Other research has offered conflicting conclusions about the rational changes associated with menopause, the study authors wrote. The Chicago spot of the Study of Women's Health Across the Nation (SWAN) initially found no relation between what stage of menopause women were in and how they performed on tests of working homage or perceptual speed. However, a different SWAN mull over identified deficits in memory and processing speed in the late menopausal stage.
Studies of menopause typically characterize distinct stages of menopause, although researchers may differ in where they draw the line between those transitions. The researchers tortuous with this study said that the variation in findings between studies may be due to different ways of staging menopause.
Thursday 23 January 2020
Wednesday 22 January 2020
The Use Of Steroids For The Treatment Of Spinal Stenosis
The Use Of Steroids For The Treatment Of Spinal Stenosis.
Older adults who get steroid injections for degeneration in their put down spinal column may fare worse than woman in the street who skip the treatment, a small study suggests. The research, published recently in the chronicle Spine, followed 276 older adults with spinal stenosis in the lower back. In spinal stenosis, the raise spaces in the spinal column gradually narrow, which can put pressure on nerves. The important symptoms are pain or cramping in the legs or buttocks, especially when you walk or stand for a crave period.
The treatments range from "conservative" options like anti-inflammatory painkillers and physical psychotherapy to surgery. People often try steroid injections before resorting to surgery. Steroids calm inflammation, and injecting them into the room around constricted nerves may ease pain - at least temporarily. In the unexplored study, researchers found that patients who got steroid injections did see some pain relief over four years.
But they did not diet as well as patients who went with other conservative treatments or with surgery right away. And if steroid patients ultimately opted for surgery, they did not improve as much as surgery patients who'd skipped the steroids.
It's not shiny why, said lead researcher Dr Kris Radcliff, a spine surgeon with the Rothman Institute at Thomas Jefferson University, in Philadelphia. "I deem we need to face at the results with some caution". Some of the study patients were randomly assigned to get steroid injections, but others were not - they opted for the treatment. So it's accomplishable that there's something else about those patients that explains their worse outcomes.
On the other workman steroid injections themselves might hamper healing in the long run. One likelihood is that injecting the materials into an already cramped space in the spine might make the situation worse, once the endorse pain-relieving effects of the steroids wear off. "But that's just our speculation".
A pain brass specialist not involved in the work said it's impossible to pin the blame on epidural steroids based on this study. For one, it wasn't a randomized clinical trial, where all patients were assigned to have steroid injections or not have them, said Dr Steven Cohen, a professor at Johns Hopkins School of Medicine, in Baltimore. The patients who opted for epidural steroids "may have had more difficult-to-treat pain, or a worse pathology".
Older adults who get steroid injections for degeneration in their put down spinal column may fare worse than woman in the street who skip the treatment, a small study suggests. The research, published recently in the chronicle Spine, followed 276 older adults with spinal stenosis in the lower back. In spinal stenosis, the raise spaces in the spinal column gradually narrow, which can put pressure on nerves. The important symptoms are pain or cramping in the legs or buttocks, especially when you walk or stand for a crave period.
The treatments range from "conservative" options like anti-inflammatory painkillers and physical psychotherapy to surgery. People often try steroid injections before resorting to surgery. Steroids calm inflammation, and injecting them into the room around constricted nerves may ease pain - at least temporarily. In the unexplored study, researchers found that patients who got steroid injections did see some pain relief over four years.
But they did not diet as well as patients who went with other conservative treatments or with surgery right away. And if steroid patients ultimately opted for surgery, they did not improve as much as surgery patients who'd skipped the steroids.
It's not shiny why, said lead researcher Dr Kris Radcliff, a spine surgeon with the Rothman Institute at Thomas Jefferson University, in Philadelphia. "I deem we need to face at the results with some caution". Some of the study patients were randomly assigned to get steroid injections, but others were not - they opted for the treatment. So it's accomplishable that there's something else about those patients that explains their worse outcomes.
On the other workman steroid injections themselves might hamper healing in the long run. One likelihood is that injecting the materials into an already cramped space in the spine might make the situation worse, once the endorse pain-relieving effects of the steroids wear off. "But that's just our speculation".
A pain brass specialist not involved in the work said it's impossible to pin the blame on epidural steroids based on this study. For one, it wasn't a randomized clinical trial, where all patients were assigned to have steroid injections or not have them, said Dr Steven Cohen, a professor at Johns Hopkins School of Medicine, in Baltimore. The patients who opted for epidural steroids "may have had more difficult-to-treat pain, or a worse pathology".
Smoking And Weight Gain Increases The Death Rate From Prostate Cancer
Smoking And Weight Gain Increases The Death Rate From Prostate Cancer.
Men treated for prostate cancer who smoke or put on glut pounds amass their discrepancy of disease recurrence and of dying from the illness, two new studies show. The findings were presented Tuesday at the American Association for Cancer Research's annual conclave in Washington, DC.
In the fundamental report, a team led by Dr Jing Ma, an associate professor of pharmaceutical at Brigham and Women's Hospital in Boston, found that obesity and smoking may not be risk factors for developing prostate cancer, but they do augmentation the odds that a man who has the illness will die from it. Being overcast and smoking "predispose men to a significantly high risk of cancer-specific and all-cause mortality," Ma said during a Tuesday matinal news conference.
"Compared to lean non-smokers, obese smokers had the highest jeopardy of prostate cancer mortality". For the study, Ma's team collected data on more than 2700 men with prostate cancer who took role in the Physicians Health Study. Over 27 years of follow-up, 882 of the men died, 11 percent from the cancer.
The researchers found that both avoirdupois move further and smoking boosted the risk for dying from the cancer. In fact, every five-point flourish in body mass index (BMI) increased the risk for dying from prostate cancer by 52 percent. BMI is a assessment of height versus weight, with the threshold of overweight set at a BMI of 25 and the sill for obesity set at a BMI of 30.
In addition, men who smoked increased their risk for dying from the cancer by 55 percent, compared with men who never smoked, the muse about found. "These data underscore the lack for implementing effective preventive strategies for weight control and reducing tobacco use in both fit men as well as prostate cancer patients".
In a second report, a team led by Corinne E Joshu, a postdoctoral colleague in the department of epidemiology at Johns Hopkins Bloomberg School of Public Health, found that men who gained preponderance after having their prostate removed were almost twice as likely to discover their cancer return as were men who maintained their weight. "Weight gain may increase the risk of prostate cancer recurrence after prostatectomy," Joshu said during the AACR advice conference.
"Obesity, especially among serene men, may also contribute to the risk of prostate cancer recurrence". For the study, Joshu's crew collected data on more than 1300 men with localized prostate cancer who underwent prostatectomy between 1993 and 2006. In addition, the men completed a examine on diet, lifestyle and other factors such as weight, zenith and physical activity five years before surgery and again one year after the procedure.
Men treated for prostate cancer who smoke or put on glut pounds amass their discrepancy of disease recurrence and of dying from the illness, two new studies show. The findings were presented Tuesday at the American Association for Cancer Research's annual conclave in Washington, DC.
In the fundamental report, a team led by Dr Jing Ma, an associate professor of pharmaceutical at Brigham and Women's Hospital in Boston, found that obesity and smoking may not be risk factors for developing prostate cancer, but they do augmentation the odds that a man who has the illness will die from it. Being overcast and smoking "predispose men to a significantly high risk of cancer-specific and all-cause mortality," Ma said during a Tuesday matinal news conference.
"Compared to lean non-smokers, obese smokers had the highest jeopardy of prostate cancer mortality". For the study, Ma's team collected data on more than 2700 men with prostate cancer who took role in the Physicians Health Study. Over 27 years of follow-up, 882 of the men died, 11 percent from the cancer.
The researchers found that both avoirdupois move further and smoking boosted the risk for dying from the cancer. In fact, every five-point flourish in body mass index (BMI) increased the risk for dying from prostate cancer by 52 percent. BMI is a assessment of height versus weight, with the threshold of overweight set at a BMI of 25 and the sill for obesity set at a BMI of 30.
In addition, men who smoked increased their risk for dying from the cancer by 55 percent, compared with men who never smoked, the muse about found. "These data underscore the lack for implementing effective preventive strategies for weight control and reducing tobacco use in both fit men as well as prostate cancer patients".
In a second report, a team led by Corinne E Joshu, a postdoctoral colleague in the department of epidemiology at Johns Hopkins Bloomberg School of Public Health, found that men who gained preponderance after having their prostate removed were almost twice as likely to discover their cancer return as were men who maintained their weight. "Weight gain may increase the risk of prostate cancer recurrence after prostatectomy," Joshu said during the AACR advice conference.
"Obesity, especially among serene men, may also contribute to the risk of prostate cancer recurrence". For the study, Joshu's crew collected data on more than 1300 men with localized prostate cancer who underwent prostatectomy between 1993 and 2006. In addition, the men completed a examine on diet, lifestyle and other factors such as weight, zenith and physical activity five years before surgery and again one year after the procedure.
Researchers Warn About The Harmful Influence Of TV
Researchers Warn About The Harmful Influence Of TV.
A imaginative scrutiny suggests that immersing yourself in news of a shocking and tragic event may not be good for your affective health. People who watched, read and listened to the most coverage of the Boston Marathon bombings - six or more hours quotidian - reported the most acute stress levels over the following weeks. Their symptoms were worse than kinsmen who had been directly exposed to the bombings, either by being there or knowing someone who was there.
Those exposed to the media coverage typically reported around 10 more symptoms - such as re-experiencing the blow and compassion stressed out thinking about it - after the results were adjusted to account for other factors. The study authors phrase the findings should raise more concern about the effects of graphic news coverage. The scrutinize comes with caveats. It's not clear if watching so much coverage directly caused the stress, or if those who were most troubled share something in common that makes them more vulnerable.
Nor is it known whether the stress affected people's true health. Still, the findings offer insight into the triggers for stress and its potential to linger, said inquiry author E Alison Holman, an associate professor of nursing science at the University of California, Irvine. "If proletariat are more stressed out, that has an impact on every part of our life. But not everybody under the sun has those kinds of reactions.
It's important to understand that variation". Holman, who studies how people become stressed, has worked on preceding research that linked acute stress after the 9/11 attacks to later resolution disease in people who hadn't shown signs of it before. Her research has also linked watching the 9/11 attacks palpable to a higher rate of later physical problems. In the new study, researchers old an Internet survey to ask questions of 846 Boston residents, 941 New York City residents and 2888 society from the rest of the country.
A imaginative scrutiny suggests that immersing yourself in news of a shocking and tragic event may not be good for your affective health. People who watched, read and listened to the most coverage of the Boston Marathon bombings - six or more hours quotidian - reported the most acute stress levels over the following weeks. Their symptoms were worse than kinsmen who had been directly exposed to the bombings, either by being there or knowing someone who was there.
Those exposed to the media coverage typically reported around 10 more symptoms - such as re-experiencing the blow and compassion stressed out thinking about it - after the results were adjusted to account for other factors. The study authors phrase the findings should raise more concern about the effects of graphic news coverage. The scrutinize comes with caveats. It's not clear if watching so much coverage directly caused the stress, or if those who were most troubled share something in common that makes them more vulnerable.
Nor is it known whether the stress affected people's true health. Still, the findings offer insight into the triggers for stress and its potential to linger, said inquiry author E Alison Holman, an associate professor of nursing science at the University of California, Irvine. "If proletariat are more stressed out, that has an impact on every part of our life. But not everybody under the sun has those kinds of reactions.
It's important to understand that variation". Holman, who studies how people become stressed, has worked on preceding research that linked acute stress after the 9/11 attacks to later resolution disease in people who hadn't shown signs of it before. Her research has also linked watching the 9/11 attacks palpable to a higher rate of later physical problems. In the new study, researchers old an Internet survey to ask questions of 846 Boston residents, 941 New York City residents and 2888 society from the rest of the country.
US Experts Have Established Reasons Of Decrease In The Pregnancy Rate
US Experts Have Established Reasons Of Decrease In The Pregnancy Rate.
Pregnancy rates pursue to weakening in the United States, a federal make public released Dec 2013 shows. The rate reached a 12-year low in 2009, when there were about 102 pregnancies for every 1000 women age-old 15 to 44, according to the latest statistics from the US Centers for Disease Control and Prevention. That be worthy of is 12 percent below the 1990 be entitled to of about 116 pregnancies per 1000 women.
Only the 1997 rate of 102 has been lower during the since 30 years, according to the report. Experts said two factors are driving the downward trend: improved access to descent control and decisions by women to put off childbearing until later in life. Those trends have caused the ordinary age of pregnancy to shift upward. Pregnancy rates for teenagers also have reached celebrated lows that extend across all racial and ethnic groups.
Between 1990 and 2009, the pregnancy gauge fell 51 percent for white and black teenagers, and 40 percent for Hispanic teenagers. The teen origin rate dropped 39 percent between 1991 and 2009, and the teen abortion gait decreased by half during the same period. Overall, pregnancy rates have continued to diminish for women younger than 30. "The amount of knowledge that young women have about their family control options is very different compared to a few decades ago," said Dr Margaret Appleton, manager of the division of obstetrics and gynecology at the Scott andamp; White Clinic in College Station, Texas.
Pregnancy rates pursue to weakening in the United States, a federal make public released Dec 2013 shows. The rate reached a 12-year low in 2009, when there were about 102 pregnancies for every 1000 women age-old 15 to 44, according to the latest statistics from the US Centers for Disease Control and Prevention. That be worthy of is 12 percent below the 1990 be entitled to of about 116 pregnancies per 1000 women.
Only the 1997 rate of 102 has been lower during the since 30 years, according to the report. Experts said two factors are driving the downward trend: improved access to descent control and decisions by women to put off childbearing until later in life. Those trends have caused the ordinary age of pregnancy to shift upward. Pregnancy rates for teenagers also have reached celebrated lows that extend across all racial and ethnic groups.
Between 1990 and 2009, the pregnancy gauge fell 51 percent for white and black teenagers, and 40 percent for Hispanic teenagers. The teen origin rate dropped 39 percent between 1991 and 2009, and the teen abortion gait decreased by half during the same period. Overall, pregnancy rates have continued to diminish for women younger than 30. "The amount of knowledge that young women have about their family control options is very different compared to a few decades ago," said Dr Margaret Appleton, manager of the division of obstetrics and gynecology at the Scott andamp; White Clinic in College Station, Texas.
Scientists Are Researching The Causes Of The Inability To Read
Scientists Are Researching The Causes Of The Inability To Read.
Glitches in the connections between unfailing acumen areas may be at the root of the common learning hubbub dyslexia, a new study suggests. It's estimated that up to 15 percent of the US citizens has dyslexia, which impairs people's ability to read. While it has long been considered a brain-based disorder, scientists have not conceded exactly what the issue is.
The new findings, reported in the Dec 6, 2013 circulation of Science, suggest the blame lies in faulty connections between the brain's storage spell for speech sounds and the brain regions that process language. The results were surprising, said be conducive to researcher Bart Boets, because his team expected to find a different problem. For more than 40 years many scientists have meditation that dyslexia involves defects in the brain's "phonetic representations" - which refers to how the central sounds of your native language are categorized in the brain.
But using sensitive perception imaging techniques, Boets and colleagues found that was not the case in 23 dyslexic adults they studied. The phonetic representations in their brains were just as "intact" as those of 22 adults with regular reading skills. Instead, it seemed that in citizenry with dyslexia, language-processing areas of the brain had difficulty accessing those phonetic representations. "A apt metaphor might be the comparison with a computer network," said Boets, of the Leuven Autism Research Consortium in Belgium.
And "We show that the data - the data - on the server itself is intact, but the correlation to access this information is too slow or degraded". And what does that all mean? It's too soon to tell, said Boets. First of all this studio used one form of brain imaging to study a small conglomeration of adult university students. But dyslexia normally begins in childhood.
Glitches in the connections between unfailing acumen areas may be at the root of the common learning hubbub dyslexia, a new study suggests. It's estimated that up to 15 percent of the US citizens has dyslexia, which impairs people's ability to read. While it has long been considered a brain-based disorder, scientists have not conceded exactly what the issue is.
The new findings, reported in the Dec 6, 2013 circulation of Science, suggest the blame lies in faulty connections between the brain's storage spell for speech sounds and the brain regions that process language. The results were surprising, said be conducive to researcher Bart Boets, because his team expected to find a different problem. For more than 40 years many scientists have meditation that dyslexia involves defects in the brain's "phonetic representations" - which refers to how the central sounds of your native language are categorized in the brain.
But using sensitive perception imaging techniques, Boets and colleagues found that was not the case in 23 dyslexic adults they studied. The phonetic representations in their brains were just as "intact" as those of 22 adults with regular reading skills. Instead, it seemed that in citizenry with dyslexia, language-processing areas of the brain had difficulty accessing those phonetic representations. "A apt metaphor might be the comparison with a computer network," said Boets, of the Leuven Autism Research Consortium in Belgium.
And "We show that the data - the data - on the server itself is intact, but the correlation to access this information is too slow or degraded". And what does that all mean? It's too soon to tell, said Boets. First of all this studio used one form of brain imaging to study a small conglomeration of adult university students. But dyslexia normally begins in childhood.
Tuesday 21 January 2020
FDA Will Strengthen The Supervision Of Used Home Medical Equipment
FDA Will Strengthen The Supervision Of Used Home Medical Equipment.
As the citizenry ages and medical technology improves, more subjects are using complex medical devices such as dialysis machines and ventilators at home, adding to the requisite for better-educated patients. To join this growing need, the US Food and Drug Administration announced Tuesday that it has started a unfamiliar program to ensure that patients and their caregivers use these devices safely and effectively.
So "Medical gubbins home use is becoming an increasingly important public health issue," Dr Jeffrey Shuren, chief of the FDA's Center for Devices and Radiological Health said during an afternoon news conference. The US populace is aging, and more people are living longer with chronic diseases that demand home care. "In addition, more patients of all ages are being discharged from the hospital to continue their supervision at home".
Meanwhile, medical devices have become more portable and sophisticated, making it possible to treat and monitor long-lived conditions outside the hospital. "A significant number of devices including infusion pumps, ventilators and mortification care therapies are now being used for home care".
Given the growing number of home medical devices, the intervention plans on developing procedures for makers of home-care equipment. Procedures will incorporate post-marketing follow-up, and other things that will encourage the safe use of these devices. The FDA is also developing eye-opening materials on the safe use of these devices, the agency said.
As the citizenry ages and medical technology improves, more subjects are using complex medical devices such as dialysis machines and ventilators at home, adding to the requisite for better-educated patients. To join this growing need, the US Food and Drug Administration announced Tuesday that it has started a unfamiliar program to ensure that patients and their caregivers use these devices safely and effectively.
So "Medical gubbins home use is becoming an increasingly important public health issue," Dr Jeffrey Shuren, chief of the FDA's Center for Devices and Radiological Health said during an afternoon news conference. The US populace is aging, and more people are living longer with chronic diseases that demand home care. "In addition, more patients of all ages are being discharged from the hospital to continue their supervision at home".
Meanwhile, medical devices have become more portable and sophisticated, making it possible to treat and monitor long-lived conditions outside the hospital. "A significant number of devices including infusion pumps, ventilators and mortification care therapies are now being used for home care".
Given the growing number of home medical devices, the intervention plans on developing procedures for makers of home-care equipment. Procedures will incorporate post-marketing follow-up, and other things that will encourage the safe use of these devices. The FDA is also developing eye-opening materials on the safe use of these devices, the agency said.
Useless The Second Phase Of The Definition Of Brain Death
Useless The Second Phase Of The Definition Of Brain Death.
Making families time for a second-best exam to confirm a brain death diagnosis is not only supererogatory but may make it less likely that the family will agree to donate their loved one's organs, a unexplored study finds. Researchers reviewed records from the New York Organ Donor Network database of 1,229 adults and 82 children who had been declared cognition dead. All of the ancestors had died in New York hospitals over a 19-month period between June 2007 and December 2009.
Patients had to lacuna an average of nearly 20 hours between the first and second exam, even though the New York State Health Department recommends a six-hour wait, according to the study. Not only did the tick exam continue nothing to the diagnosis - not one patient was found to have regained brain function between the first and the second exam - verbose waiting times appeared to make families more reluctant to give consent for organ donation. About 23 percent of families refused to grant their loved ones organs, a include that rose to 36 percent when wait times stretched to more than 40 hours, the investigators found.
The gossip was also true: Consent for organ donation decreased from 57 percent to 45 percent as hold on times were dragged out. Though the research did not look at the causes of the refusal, for families, waiting around for a next exam means another emotionally exhausting, stressful and uncertain day waiting in an exhaustive care unit to find out if it's time to remove their loved one from life support, said inspect author Dr Dana Lustbader, chief of palliative care at The North Shore LIJ Health System in Manhasset, NY.
At the same time, the patient's already shaky ready can further decrease the odds of organ donation occurring as waiting times go up. Organ viability decreases the longer a soul is brain dead.
Making families time for a second-best exam to confirm a brain death diagnosis is not only supererogatory but may make it less likely that the family will agree to donate their loved one's organs, a unexplored study finds. Researchers reviewed records from the New York Organ Donor Network database of 1,229 adults and 82 children who had been declared cognition dead. All of the ancestors had died in New York hospitals over a 19-month period between June 2007 and December 2009.
Patients had to lacuna an average of nearly 20 hours between the first and second exam, even though the New York State Health Department recommends a six-hour wait, according to the study. Not only did the tick exam continue nothing to the diagnosis - not one patient was found to have regained brain function between the first and the second exam - verbose waiting times appeared to make families more reluctant to give consent for organ donation. About 23 percent of families refused to grant their loved ones organs, a include that rose to 36 percent when wait times stretched to more than 40 hours, the investigators found.
The gossip was also true: Consent for organ donation decreased from 57 percent to 45 percent as hold on times were dragged out. Though the research did not look at the causes of the refusal, for families, waiting around for a next exam means another emotionally exhausting, stressful and uncertain day waiting in an exhaustive care unit to find out if it's time to remove their loved one from life support, said inspect author Dr Dana Lustbader, chief of palliative care at The North Shore LIJ Health System in Manhasset, NY.
At the same time, the patient's already shaky ready can further decrease the odds of organ donation occurring as waiting times go up. Organ viability decreases the longer a soul is brain dead.
The Flu Vaccine Is Little Effect On Men
The Flu Vaccine Is Little Effect On Men.
The flu vaccine is less impressive for men than women, and researchers at Stanford University suppose they've figured out why. The manly hormone testosterone causes genes in the immune arrangement to produce fewer antibodies, or defense mechanisms, in response to the vaccine, they found. "Men, typically, do worse than women in vaccinated response to infection and vaccination," said Stanford research affiliate David Furman, the lead study investigator.
For instance, men are more susceptible to bacterial, viral, fungal and parasitic infection than women. And men's safe systems don't come back as robustly as women's to vaccinations against flu, yellow fever, measles, hepatitis and many other diseases. For the study, published online Dec 23, 2013 in the Proceedings of the National Academy of Sciences, the researchers analyzed the blood of nearly 90 adults after they received a seasonal flu shot.
Men with the highest testosterone levels had the worst effect to the flu vaccine across the board. Testosterone is tied to immortal man's sensual characteristics, such as muscle strength, beard growth and risk-taking. "We found a set of genes in men that when activated caused a jinxed response to the vaccine, but were not involved in female response. Some of these genes are regulated by testosterone".
It's testosterone's accomplish on these genes that causes the poor vaccine response. "This has a lot of implications for vaccine development". Vaccine comeback might be better if men were given twice the dose, he suggested, or peradventure if testosterone levels were reduced. The whole picture isn't in effect clear or simple. Men's weaker response to the flu vaccine is only seen for some strains of flu.
The flu vaccine is less impressive for men than women, and researchers at Stanford University suppose they've figured out why. The manly hormone testosterone causes genes in the immune arrangement to produce fewer antibodies, or defense mechanisms, in response to the vaccine, they found. "Men, typically, do worse than women in vaccinated response to infection and vaccination," said Stanford research affiliate David Furman, the lead study investigator.
For instance, men are more susceptible to bacterial, viral, fungal and parasitic infection than women. And men's safe systems don't come back as robustly as women's to vaccinations against flu, yellow fever, measles, hepatitis and many other diseases. For the study, published online Dec 23, 2013 in the Proceedings of the National Academy of Sciences, the researchers analyzed the blood of nearly 90 adults after they received a seasonal flu shot.
Men with the highest testosterone levels had the worst effect to the flu vaccine across the board. Testosterone is tied to immortal man's sensual characteristics, such as muscle strength, beard growth and risk-taking. "We found a set of genes in men that when activated caused a jinxed response to the vaccine, but were not involved in female response. Some of these genes are regulated by testosterone".
It's testosterone's accomplish on these genes that causes the poor vaccine response. "This has a lot of implications for vaccine development". Vaccine comeback might be better if men were given twice the dose, he suggested, or peradventure if testosterone levels were reduced. The whole picture isn't in effect clear or simple. Men's weaker response to the flu vaccine is only seen for some strains of flu.
Monday 20 January 2020
Using Non-Recommended Drugs For The Treatment Of Diabetes
Using Non-Recommended Drugs For The Treatment Of Diabetes.
Using the doubtful diabetes stupefy Avandia as an example, new research finds that doctors' prescribing patterns reshape across the country in response to warnings about medications from the US Food and Drug Administration. The denouement is that patients may be exposed to different levels of risk depending on where they live, the researchers said. "We were looking at the results black-box warnings for drugs have at a national level, and, more specifically, at a geographical level, and how these warnings are incorporated into practice," said office guide researcher Nilay D Shah, an assistant professor of health services research at the Mayo Clinic in Rochester, Minn.
In 2007, the FDA required that Avandia come with a "black-box warning" - the strongest foretoken admissible - alerting consumers that the drug was associated with an increased imperil of heart attack. Before the warning, Avandia was widely prescribed throughout the United States, although regional differences existed. "There was about a two-fold inequality in use before the warning - around 15,5 percent use in Oklahoma versus about 8 percent in North Dakota".
Right after the warning, the use of Avandia dropped dramatically, from a nationwide leading of 1,3 million monthly prescriptions in January 2007 to cruelly 317000 monthly prescriptions in June 2009. "There was a monumental decrease in use across the country. But there was absolutely a bit of residual use".
After the FDA warning, the researchers still found as much as a three-fold difference in use across the nation. In Oklahoma, Avandia use dropped to about 5,6 percent, but in North Dakota it tumbled to 1,9 percent. The reasons for the differences aren't clear. Some factors might take in how doctors are made apprised of FDA warnings and how they react.
Another piece could be the policy of state health guaranty plans, including Medicaid, in terms of covering drugs. Also, prominent doctors in given areas can pressurize the choice of drugs other doctors make. And drug-company marketing may play a role. "At this unit we don't have good insight into these differences".
Using the doubtful diabetes stupefy Avandia as an example, new research finds that doctors' prescribing patterns reshape across the country in response to warnings about medications from the US Food and Drug Administration. The denouement is that patients may be exposed to different levels of risk depending on where they live, the researchers said. "We were looking at the results black-box warnings for drugs have at a national level, and, more specifically, at a geographical level, and how these warnings are incorporated into practice," said office guide researcher Nilay D Shah, an assistant professor of health services research at the Mayo Clinic in Rochester, Minn.
In 2007, the FDA required that Avandia come with a "black-box warning" - the strongest foretoken admissible - alerting consumers that the drug was associated with an increased imperil of heart attack. Before the warning, Avandia was widely prescribed throughout the United States, although regional differences existed. "There was about a two-fold inequality in use before the warning - around 15,5 percent use in Oklahoma versus about 8 percent in North Dakota".
Right after the warning, the use of Avandia dropped dramatically, from a nationwide leading of 1,3 million monthly prescriptions in January 2007 to cruelly 317000 monthly prescriptions in June 2009. "There was a monumental decrease in use across the country. But there was absolutely a bit of residual use".
After the FDA warning, the researchers still found as much as a three-fold difference in use across the nation. In Oklahoma, Avandia use dropped to about 5,6 percent, but in North Dakota it tumbled to 1,9 percent. The reasons for the differences aren't clear. Some factors might take in how doctors are made apprised of FDA warnings and how they react.
Another piece could be the policy of state health guaranty plans, including Medicaid, in terms of covering drugs. Also, prominent doctors in given areas can pressurize the choice of drugs other doctors make. And drug-company marketing may play a role. "At this unit we don't have good insight into these differences".
Infection Of The Heart Valve Can Cause Death
Infection Of The Heart Valve Can Cause Death.
Life-threatening infections of the sentiment valve are twice as cheap in the United States as previously thought and have increased steadily in the hindmost 15 years, according to researchers. The new study also found that many cases of these infections - called endocarditis - are acquired in haleness care facilities and may be preventable. Without antibiotic treatment, these infections are fatal. Even with the best treatment, one in five patients with a resolution valve infection suffers a feeling attack or stroke and one in seven dies, according to study lead father Dr David Bor, chief of medicine and of infectious diseases at Cambridge Health Alliance in Massachusetts and an partner professor of medicine at Harvard Medical School.
He and a colleague analyzed public data and recorded 39000 hospitalizations for heart valve infections in 2009. Cases have increased 2,4 percent a year since 1998, they found. The findings were published online March 20 in the documentation PLoS One. Endocarditis is considered more uncommon, study co-author Dr John Brusch said in a Cambridge Health Alliance news programme release.
Life-threatening infections of the sentiment valve are twice as cheap in the United States as previously thought and have increased steadily in the hindmost 15 years, according to researchers. The new study also found that many cases of these infections - called endocarditis - are acquired in haleness care facilities and may be preventable. Without antibiotic treatment, these infections are fatal. Even with the best treatment, one in five patients with a resolution valve infection suffers a feeling attack or stroke and one in seven dies, according to study lead father Dr David Bor, chief of medicine and of infectious diseases at Cambridge Health Alliance in Massachusetts and an partner professor of medicine at Harvard Medical School.
He and a colleague analyzed public data and recorded 39000 hospitalizations for heart valve infections in 2009. Cases have increased 2,4 percent a year since 1998, they found. The findings were published online March 20 in the documentation PLoS One. Endocarditis is considered more uncommon, study co-author Dr John Brusch said in a Cambridge Health Alliance news programme release.
In The USA Every Fifth Child Has Special Needs
In The USA Every Fifth Child Has Special Needs.
The circuit tightening triggered by the current recession appears to have forced families to originate tough choices about care for children with chronic physical or emotion problems, a new swotting suggests in June 2013. The study, which was published in the June issue of the journal Health Affairs, reach-me-down a large government database to track out-of-pocket costs for families with privileged health insurance carriers from 2001 to 2009. Researchers were particularly interested in spending for children with certain health care needs.
And "Those are children who require health or related services beyond those required by children generally," said live researcher Pinar Karaca-Mandic, an assistant professor of supporters health at the University of Minnesota. "A child with asthma would fit in this category, for example. A toddler with depression, ADHD or a physical limitation would also fit this definition".
Nearly one in five children in the United States meets the criteria for having a valued health care need. Parents satisfy about twice as much to care for children with special needs as they do caring for children without ongoing problems. Their own well-being care costs usually go up, too, as they deal with the added emphasize of caregiving.
In the years leading up to the recession, out-of-pocket expenses climbed steadily for all family members - children and adults alike. But in 2007, the direction lines changed. For children who were mostly healthy, medical expenses jumped as insurance plans became less generous and families tire a greater share of the total tab for medical care.
Average annual out-of-pocket costs rose from about $280 in 2007 to $310 in 2009. But for children with prominent needs and adults, out-of-pocket costs in reality dropped. Adults cut spending on their own care by an normal of $40 if they had children without chronic conditions. In families with special-needs kids, adults pared their own medical bills by an customary of about $65 during each year of the recession.
Spending on children with special fitness care needs fell even further, by about $73 each year of the recession. Families spent an standard of $774 a year to care for children with special needs in 2007. By 2009, that drawing was down to $626. Taken together, researchers said it looks like parents cut back on their own heedfulness to continue to afford services for their kids.
The circuit tightening triggered by the current recession appears to have forced families to originate tough choices about care for children with chronic physical or emotion problems, a new swotting suggests in June 2013. The study, which was published in the June issue of the journal Health Affairs, reach-me-down a large government database to track out-of-pocket costs for families with privileged health insurance carriers from 2001 to 2009. Researchers were particularly interested in spending for children with certain health care needs.
And "Those are children who require health or related services beyond those required by children generally," said live researcher Pinar Karaca-Mandic, an assistant professor of supporters health at the University of Minnesota. "A child with asthma would fit in this category, for example. A toddler with depression, ADHD or a physical limitation would also fit this definition".
Nearly one in five children in the United States meets the criteria for having a valued health care need. Parents satisfy about twice as much to care for children with special needs as they do caring for children without ongoing problems. Their own well-being care costs usually go up, too, as they deal with the added emphasize of caregiving.
In the years leading up to the recession, out-of-pocket expenses climbed steadily for all family members - children and adults alike. But in 2007, the direction lines changed. For children who were mostly healthy, medical expenses jumped as insurance plans became less generous and families tire a greater share of the total tab for medical care.
Average annual out-of-pocket costs rose from about $280 in 2007 to $310 in 2009. But for children with prominent needs and adults, out-of-pocket costs in reality dropped. Adults cut spending on their own care by an normal of $40 if they had children without chronic conditions. In families with special-needs kids, adults pared their own medical bills by an customary of about $65 during each year of the recession.
Spending on children with special fitness care needs fell even further, by about $73 each year of the recession. Families spent an standard of $774 a year to care for children with special needs in 2007. By 2009, that drawing was down to $626. Taken together, researchers said it looks like parents cut back on their own heedfulness to continue to afford services for their kids.
Sunday 19 January 2020
Scientists Have Identified New Genes That Increase The Risk Of Alzheimer's Disease
Scientists Have Identified New Genes That Increase The Risk Of Alzheimer's Disease.
Scientists have pinpointed two genes that are linked to Alzheimer's c murrain and could become targets for supplementary treatments for the neurodegenerative condition. Genetic variants appear to treatment an important fragment in the development of Alzheimer's since having parents or siblings with the disease increases a person's risk. It is estimated that one of every five persons elderly 65 will develop Alzheimer's disease in their lifetime, the researchers added.
Genome-wide federation studies are increasing scientists' understanding of the biological pathways underlying Alzheimer's disease, which may hero to new therapies, said study author Dr Sudha Seshadri, an confederate professor of neurology at Boston University School of Medicine. For now, bourgeoisie should realize that genes likely interact with other genes and with environmental factors.
Maria Carrillo, senior pilot of medical and scientific relations at the Alzheimer's Association, said that "these are the types of studies we essential in terms of future genetic analysis and things must be confirmed in much larger samples, as was done in this study". The statement is published in the May 12 issue of the Journal of the American Medical Association.
Although it was known that three genes are culpable for rare cases of Alzheimer's disease that run in families, researchers had been steady of only one gene, apolipoprotein E (APOE), that increased the risk of the common type of Alzheimer's disease. Using a genome-wide relationship analysis study of 3006 people with Alzheimer's and 14642 commoners without the disease, Seshadri's group identified two other genes associated with Alzheimer's disease, located on chromosomes 2 and 19.
Scientists have pinpointed two genes that are linked to Alzheimer's c murrain and could become targets for supplementary treatments for the neurodegenerative condition. Genetic variants appear to treatment an important fragment in the development of Alzheimer's since having parents or siblings with the disease increases a person's risk. It is estimated that one of every five persons elderly 65 will develop Alzheimer's disease in their lifetime, the researchers added.
Genome-wide federation studies are increasing scientists' understanding of the biological pathways underlying Alzheimer's disease, which may hero to new therapies, said study author Dr Sudha Seshadri, an confederate professor of neurology at Boston University School of Medicine. For now, bourgeoisie should realize that genes likely interact with other genes and with environmental factors.
Maria Carrillo, senior pilot of medical and scientific relations at the Alzheimer's Association, said that "these are the types of studies we essential in terms of future genetic analysis and things must be confirmed in much larger samples, as was done in this study". The statement is published in the May 12 issue of the Journal of the American Medical Association.
Although it was known that three genes are culpable for rare cases of Alzheimer's disease that run in families, researchers had been steady of only one gene, apolipoprotein E (APOE), that increased the risk of the common type of Alzheimer's disease. Using a genome-wide relationship analysis study of 3006 people with Alzheimer's and 14642 commoners without the disease, Seshadri's group identified two other genes associated with Alzheimer's disease, located on chromosomes 2 and 19.
Saturday 18 January 2020
Docosahexaenoic Acid (DHA) Supplements For Breast-Feeding Mothers Is Good For Premature Infants
Docosahexaenoic Acid (DHA) Supplements For Breast-Feeding Mothers Is Good For Premature Infants.
Very too early infants have higher levels of DHA - an omega-3 fatty acid that's basic to the improvement and development of the brain - when their breast-feeding mothers believe DHA supplements, Canadian researchers have found. Researchers say a deficiency in DHA (docosahexaenoic acid) is common in very preterm infants, possibly because the ordinary diets of many in the or breast-feeding women lack the essential fatty acid, which is found in cold water fatty fish and fish lubricator supplements.
The study included breast-feeding mothers of 12 infants born at 29 weeks gestation or earlier. The mothers were given high-priced doses of DHA supplements until 36 weeks after conception. The mothers and babies in this intervention series were compared at date 49 to a control group of mothers of very preterm infants who didn't take DHA supplements.
The levels of DHA in the knocker milk of mothers who took DHA supplements were nearly 12 times higher than in the draw off of mothers in the control group. Infants in the intervention group received about seven times more DHA than those in the hold back group. Plasma DHA concentrations in mothers and babies in the intervention league were two to three times higher than those in the control group.
So "Our study has shown that supplementing mothers is a usable and effective way of providing DHA to low birthweight premature infants," review author Dr Isabelle Marc, an assistant professor in the pediatrics department at Laval University in Quebec, said in a item release. The DHA content in the breast drain of mothers who don't consume fish during the breast-feeding period is probably insufficient, according to Marc.
Very too early infants have higher levels of DHA - an omega-3 fatty acid that's basic to the improvement and development of the brain - when their breast-feeding mothers believe DHA supplements, Canadian researchers have found. Researchers say a deficiency in DHA (docosahexaenoic acid) is common in very preterm infants, possibly because the ordinary diets of many in the or breast-feeding women lack the essential fatty acid, which is found in cold water fatty fish and fish lubricator supplements.
The study included breast-feeding mothers of 12 infants born at 29 weeks gestation or earlier. The mothers were given high-priced doses of DHA supplements until 36 weeks after conception. The mothers and babies in this intervention series were compared at date 49 to a control group of mothers of very preterm infants who didn't take DHA supplements.
The levels of DHA in the knocker milk of mothers who took DHA supplements were nearly 12 times higher than in the draw off of mothers in the control group. Infants in the intervention group received about seven times more DHA than those in the hold back group. Plasma DHA concentrations in mothers and babies in the intervention league were two to three times higher than those in the control group.
So "Our study has shown that supplementing mothers is a usable and effective way of providing DHA to low birthweight premature infants," review author Dr Isabelle Marc, an assistant professor in the pediatrics department at Laval University in Quebec, said in a item release. The DHA content in the breast drain of mothers who don't consume fish during the breast-feeding period is probably insufficient, according to Marc.
Use Of Finasteride Reduces Alcohol Consumption
Use Of Finasteride Reduces Alcohol Consumption.
Some men who use finasteride (Propecia) to balm Donnybrook baldness may also be drinking less alcohol, a new study suggests June 2013. Among the potency side effects of the hair-restoring drug are a reduced sex drive, concavity and suicidal thoughts. And it's men who have sexual side effects who also appear to want to guzzle less, the researchers report. "In men experiencing persistent sexual side junk despite stopping finasteride, two-thirds have noticed drinking less alcohol than before taking finasteride," said analysis author Dr Michael Irwig, an assistant professor of medicine at George Washington University School of Medicine and Health Sciences in Washington, DC.
Although it isn't obvious why the medication might have this effect, Irwig thinks the dull may alter the brain's chemistry. "Finasteride interferes with the brain's capability to make certain hormones called neurosteroids, which are likely linked to drinking alcohol. For younger men contemplating the use of finasteride for manly pattern hair loss, they should carefully up the modest cosmetic benefits of less hair loss versus some of the serious risks".
The report was published online June 13 in the almanac Alcoholism: Clinical and Experimental Research. "The biggest object to with this finding is that it is naturalistic rather than a controlled study so cause-and-effect is hard to establish," said James Garbutt, a professor of psychiatry at the University of North Carolina at Chapel Hill. "This is more of a cloud on the vista than a clear-cut effect".
If these findings are confirmed it suggests there may be a subgroup of people, it is possible that identifiable by their exposure of sexual side effects, who will experience reductions in alcohol consumption who was not involved with the study. "Based on the consumption levels reported in the paper, this denizens would be considered social drinkers and not delinquent drinkers".
Some men who use finasteride (Propecia) to balm Donnybrook baldness may also be drinking less alcohol, a new study suggests June 2013. Among the potency side effects of the hair-restoring drug are a reduced sex drive, concavity and suicidal thoughts. And it's men who have sexual side effects who also appear to want to guzzle less, the researchers report. "In men experiencing persistent sexual side junk despite stopping finasteride, two-thirds have noticed drinking less alcohol than before taking finasteride," said analysis author Dr Michael Irwig, an assistant professor of medicine at George Washington University School of Medicine and Health Sciences in Washington, DC.
Although it isn't obvious why the medication might have this effect, Irwig thinks the dull may alter the brain's chemistry. "Finasteride interferes with the brain's capability to make certain hormones called neurosteroids, which are likely linked to drinking alcohol. For younger men contemplating the use of finasteride for manly pattern hair loss, they should carefully up the modest cosmetic benefits of less hair loss versus some of the serious risks".
The report was published online June 13 in the almanac Alcoholism: Clinical and Experimental Research. "The biggest object to with this finding is that it is naturalistic rather than a controlled study so cause-and-effect is hard to establish," said James Garbutt, a professor of psychiatry at the University of North Carolina at Chapel Hill. "This is more of a cloud on the vista than a clear-cut effect".
If these findings are confirmed it suggests there may be a subgroup of people, it is possible that identifiable by their exposure of sexual side effects, who will experience reductions in alcohol consumption who was not involved with the study. "Based on the consumption levels reported in the paper, this denizens would be considered social drinkers and not delinquent drinkers".
New Research Of Children's Autism
New Research Of Children's Autism.
An speculative drug for autism did not pick up levels of lethargy and social withdrawal in children who took it, but it did show some other benefits, a budding study finds in May 2013. Children on arbaclofen did improve on an overall measure of autism starkness when compared to kids taking an inactive placebo, said lead researcher Dr Jeremy Veenstra-VanderWeele, an associate professor of psychiatry, pediatrics and pharmacology at Vanderbilt University. He is to present the findings Thursday at the International Meeting for Autism Research (IMFAR) in Spain.
One of 88 children in the United States is now diagnosed with an autism spectrum disorder, the parasol call for complex brain phenomenon disorders marked by problems in social interaction and communication. Veenstra-VanderWeele focused on evaluating the public improvement with the drug because earlier research had suggested it could help. However, one of the earlier studies did not analogize the drug to a placebo, but simply measured improvement in those who took the drug.
In the new study, Veenstra-VanderWeele and his line-up assigned 150 people with autism, aged 5 to 21, to take the cure-all or a placebo, without knowing which group they were in, for eight weeks. The participants had been diagnosed with autistic disorder, Asperger's syndrome or another interconnected condition known as pervasive developmental disorder. In all, 130 finished the study.
An speculative drug for autism did not pick up levels of lethargy and social withdrawal in children who took it, but it did show some other benefits, a budding study finds in May 2013. Children on arbaclofen did improve on an overall measure of autism starkness when compared to kids taking an inactive placebo, said lead researcher Dr Jeremy Veenstra-VanderWeele, an associate professor of psychiatry, pediatrics and pharmacology at Vanderbilt University. He is to present the findings Thursday at the International Meeting for Autism Research (IMFAR) in Spain.
One of 88 children in the United States is now diagnosed with an autism spectrum disorder, the parasol call for complex brain phenomenon disorders marked by problems in social interaction and communication. Veenstra-VanderWeele focused on evaluating the public improvement with the drug because earlier research had suggested it could help. However, one of the earlier studies did not analogize the drug to a placebo, but simply measured improvement in those who took the drug.
In the new study, Veenstra-VanderWeele and his line-up assigned 150 people with autism, aged 5 to 21, to take the cure-all or a placebo, without knowing which group they were in, for eight weeks. The participants had been diagnosed with autistic disorder, Asperger's syndrome or another interconnected condition known as pervasive developmental disorder. In all, 130 finished the study.
Some Types Of Antidepressants Increase The Risk Of Miscarriage
Some Types Of Antidepressants Increase The Risk Of Miscarriage.
Women who engage a steady class of antidepressants during pregnancy may increase their risk of having a frustration by 68 percent, Canadian researchers report. Antidepressant use is common during pregnancy, with up to 3,7 percent of women taking the drugs during the essential trimester. Stopping treatment can lead to a return of depression and other symptoms, and earlier studies of the medications' effects on the fetus have been small and had contradictory results.
But the Canadian case-control mull over on more than 5000 women found that by controlling for other factors associated with miscarriage, taking antidepressants known as eclectic serotonin reuptake inhibitors (SSRIs) during pregnancy led to an increased risk of miscarriage. Up to 20 percent - or one baggage out of five - will suffer a miscarriage for various reasons during pregnancy. But the inspect results suggest that SSRIs as a class increase that risk, according to lead researcher Anick Berard, an confederate professor at the University of Montreal.
The results "are highly robust given the big-hearted number of users studied". In addition the study makes clear that the drugs, rather than the mothers' despondency and anxiety, are associated with an increased risk for miscarriage.
However, the author of an accompanying editorial famed that the finding is far from definitive. "This is an association, not a cause," said Adrienne Einarson, assistant headman of the Motherisk Program at the Hospital for Sick Children in Toronto. "We still don't know if it's the impression or the drug".
Also, the risk uncovered by the study is a very small one. "Less than twice as many women had miscarriages in the classify with antidepressants as those who did not take antidepressants. It's a very small risk indeed, and it's not a common sense to stop taking an antidepressant if you need it".
Women who engage a steady class of antidepressants during pregnancy may increase their risk of having a frustration by 68 percent, Canadian researchers report. Antidepressant use is common during pregnancy, with up to 3,7 percent of women taking the drugs during the essential trimester. Stopping treatment can lead to a return of depression and other symptoms, and earlier studies of the medications' effects on the fetus have been small and had contradictory results.
But the Canadian case-control mull over on more than 5000 women found that by controlling for other factors associated with miscarriage, taking antidepressants known as eclectic serotonin reuptake inhibitors (SSRIs) during pregnancy led to an increased risk of miscarriage. Up to 20 percent - or one baggage out of five - will suffer a miscarriage for various reasons during pregnancy. But the inspect results suggest that SSRIs as a class increase that risk, according to lead researcher Anick Berard, an confederate professor at the University of Montreal.
The results "are highly robust given the big-hearted number of users studied". In addition the study makes clear that the drugs, rather than the mothers' despondency and anxiety, are associated with an increased risk for miscarriage.
However, the author of an accompanying editorial famed that the finding is far from definitive. "This is an association, not a cause," said Adrienne Einarson, assistant headman of the Motherisk Program at the Hospital for Sick Children in Toronto. "We still don't know if it's the impression or the drug".
Also, the risk uncovered by the study is a very small one. "Less than twice as many women had miscarriages in the classify with antidepressants as those who did not take antidepressants. It's a very small risk indeed, and it's not a common sense to stop taking an antidepressant if you need it".
Friday 17 January 2020
Doctors Recommend That Pregnant Women Have To Make A Flu Shot
Doctors Recommend That Pregnant Women Have To Make A Flu Shot.
Pregnant women were urged to get a flu launch during the 2009 H1N1 pandemic, and further display supports that advice. Norwegian researchers have found that vaccination in pregnancy was safe for origin and child, and that fetal deaths were more common among unvaccinated moms-to-be. Influenza is a serious intimation to a pregnant woman and her unborn child, said Dr Camilla Stoltenberg, director vague of the Norwegian Institute of Public Health in Oslo, lead researcher of the new study. "Our look at indicates that influenza during pregnancy was a risk factor for stillbirth during the pandemic in 2009".
And "We judge no indication that pandemic vaccination in the second or third trimester increased the risk of stillbirth". With this year's flu pummeling many folk across the United States, experts reveal the best way a pregnant woman can protect her unborn baby from flu complications is by getting a flu shot. "In adding to protecting the mother against severe influenza, the vaccine protects the fetus and the lassie in the first months after birth, when the child is too young to be vaccinated".
The US Centers for Disease Control and Prevention recommends a flu spot for everyone over 6 months of age. Besides replete women, the CDC says the elderly and anyone with a chronic condition such as asthma or diabetes are especially vulnerable to infection.
For the study, published Jan 16, 2013 in the New England Journal of Medicine, Stoltenberg's crew cool data on more than 117000 women in Norway who were pregnant between 2009 and 2010 - the take of the H1N1 pandemic. The investigators found the rate of fetal deaths was almost five per 1000 women.
Pregnant women were urged to get a flu launch during the 2009 H1N1 pandemic, and further display supports that advice. Norwegian researchers have found that vaccination in pregnancy was safe for origin and child, and that fetal deaths were more common among unvaccinated moms-to-be. Influenza is a serious intimation to a pregnant woman and her unborn child, said Dr Camilla Stoltenberg, director vague of the Norwegian Institute of Public Health in Oslo, lead researcher of the new study. "Our look at indicates that influenza during pregnancy was a risk factor for stillbirth during the pandemic in 2009".
And "We judge no indication that pandemic vaccination in the second or third trimester increased the risk of stillbirth". With this year's flu pummeling many folk across the United States, experts reveal the best way a pregnant woman can protect her unborn baby from flu complications is by getting a flu shot. "In adding to protecting the mother against severe influenza, the vaccine protects the fetus and the lassie in the first months after birth, when the child is too young to be vaccinated".
The US Centers for Disease Control and Prevention recommends a flu spot for everyone over 6 months of age. Besides replete women, the CDC says the elderly and anyone with a chronic condition such as asthma or diabetes are especially vulnerable to infection.
For the study, published Jan 16, 2013 in the New England Journal of Medicine, Stoltenberg's crew cool data on more than 117000 women in Norway who were pregnant between 2009 and 2010 - the take of the H1N1 pandemic. The investigators found the rate of fetal deaths was almost five per 1000 women.
Experts Urge Parents To Buy Kids Sunglasses Against Ultraviolet Radiation
Experts Urge Parents To Buy Kids Sunglasses Against Ultraviolet Radiation.
With May designated as UV awareness month, experts are occupation on parents to give particular heed to the safety of their children's eyes this summer. Although eye keeping is a concern for people of all ages, Prevent Blindness America, the nation's oldest eye healthiness and safety organization, warns that children are particularly vulnerable to the harmful ultraviolet A and B (UVA and UVB) price that can accompany sun exposure. For one, children in the main spend more time in the sun, the group noted.
In addition, the organization highlights the American Optometric Association's cautionary judgement that the lenses of young eyes are more transparent than that of adults, risking retinal location to a greater degree of short wavelength light. "We need to remember to take care of our eyes from UV every day of the year," Hugh R Parry, president and CEO of Prevent Blindness America, said in a communication release. "UV rays reflecting off the water, sand, pavement and even snow are uncommonly dangerous. We can encourage our children to wear the proper ogle protection by leading by example".
UV exposure has been linked to the onset of cataracts, macular degeneration and a major array of eye health issues, the experts noted. Prevent Blindness America advises that each and every one who goes out in the sun should wear sunglasses that block out 99 percent to 100 percent of both UVA and UVB dispersal - noting that sunglasses without such protection can actually cause the pupils to dilate, thereby doing more hurt than good. A wide-brimmed hat or cap also offers some measure of eye protection, the batch suggested.
With specific respect to children, Prevent Blindness America further encourages parents to make safe that sunglasses fit their child's face properly and shields the sun's rays from all directions. The league points out that wrap-around sunglasses might be optimal in the later regard, because they additionally defend the skin immediately surrounding a child's eyes. Sunglasses, they note, should always be composed of impact-resistant polycarbonates, rather than glass, and should be scratch-free.
With May designated as UV awareness month, experts are occupation on parents to give particular heed to the safety of their children's eyes this summer. Although eye keeping is a concern for people of all ages, Prevent Blindness America, the nation's oldest eye healthiness and safety organization, warns that children are particularly vulnerable to the harmful ultraviolet A and B (UVA and UVB) price that can accompany sun exposure. For one, children in the main spend more time in the sun, the group noted.
In addition, the organization highlights the American Optometric Association's cautionary judgement that the lenses of young eyes are more transparent than that of adults, risking retinal location to a greater degree of short wavelength light. "We need to remember to take care of our eyes from UV every day of the year," Hugh R Parry, president and CEO of Prevent Blindness America, said in a communication release. "UV rays reflecting off the water, sand, pavement and even snow are uncommonly dangerous. We can encourage our children to wear the proper ogle protection by leading by example".
UV exposure has been linked to the onset of cataracts, macular degeneration and a major array of eye health issues, the experts noted. Prevent Blindness America advises that each and every one who goes out in the sun should wear sunglasses that block out 99 percent to 100 percent of both UVA and UVB dispersal - noting that sunglasses without such protection can actually cause the pupils to dilate, thereby doing more hurt than good. A wide-brimmed hat or cap also offers some measure of eye protection, the batch suggested.
With specific respect to children, Prevent Blindness America further encourages parents to make safe that sunglasses fit their child's face properly and shields the sun's rays from all directions. The league points out that wrap-around sunglasses might be optimal in the later regard, because they additionally defend the skin immediately surrounding a child's eyes. Sunglasses, they note, should always be composed of impact-resistant polycarbonates, rather than glass, and should be scratch-free.
Another Genetic Cause Of Alzheimer's Disease
Another Genetic Cause Of Alzheimer's Disease.
Researchers have discovered that the variation of a gene associated with beginning onset Alzheimer's may block a key recycling process demanded for brain cell survival - a finding that points the way to possible treatment for the disease. When it's working properly, this gene - called presenilin 1 (PS1) - performs a vital house-cleaning utility by helping brain cells digest unwanted, damaged and potentially toxic proteins.
But in its mutated form, the gene fails to supporter cells recycle these capability toxins, suggesting an explanation for the damage to the brain characteristic of Alzheimer's disease. "We hold we have identified the principal mechanism by which mutations of PS1 cause the most common genetic appear of Alzheimer's disease," study co-author Dr Ralph A Nixon, professor in the departments of psychiatry and chamber biology as well as director of NYU's Center of Excellence on Brain Aging and the Silberstein Alzheimer's Institute, said in a university rumour release.
And "Presently, no effective treatment exists to either unproductive or prevent the progression of Alzheimer's disease," added Nixon, also director of the Center for Dementia Research at the Nathan S Kline Institute for Psychiatric Research in New York City. "This unearthing has the the of identifying such a treatment".
Researchers have discovered that the variation of a gene associated with beginning onset Alzheimer's may block a key recycling process demanded for brain cell survival - a finding that points the way to possible treatment for the disease. When it's working properly, this gene - called presenilin 1 (PS1) - performs a vital house-cleaning utility by helping brain cells digest unwanted, damaged and potentially toxic proteins.
But in its mutated form, the gene fails to supporter cells recycle these capability toxins, suggesting an explanation for the damage to the brain characteristic of Alzheimer's disease. "We hold we have identified the principal mechanism by which mutations of PS1 cause the most common genetic appear of Alzheimer's disease," study co-author Dr Ralph A Nixon, professor in the departments of psychiatry and chamber biology as well as director of NYU's Center of Excellence on Brain Aging and the Silberstein Alzheimer's Institute, said in a university rumour release.
And "Presently, no effective treatment exists to either unproductive or prevent the progression of Alzheimer's disease," added Nixon, also director of the Center for Dementia Research at the Nathan S Kline Institute for Psychiatric Research in New York City. "This unearthing has the the of identifying such a treatment".
Surgery For Fibromyalgia Treatment
Surgery For Fibromyalgia Treatment.
An implanted cognizance that zaps the nerves at the nape of the neck - shown in operation in treating some people with migraines - may also help informality the ache of fibromyalgia, an ailment that causes widespread body pain and tenderness. A Belgian scientist treated reduced numbers of fibromyalgia patients with "occipital nerve stimulation," which rouses the occipital nerves just below the skin at the back of the neck using an implanted device. Dr Mark Plazier found that misery scores dropped for 20 of 25 patients using this device over six months and their quality of sustenance improved significantly.
And "There are only a few treatment options for fibromyalgia right now and the response to treatment is far from 100 percent, which implies there are a lot of patients still looking for daily to get a better life. This treatment might be an excellent privilege for them," said Plazier, a neurosurgeon at University Hospital Antwerp. But, "it is thorny to determine the impact of these findings on fibromyalgia patients, since larger trials are necessary".
Plazier is to present his digging this week at a meeting of the International Neuromodulation Society, in Berlin. Neuromodulation is a group of therapies that use medical devices to aid symptoms or restore abilities by altering nerve system function.
Research presented at systematic conferences has not typically been peer-reviewed or published and is considered preliminary.
An implanted cognizance that zaps the nerves at the nape of the neck - shown in operation in treating some people with migraines - may also help informality the ache of fibromyalgia, an ailment that causes widespread body pain and tenderness. A Belgian scientist treated reduced numbers of fibromyalgia patients with "occipital nerve stimulation," which rouses the occipital nerves just below the skin at the back of the neck using an implanted device. Dr Mark Plazier found that misery scores dropped for 20 of 25 patients using this device over six months and their quality of sustenance improved significantly.
And "There are only a few treatment options for fibromyalgia right now and the response to treatment is far from 100 percent, which implies there are a lot of patients still looking for daily to get a better life. This treatment might be an excellent privilege for them," said Plazier, a neurosurgeon at University Hospital Antwerp. But, "it is thorny to determine the impact of these findings on fibromyalgia patients, since larger trials are necessary".
Plazier is to present his digging this week at a meeting of the International Neuromodulation Society, in Berlin. Neuromodulation is a group of therapies that use medical devices to aid symptoms or restore abilities by altering nerve system function.
Research presented at systematic conferences has not typically been peer-reviewed or published and is considered preliminary.
Vitamin E Fights Against Diseases
Vitamin E Fights Against Diseases.
There might be some credible news in the wrangle against Alzheimer's disease: A new study suggests that a large daily dose of vitamin E might labourer slow progression of the memory-robbing illness. Alzheimer's patients given a "pharmacological" portion of vitamin E experienced slower declines in thinking and memory and required less caregiver metre than those taking a placebo, said Dr Maurice Dysken, lead author of a new study published Dec 31, 2013 in the Journal of the American Medical Association. "We found vitamin E significantly slowed the have a claim to of advance versus placebo," said Dysken, who is with the Geriatric Research Education and Clinical Center of the Minneapolis VA Health Care System.
Experts stressed, however, that vitamin E does not seem to wrestle the underlying cause of Alzheimer's and is in no nature a cure. The study involved more than 600 patients at 14 VA medical centers with kind to moderate Alzheimer's. Researchers separation the group into quarters, with each receiving a different therapy. One-quarter received a daily dose of 2000 supranational units (IU) of alpha tocopherol, a form of vitamin E That's a to some degree large dose; by comparison, a daily multivitamin contains only about 100 IUs of vitamin E.
The other sets of patients were given the Alzheimer's medication memantine, a syndication of vitamin E and memantine, or a placebo. People who took vitamin E merely experienced a 19 percent reduction in their annual estimate of decline compared to a placebo during the study's average 2,3 years of follow-up, the researchers said. In reasonable terms, this means the vitamin E group enjoyed a more than six-month hold up in the progression of Alzheimer's, the researchers said.
This delay could mean a lot to patients, the researchers said, noting that the settle experienced by the placebo group could translate into the complete loss of the ability to dress or bathe independently. The researchers also found that ancestors in the vitamin E group needed about two fewer hours of tribulation each day. Neither memantine nor the combination of vitamin E plus memantine showed clinical benefits in this trial. Therapy with vitamin E also appears to be safe, with no increased jeopardize of malady or death, the researchers found.
There might be some credible news in the wrangle against Alzheimer's disease: A new study suggests that a large daily dose of vitamin E might labourer slow progression of the memory-robbing illness. Alzheimer's patients given a "pharmacological" portion of vitamin E experienced slower declines in thinking and memory and required less caregiver metre than those taking a placebo, said Dr Maurice Dysken, lead author of a new study published Dec 31, 2013 in the Journal of the American Medical Association. "We found vitamin E significantly slowed the have a claim to of advance versus placebo," said Dysken, who is with the Geriatric Research Education and Clinical Center of the Minneapolis VA Health Care System.
Experts stressed, however, that vitamin E does not seem to wrestle the underlying cause of Alzheimer's and is in no nature a cure. The study involved more than 600 patients at 14 VA medical centers with kind to moderate Alzheimer's. Researchers separation the group into quarters, with each receiving a different therapy. One-quarter received a daily dose of 2000 supranational units (IU) of alpha tocopherol, a form of vitamin E That's a to some degree large dose; by comparison, a daily multivitamin contains only about 100 IUs of vitamin E.
The other sets of patients were given the Alzheimer's medication memantine, a syndication of vitamin E and memantine, or a placebo. People who took vitamin E merely experienced a 19 percent reduction in their annual estimate of decline compared to a placebo during the study's average 2,3 years of follow-up, the researchers said. In reasonable terms, this means the vitamin E group enjoyed a more than six-month hold up in the progression of Alzheimer's, the researchers said.
This delay could mean a lot to patients, the researchers said, noting that the settle experienced by the placebo group could translate into the complete loss of the ability to dress or bathe independently. The researchers also found that ancestors in the vitamin E group needed about two fewer hours of tribulation each day. Neither memantine nor the combination of vitamin E plus memantine showed clinical benefits in this trial. Therapy with vitamin E also appears to be safe, with no increased jeopardize of malady or death, the researchers found.
Parkinson's Disease Affects Humanity
Parkinson's Disease Affects Humanity.
A long-term use program may help calm depression in people with Parkinson's disease, according to a new, small study Dec 2013. Researchers looked at 31 Parkinson's patients who were randomly assigned to an "early start" heap that did an put to use program for 48 weeks or a "late start" group that worked out for 24 weeks. The program included three one-hour cardiovascular and denial training workouts a week.
Depression symptoms improved much more amid the patients in the 48-week group than among those in the 24-week group. This is vital because mood is often more debilitating than movement problems for Parkinson's patients, said study leader Dr Ariane Park, a action disorder neurologist at Ohio State University's Wexner Medical Center. The examination was published online recently in the journal Parkinsonism andamp; Related Disorders.
A long-term use program may help calm depression in people with Parkinson's disease, according to a new, small study Dec 2013. Researchers looked at 31 Parkinson's patients who were randomly assigned to an "early start" heap that did an put to use program for 48 weeks or a "late start" group that worked out for 24 weeks. The program included three one-hour cardiovascular and denial training workouts a week.
Depression symptoms improved much more amid the patients in the 48-week group than among those in the 24-week group. This is vital because mood is often more debilitating than movement problems for Parkinson's patients, said study leader Dr Ariane Park, a action disorder neurologist at Ohio State University's Wexner Medical Center. The examination was published online recently in the journal Parkinsonism andamp; Related Disorders.
Thursday 16 January 2020
Contrave, A New Weight Loss Pill Combines Anti-Addiction Medication And An Antidepressant
Contrave, A New Weight Loss Pill Combines Anti-Addiction Medication And An Antidepressant.
An dexterous monitory panel recommended on Tuesday that Contrave, a unknown weight-loss pill that combines an antidepressant with an anti-addiction medication, be approved by the US Food and Drug Administration. The 13-7 preference in favor of Contrave came amid agency concerns that the numb might raise blood pressure in some patients and increase the risk of heart attacks and strokes centre of some users, according to the Associated Press. But panelists voted 11-8 earlier in the heyday that those potential health risks could be studied after Contrave was approved.
The FDA does not have to follow the advice of its advisory committees, but it typically does. The mechanism is expected to make a decision on Contrave by Jan 31, 2011, the wire utilization reported. Contrave is manufactured by Orexigen Therapeutics Inc. In October, the FDA voted against approving two other weight-loss drugs, Arena Pharmaceuticals' lorcaserin and Vivus' Qnexa, because of cover concerns, according to the AP. Last July, a muse about funded by Orexigen and published in The Lancet found that Contrave helped users pour pounds when taken along with a well diet and exercise.
People who took the drug for more than a year lost an average of 5 percent or more of body weight, depending on the dosage used, the team said. However, the regimen did come with side effects, and about half of scan participants dropped out before completing a year of treatment. Contrave is combination of two familiar drugs, naltrexone (Revia, used to fight addictions) and the antidepressant bupropion (known by a host of names, including Wellbutrin).
The drug appears to boost weight loss by changing the workings of the body's essential nervous system, the researchers said. The study enrolled men (15 percent) and women (85 percent) from around the country, ranging in epoch from 18 to 65. They were all either pudgy or overweightm, with high blood fat levels or high blood pressure.
An dexterous monitory panel recommended on Tuesday that Contrave, a unknown weight-loss pill that combines an antidepressant with an anti-addiction medication, be approved by the US Food and Drug Administration. The 13-7 preference in favor of Contrave came amid agency concerns that the numb might raise blood pressure in some patients and increase the risk of heart attacks and strokes centre of some users, according to the Associated Press. But panelists voted 11-8 earlier in the heyday that those potential health risks could be studied after Contrave was approved.
The FDA does not have to follow the advice of its advisory committees, but it typically does. The mechanism is expected to make a decision on Contrave by Jan 31, 2011, the wire utilization reported. Contrave is manufactured by Orexigen Therapeutics Inc. In October, the FDA voted against approving two other weight-loss drugs, Arena Pharmaceuticals' lorcaserin and Vivus' Qnexa, because of cover concerns, according to the AP. Last July, a muse about funded by Orexigen and published in The Lancet found that Contrave helped users pour pounds when taken along with a well diet and exercise.
People who took the drug for more than a year lost an average of 5 percent or more of body weight, depending on the dosage used, the team said. However, the regimen did come with side effects, and about half of scan participants dropped out before completing a year of treatment. Contrave is combination of two familiar drugs, naltrexone (Revia, used to fight addictions) and the antidepressant bupropion (known by a host of names, including Wellbutrin).
The drug appears to boost weight loss by changing the workings of the body's essential nervous system, the researchers said. The study enrolled men (15 percent) and women (85 percent) from around the country, ranging in epoch from 18 to 65. They were all either pudgy or overweightm, with high blood fat levels or high blood pressure.
Treatment Of Heart Attack With The Help Of Stem Cells From Belly Fat
Treatment Of Heart Attack With The Help Of Stem Cells From Belly Fat.
Stem cells enchanted from the belly unctuous of 10 love attack patients managed to improve several measures of heart function, Dutch researchers report. This is the premier time this type of therapy has been used in humans, said the scientists, who presented their findings Tuesday at the American Heart Association's annual gathering in Chicago. But the improvements, though to some degree dramatic in this small group of patients, were not statistically significant, probably due to the minimal number of participants in the study.
And another expert urged caution when interpreting the results. "The opener issue is whether a treatment makes us live longer or feel better," said Dr Jeffrey S Borer, rocking-chair of the department of medicine and of cardiovascular medicine at the State University of New York (SUNY) Downstate Medical Center in New York City. This workroom only looked at "surrogates," import measures of heart function that might predict better future health in the patient.
So "This cannot be interpreted as if they instantly represent positive clinical outcomes. These certainly are reassuring stem cell data, but there's a great deal more to do before it is possible to know whether this is a viable therapy".
Another caveat: All the patients in this experimental were white Europeans. The study authors believe the results could be extrapolated to much of the US population, but not unavoidably to people who aren't white. Fat tissue yields many more stem-post cells than bone marrow (which has been studied before) and is much easier to access.
In bone marrow, 40 cubic centimeters (cc) typically revenue about 25000 stem cells, which is "not nearly enough to treat men and women with," said study author Dr Eric Duckers, head of the Molecular Cardiology Laboratory at Thoraxcenter, Erasmus University Medical Center in Rotterdam. To get enough cells to exert oneself with, those arrest cells would have to be cultured, a process that can take six to eight weeks.
Stem cells enchanted from the belly unctuous of 10 love attack patients managed to improve several measures of heart function, Dutch researchers report. This is the premier time this type of therapy has been used in humans, said the scientists, who presented their findings Tuesday at the American Heart Association's annual gathering in Chicago. But the improvements, though to some degree dramatic in this small group of patients, were not statistically significant, probably due to the minimal number of participants in the study.
And another expert urged caution when interpreting the results. "The opener issue is whether a treatment makes us live longer or feel better," said Dr Jeffrey S Borer, rocking-chair of the department of medicine and of cardiovascular medicine at the State University of New York (SUNY) Downstate Medical Center in New York City. This workroom only looked at "surrogates," import measures of heart function that might predict better future health in the patient.
So "This cannot be interpreted as if they instantly represent positive clinical outcomes. These certainly are reassuring stem cell data, but there's a great deal more to do before it is possible to know whether this is a viable therapy".
Another caveat: All the patients in this experimental were white Europeans. The study authors believe the results could be extrapolated to much of the US population, but not unavoidably to people who aren't white. Fat tissue yields many more stem-post cells than bone marrow (which has been studied before) and is much easier to access.
In bone marrow, 40 cubic centimeters (cc) typically revenue about 25000 stem cells, which is "not nearly enough to treat men and women with," said study author Dr Eric Duckers, head of the Molecular Cardiology Laboratory at Thoraxcenter, Erasmus University Medical Center in Rotterdam. To get enough cells to exert oneself with, those arrest cells would have to be cultured, a process that can take six to eight weeks.
Repeated Brain Concussion Can Lead To Disability
Repeated Brain Concussion Can Lead To Disability.
After taking a distressingly hit to the perceptiveness during a football game, an Indiana high school student suffered severe headaches for the next three days. Following a crescendo CT scan that was normal, his doctor told him to respite to go back on the field until he felt better. But the boy returned to practice, where he suffered a devastating brains injury called second impact syndrome. More than six years later, Cody Lehe, now 23, is mostly wheelchair-bound and struggles with diminished mad capacity.
Yet he's fortunate to be alive: Second modify syndrome is fatal in about 85 percent of cases. "It's a unique syndrome of sense injury that appears in high school and younger athletes when they have a mild concussion, and then have a bat head impact before they're over the symptoms of their first impact. This leads to massive knowledge swelling almost immediately," said Dr Michael Turner, a neurosurgeon at Goodman Campbell Brain and Spine at the Indiana University School of Medicine, and co-author of a rejuvenated report on Cody's case, published Jan. 1 in the Journal of Neurosurgery: Pediatrics.
The casing study illustrates why it's so notable to prevent a second impact and give a young brain the chance to rest and recover, another wizard said. "Second impact syndrome is a very rare phenomenon. It's estimated to occur about five times a year in the country," said Kenneth Podell, a neuropsychologist and co-director of the Methodist Concussion Center in Houston.
So "What makes this deliberate over unique: They're the initially ones to in actuality have a CT scan after the first hit. What they were able to show is that the first CT scan was read as normal," said Podell, who also is a rig consultant for the Houston Texans, of the NFL. "After the first concussion there was no clue of any significant injury.
After taking a distressingly hit to the perceptiveness during a football game, an Indiana high school student suffered severe headaches for the next three days. Following a crescendo CT scan that was normal, his doctor told him to respite to go back on the field until he felt better. But the boy returned to practice, where he suffered a devastating brains injury called second impact syndrome. More than six years later, Cody Lehe, now 23, is mostly wheelchair-bound and struggles with diminished mad capacity.
Yet he's fortunate to be alive: Second modify syndrome is fatal in about 85 percent of cases. "It's a unique syndrome of sense injury that appears in high school and younger athletes when they have a mild concussion, and then have a bat head impact before they're over the symptoms of their first impact. This leads to massive knowledge swelling almost immediately," said Dr Michael Turner, a neurosurgeon at Goodman Campbell Brain and Spine at the Indiana University School of Medicine, and co-author of a rejuvenated report on Cody's case, published Jan. 1 in the Journal of Neurosurgery: Pediatrics.
The casing study illustrates why it's so notable to prevent a second impact and give a young brain the chance to rest and recover, another wizard said. "Second impact syndrome is a very rare phenomenon. It's estimated to occur about five times a year in the country," said Kenneth Podell, a neuropsychologist and co-director of the Methodist Concussion Center in Houston.
So "What makes this deliberate over unique: They're the initially ones to in actuality have a CT scan after the first hit. What they were able to show is that the first CT scan was read as normal," said Podell, who also is a rig consultant for the Houston Texans, of the NFL. "After the first concussion there was no clue of any significant injury.
Women Suffer Postpartum Depression
Women Suffer Postpartum Depression.
Having a longer pregnancy leave reduces a woman's jeopardize of postpartum depression, new research shows. The findings suggest that the climactic 12 weeks of maternity leave given to American mothers under federal law may be inadequate, according to the University of Maryland researchers. "In the United States, most working women are back to fashion soon after giving birth, with the lion's share not taking more than three months of leave," study leader Dr Rada Dagher said in a university message release. "But our study showed that women who return to work sooner than six months after childbirth have an increased gamble of postpartum depressive symptoms," added Dagher, an assistant professor of vigour services administration at the School of Public Health.
In the year after giving birth, about 13 percent of mothers knowledge postpartum depression, which can cause serious symptoms similar to clinical depression. This consider included more than 800 women in Minnesota who were followed for a year after they gave birth. About 7 percent of the mothers went back to develop within six weeks, 46 percent by 12 weeks, and 87 percent by six months.
Having a longer pregnancy leave reduces a woman's jeopardize of postpartum depression, new research shows. The findings suggest that the climactic 12 weeks of maternity leave given to American mothers under federal law may be inadequate, according to the University of Maryland researchers. "In the United States, most working women are back to fashion soon after giving birth, with the lion's share not taking more than three months of leave," study leader Dr Rada Dagher said in a university message release. "But our study showed that women who return to work sooner than six months after childbirth have an increased gamble of postpartum depressive symptoms," added Dagher, an assistant professor of vigour services administration at the School of Public Health.
In the year after giving birth, about 13 percent of mothers knowledge postpartum depression, which can cause serious symptoms similar to clinical depression. This consider included more than 800 women in Minnesota who were followed for a year after they gave birth. About 7 percent of the mothers went back to develop within six weeks, 46 percent by 12 weeks, and 87 percent by six months.
Wednesday 15 January 2020
In Any Case, And Age, The Helmet Will Make The Race Safer
In Any Case, And Age, The Helmet Will Make The Race Safer.
As summer approaches and many Americans quail to dust off their bikes, blades and assorted motorized vehicles, the nation's predicament unit doctors are trying to unqualified public attention toward the importance of wearing safety helmets to prevent serious brain injury. "People are riding bicycles, motorcycles and ATVs all-terrain vehicles more often at this ease of year," Dr Angela Gardner, president of the American College of Emergency Physicians (ACEP), said in a communication release. She stressed that bourgeoisie need to get in the habit of wearing a certified safety helmet, because it only takes one distressing crash to end a life or cause serious life-altering brain injuries.
Citing National Highway Transportation Safety Administration (NHTSA) statistics, the ACEP experts note that every year more than 300000 children are rushed to the difficulty worry as a result of injuries sustained while riding a bike. Wearing a helmet that meets Consumer Product Safety Commission standards could ease this figure by more than two-thirds, the combine suggests.
But children aren't the only ones who need to wear helmets. In fact, older riders merit for 75 percent of bicycle injury deaths, the ACEP noted. Among bicyclists of all ages, 540000 endeavour emergency care each year as a result of an accident, and 67000 of these patients allow head injuries. About 40 percent experience head trauma so acute that hospitalization is required.
A properly fitted helmet can prevent brain injury 90 percent of the time, according to the NHTSA, and if all bicyclists between the ages of 4 and 15 wore a helmet, between 39000 and 45000 proceed injuries could be prevented each year. With May designated as motorcycle refuge month, the ACEP is also highlighting the benefits of helmet use middle motorcyclists. "Helmet use is the single most distinguished factor in people surviving motorcycle crashes," Gardner stated in the news release. "They depreciate the risk of head, brain and facial injury among motorcyclists of all ages and blast severities".
As summer approaches and many Americans quail to dust off their bikes, blades and assorted motorized vehicles, the nation's predicament unit doctors are trying to unqualified public attention toward the importance of wearing safety helmets to prevent serious brain injury. "People are riding bicycles, motorcycles and ATVs all-terrain vehicles more often at this ease of year," Dr Angela Gardner, president of the American College of Emergency Physicians (ACEP), said in a communication release. She stressed that bourgeoisie need to get in the habit of wearing a certified safety helmet, because it only takes one distressing crash to end a life or cause serious life-altering brain injuries.
Citing National Highway Transportation Safety Administration (NHTSA) statistics, the ACEP experts note that every year more than 300000 children are rushed to the difficulty worry as a result of injuries sustained while riding a bike. Wearing a helmet that meets Consumer Product Safety Commission standards could ease this figure by more than two-thirds, the combine suggests.
But children aren't the only ones who need to wear helmets. In fact, older riders merit for 75 percent of bicycle injury deaths, the ACEP noted. Among bicyclists of all ages, 540000 endeavour emergency care each year as a result of an accident, and 67000 of these patients allow head injuries. About 40 percent experience head trauma so acute that hospitalization is required.
A properly fitted helmet can prevent brain injury 90 percent of the time, according to the NHTSA, and if all bicyclists between the ages of 4 and 15 wore a helmet, between 39000 and 45000 proceed injuries could be prevented each year. With May designated as motorcycle refuge month, the ACEP is also highlighting the benefits of helmet use middle motorcyclists. "Helmet use is the single most distinguished factor in people surviving motorcycle crashes," Gardner stated in the news release. "They depreciate the risk of head, brain and facial injury among motorcyclists of all ages and blast severities".
Alleria Closely Associated To The Use Of Products From Fast Foods
Alleria Closely Associated To The Use Of Products From Fast Foods.
Kids who feed-bag rakishly food three or more times a week are disposed to to have more severe allergic reactions, a large new international study suggests. These comprise bouts of asthma, eczema and hay fever (rhinitis). And although the study doesn't confirm that those burgers, chicken snacks and fries cause these problems, the evidence of an association is compelling, researchers say. "The mull over adds to a growing body of evidence of the possible harms of fast foods," said work co-author Hywel Williams, a professor of dermato-epidemiology at the University of Nottingham, in England.
So "Whether the fact we have found is strong enough to recommend a reduction of fast food intake for those with allergies is a matter of debate". These discovery are important because this is the largest study to date on allergies in young people across the sphere and the findings are remarkably consistent globally for both boys and girls and regardless of family income. "If true, the findings have big consumers health implications given that these allergic disorders appear to be on the increase and because indecorously food is so popular".
However, Williams cautioned that fast food might not be causing these problems. "It could be due to other factors linked to behavior that we have not measured, or it could be due to biases that come to pass in studies that measure disease and ask about anterior food intake". In addition, this association between fast foods and severe allergies does not irresistibly mean that eating less fast food will reduce the severity of disease of asthma, hay fever or eczema (an itchy pelt disorder).
The report was published in the Jan 14, 2013 online point of Thorax. Williams and colleagues collected data on more than 319000 teens venerable 13 and 14 from 51 countries and more than 181000 kids aged 6 and 7 from 31 countries. All of the children were say of a single study on child asthma and allergies.
Kids and their parents were asked about whether they suffered from asthma or runny or blocked nose along with itchy and aqueous eyes and eczema. Participants also described in item what they ate during the week. Fast food was linked to those conditions in both older and younger children.
Kids who feed-bag rakishly food three or more times a week are disposed to to have more severe allergic reactions, a large new international study suggests. These comprise bouts of asthma, eczema and hay fever (rhinitis). And although the study doesn't confirm that those burgers, chicken snacks and fries cause these problems, the evidence of an association is compelling, researchers say. "The mull over adds to a growing body of evidence of the possible harms of fast foods," said work co-author Hywel Williams, a professor of dermato-epidemiology at the University of Nottingham, in England.
So "Whether the fact we have found is strong enough to recommend a reduction of fast food intake for those with allergies is a matter of debate". These discovery are important because this is the largest study to date on allergies in young people across the sphere and the findings are remarkably consistent globally for both boys and girls and regardless of family income. "If true, the findings have big consumers health implications given that these allergic disorders appear to be on the increase and because indecorously food is so popular".
However, Williams cautioned that fast food might not be causing these problems. "It could be due to other factors linked to behavior that we have not measured, or it could be due to biases that come to pass in studies that measure disease and ask about anterior food intake". In addition, this association between fast foods and severe allergies does not irresistibly mean that eating less fast food will reduce the severity of disease of asthma, hay fever or eczema (an itchy pelt disorder).
The report was published in the Jan 14, 2013 online point of Thorax. Williams and colleagues collected data on more than 319000 teens venerable 13 and 14 from 51 countries and more than 181000 kids aged 6 and 7 from 31 countries. All of the children were say of a single study on child asthma and allergies.
Kids and their parents were asked about whether they suffered from asthma or runny or blocked nose along with itchy and aqueous eyes and eczema. Participants also described in item what they ate during the week. Fast food was linked to those conditions in both older and younger children.
Some Medicines Purchased Via The Internet Can Be Dangerous
Some Medicines Purchased Via The Internet Can Be Dangerous.
Internet-based companies buy and sell them, men persist in to buy them and experts continue to apprise of the dangers of counterfeit drugs for erectile dysfunction. A new study, conducted in South Korea and slated for giving Monday at the American Urological Association annual meeting in San Francisco, finds that not only can these duplication drugs be contaminated, they may contain too much of the active ingredient or none at all. The drugs could especially be menacing for men with hypertension or heart disease, the study found.
The message? Stay away from non-prescription erectile dysfunction (ED) drugs, the experts say. "There are lots of rip-offs," said Dr John Morley, cicerone of geriatrics and acting chief of endocrinology at Saint Louis University. "There's still a lot of deposition that many of the things you buy off the Internet without going through a regular dispensary might appear cheaper or better but they're usually not and they usually don't work".
Drugs known as phosphodiesterase type 5 inhibitors (PDE5Is) are worn widely by men with erectile dysfunction - and sometimes by those without the condition. Perhaps the best known of the caste are sildenafil (Viagra) and tadalafil (Cialis). Since it was developed in 1998, the demand for these and similar products - legitimate or not - has mushroomed.
Internet-based companies buy and sell them, men persist in to buy them and experts continue to apprise of the dangers of counterfeit drugs for erectile dysfunction. A new study, conducted in South Korea and slated for giving Monday at the American Urological Association annual meeting in San Francisco, finds that not only can these duplication drugs be contaminated, they may contain too much of the active ingredient or none at all. The drugs could especially be menacing for men with hypertension or heart disease, the study found.
The message? Stay away from non-prescription erectile dysfunction (ED) drugs, the experts say. "There are lots of rip-offs," said Dr John Morley, cicerone of geriatrics and acting chief of endocrinology at Saint Louis University. "There's still a lot of deposition that many of the things you buy off the Internet without going through a regular dispensary might appear cheaper or better but they're usually not and they usually don't work".
Drugs known as phosphodiesterase type 5 inhibitors (PDE5Is) are worn widely by men with erectile dysfunction - and sometimes by those without the condition. Perhaps the best known of the caste are sildenafil (Viagra) and tadalafil (Cialis). Since it was developed in 1998, the demand for these and similar products - legitimate or not - has mushroomed.
Heart Risk For Elderly People Increases When Sleep Apnea
Heart Risk For Elderly People Increases When Sleep Apnea.
The snoring and breathing disturbances of beauty sleep apnea may be more than just a nuisance, with a late study linking the get to higher risks for heart failure and heart disease in middle-aged and older men. However, the deliberate over found no correlation between sleep apnea and coronary heart disease in women, or in men older than 70.
And "The vital here is that there is a lot of undiagnosed sleep apnea, and that, at least in men, it is associated with the phenomenon of coronary heart disease and heart failure. Only about 10 percent of catch forty winks apnea cases are diagnosed," said Dr Daniel Gottlieb, associate professor of medicine, Boston University School of Medicine. Gottlieb esteemed that while the jump in heart gamble was noteworthy, it was not as large as that seen in previous clinic-based studies of sleep apnea because the participants were drawn from a filthy community-based population.
According to background information in the study, sleep apnea sufferers awaken feverishly during the night struggling to breathe, often experiencing a shot of blood pressure- raising adrenaline. Most often, they go fist back to sleep, unaware of what happened. But the awakenings are repeated, sometimes up to 30 times an hour, depriving the sufferer of dynamic oxygen and sound sleep.
The research is published online July 12 in Circulation. In the study, almost 2000 men and about 2500 women - all released of verve problems at the beginning of the research - were recorded as they slept using polysomnograms, which premeditated the presence and severity of sleep apnea as calibrated on the Apnea-Hypopnea Index. About half had no symptoms of zizz apnea, the team found, while half had mild, moderate or severe symptoms.
Participants were then contacted at various times from 1998 to the irrevocable follow-up in April 2006. During that time, 473 cardiac events occurred, including 185 boldness attacks, 212 heart bypass operations, and 76 deaths. There were also 308 cases of centre failure; of these 144 people also had a nucleus attack.
The snoring and breathing disturbances of beauty sleep apnea may be more than just a nuisance, with a late study linking the get to higher risks for heart failure and heart disease in middle-aged and older men. However, the deliberate over found no correlation between sleep apnea and coronary heart disease in women, or in men older than 70.
And "The vital here is that there is a lot of undiagnosed sleep apnea, and that, at least in men, it is associated with the phenomenon of coronary heart disease and heart failure. Only about 10 percent of catch forty winks apnea cases are diagnosed," said Dr Daniel Gottlieb, associate professor of medicine, Boston University School of Medicine. Gottlieb esteemed that while the jump in heart gamble was noteworthy, it was not as large as that seen in previous clinic-based studies of sleep apnea because the participants were drawn from a filthy community-based population.
According to background information in the study, sleep apnea sufferers awaken feverishly during the night struggling to breathe, often experiencing a shot of blood pressure- raising adrenaline. Most often, they go fist back to sleep, unaware of what happened. But the awakenings are repeated, sometimes up to 30 times an hour, depriving the sufferer of dynamic oxygen and sound sleep.
The research is published online July 12 in Circulation. In the study, almost 2000 men and about 2500 women - all released of verve problems at the beginning of the research - were recorded as they slept using polysomnograms, which premeditated the presence and severity of sleep apnea as calibrated on the Apnea-Hypopnea Index. About half had no symptoms of zizz apnea, the team found, while half had mild, moderate or severe symptoms.
Participants were then contacted at various times from 1998 to the irrevocable follow-up in April 2006. During that time, 473 cardiac events occurred, including 185 boldness attacks, 212 heart bypass operations, and 76 deaths. There were also 308 cases of centre failure; of these 144 people also had a nucleus attack.
Saturday 11 January 2020
The Relationship Between Asthma And Chronic Nasal Congestion
The Relationship Between Asthma And Chronic Nasal Congestion.
A redone Swedish office shows that severe asthma seems to be more common than previously believed. It also reports that those afflicted by it have a higher mastery of blocked or runny noses, a possible initials that physicians should pay more attention to nasal congestion and similar issues. In the study, researchers surveyed 30000 woman in the street from the west of Sweden and asked about their health, including whether they had physician-diagnosed asthma, took asthma medication, and if so, what lenient of symptoms they experienced.
And "This is the first patch that the prevalence of severe asthma has been estimated in a population study, documenting that approximately 2 percent of the citizens in the West Sweden is showing signs of severe asthma," study co-author Jan Lotvall, professor at Sahlgrenska Academy's Krefting Research Center, said in a newsflash release from the University of Gothenburg. "This argues that more unembroidered forms of asthma are far more common than previously believed, and that trim care professionals should pay extra attention to patients with such symptoms".
A redone Swedish office shows that severe asthma seems to be more common than previously believed. It also reports that those afflicted by it have a higher mastery of blocked or runny noses, a possible initials that physicians should pay more attention to nasal congestion and similar issues. In the study, researchers surveyed 30000 woman in the street from the west of Sweden and asked about their health, including whether they had physician-diagnosed asthma, took asthma medication, and if so, what lenient of symptoms they experienced.
And "This is the first patch that the prevalence of severe asthma has been estimated in a population study, documenting that approximately 2 percent of the citizens in the West Sweden is showing signs of severe asthma," study co-author Jan Lotvall, professor at Sahlgrenska Academy's Krefting Research Center, said in a newsflash release from the University of Gothenburg. "This argues that more unembroidered forms of asthma are far more common than previously believed, and that trim care professionals should pay extra attention to patients with such symptoms".
Eating The Correct Ratio Of Omega-3 DHA And EPA Can Help Alleviate Depression
Eating The Correct Ratio Of Omega-3 DHA And EPA Can Help Alleviate Depression.
Omega-3 fatty acids may ease alleviate indentation but only when a unusual type of fatty acid called DHA is used in the right ratio with another fatty acid known as EPA, a redesigned study suggests. The researchers analyzed the results of some 15 above-named controlled clinical trials on the use of omega-3s - commonly found in oily fish or in fish unguent supplements - to treat depressed people. They found that when used by itself, DHA (docosahexaenoic acid) only did not seem to offer any benefit.
However, DHA combined with a rather high portion of EPA (eicosapentenoic acid) did improve depressive symptoms. "Preparations with some EPA had some consistent antidepressant effects, while preparations of unmixed DHA had no antidepressant effects," said lead study architect Dr John Davis, a professor of psychiatry at the University of Illinois at Chicago. "I don't of we can prove it beyond a shadow of a doubt, but there is now evidence from a number of double-blind studies that suggest mixed DHA/EPA has antidepressant properties, whether by itself or given along with unwritten antidepressants".
The study, funded by the US National Institutes of Health, was designed as a meta-analysis, in which researchers merge the results of multiple prior studies. The findings were slated for donation Thursday at the American College of Neuropsychopharmacology meeting in Miami.
Davis noted the next stage should be to test the anti-depressant effect of the omega-3 fatty acid combination in a large population to affirm a dose range. Prior research on the effectiveness of omega-3 fattys acids against depression has been mixed, with one new randomized, placebo-controlled clinical trial in the Journal of the American Medical Association, for example, concluding that taking 800 milligrams of DHA everyday did not help ward off depression in pregnant women.
Omega-3 fatty acids may ease alleviate indentation but only when a unusual type of fatty acid called DHA is used in the right ratio with another fatty acid known as EPA, a redesigned study suggests. The researchers analyzed the results of some 15 above-named controlled clinical trials on the use of omega-3s - commonly found in oily fish or in fish unguent supplements - to treat depressed people. They found that when used by itself, DHA (docosahexaenoic acid) only did not seem to offer any benefit.
However, DHA combined with a rather high portion of EPA (eicosapentenoic acid) did improve depressive symptoms. "Preparations with some EPA had some consistent antidepressant effects, while preparations of unmixed DHA had no antidepressant effects," said lead study architect Dr John Davis, a professor of psychiatry at the University of Illinois at Chicago. "I don't of we can prove it beyond a shadow of a doubt, but there is now evidence from a number of double-blind studies that suggest mixed DHA/EPA has antidepressant properties, whether by itself or given along with unwritten antidepressants".
The study, funded by the US National Institutes of Health, was designed as a meta-analysis, in which researchers merge the results of multiple prior studies. The findings were slated for donation Thursday at the American College of Neuropsychopharmacology meeting in Miami.
Davis noted the next stage should be to test the anti-depressant effect of the omega-3 fatty acid combination in a large population to affirm a dose range. Prior research on the effectiveness of omega-3 fattys acids against depression has been mixed, with one new randomized, placebo-controlled clinical trial in the Journal of the American Medical Association, for example, concluding that taking 800 milligrams of DHA everyday did not help ward off depression in pregnant women.
Thursday 9 January 2020
Vaccination Protects Against Influenza
Vaccination Protects Against Influenza.
US strength officials would like every American superannuated 6 months and older to get a flu vaccine, and on Thursday they produced statistics they deliberate should convince everyone to get vaccinated. "In the 2012-2013 flu season, vaccinations prevented at least 6,6 million cases of flu-associated illness. They also prevented some 3,2 million kith and kin from whereas their doctor and 79000 hospitalizations," Dr Tom Frieden, director of the US Centers for Disease Control and Prevention, said during a c noontide press briefing. The benefits of vaccination seen in 2012-2013 were greater than the CDC had seen before and were attributable to the harshness of the season.
So "Last year was a relatively stiff season. Even with those hospitalizations prevented, there were still about 381000 flu-associated hospitalizations. This is higher than we have seen during many flu seasons". During the end flu season, there were some 31,8 million influenza-associated illnesses and 14,4 million doctors visits for flu, according a CDC communication in the Dec 13, 2013 exit of the Morbidity and Mortality Weekly Report. Frieden said the best way to be protected from the flu is to be vaccinated.
Yet only 40 percent of Americans elderly 6 months and older had been vaccinated by early November. Flu across the boondocks is picking up and even greater activity is predicted in the coming weeks. Increased prevalence has been seen in the Southeast and in some states beyond that area. "We know that it will increase in the coming weeks and months, but we cannot augur where and when and how severe this year's flu season will be.
US strength officials would like every American superannuated 6 months and older to get a flu vaccine, and on Thursday they produced statistics they deliberate should convince everyone to get vaccinated. "In the 2012-2013 flu season, vaccinations prevented at least 6,6 million cases of flu-associated illness. They also prevented some 3,2 million kith and kin from whereas their doctor and 79000 hospitalizations," Dr Tom Frieden, director of the US Centers for Disease Control and Prevention, said during a c noontide press briefing. The benefits of vaccination seen in 2012-2013 were greater than the CDC had seen before and were attributable to the harshness of the season.
So "Last year was a relatively stiff season. Even with those hospitalizations prevented, there were still about 381000 flu-associated hospitalizations. This is higher than we have seen during many flu seasons". During the end flu season, there were some 31,8 million influenza-associated illnesses and 14,4 million doctors visits for flu, according a CDC communication in the Dec 13, 2013 exit of the Morbidity and Mortality Weekly Report. Frieden said the best way to be protected from the flu is to be vaccinated.
Yet only 40 percent of Americans elderly 6 months and older had been vaccinated by early November. Flu across the boondocks is picking up and even greater activity is predicted in the coming weeks. Increased prevalence has been seen in the Southeast and in some states beyond that area. "We know that it will increase in the coming weeks and months, but we cannot augur where and when and how severe this year's flu season will be.
Wednesday 8 January 2020
Painkillers Are One Of The Causes Of Death
Painkillers Are One Of The Causes Of Death.
Abuse of tranquillizing painkillers and other recipe drugs is a growing problem in the United States, and a leading doctors' series is urging members to exercise tighter control on the medications. The American College of Physicians (ACP) says its recommended changes will compel it tougher for prescription drugs - painkillers such as Oxycontin and Vicodin, as well as drugs occupied for sleep problems and weight loss - to be ill-treated or diverted for sale on the street. Prescription drug abuse may now be a prime cause of accidental demise in the United States, according to a recent tally of preliminary data from the US Centers for Disease Control and Prevention.
One 2010 survey, funded by the National Institute on Drug Abuse, found that 16 million Americans superannuated 12 and older had in use a prescription painkiller, sedative, tranquilizer or urge for purposes other than their medical care at least once in the prior year. One of the ACP's 10 recommendations highlighted the penury to educate doctors, patients and the public about the dangers of prescription drug abuse. The guidelines also suggested that doctors take to be the full range of available treatments before prescribing painkillers. Among the other recommendations.
Evidence-based, nonbinding guidelines should be developed to worker guide doctors' care decisions. A national prescription-drug-monitoring program should be created, so doctors and pharmacists can check almost identical programs in their own and neighboring states before writing and filling prescriptions for substances with high misapplication potential. Two experts said the ACP recommendations are welcome, but more must be done.
Abuse of tranquillizing painkillers and other recipe drugs is a growing problem in the United States, and a leading doctors' series is urging members to exercise tighter control on the medications. The American College of Physicians (ACP) says its recommended changes will compel it tougher for prescription drugs - painkillers such as Oxycontin and Vicodin, as well as drugs occupied for sleep problems and weight loss - to be ill-treated or diverted for sale on the street. Prescription drug abuse may now be a prime cause of accidental demise in the United States, according to a recent tally of preliminary data from the US Centers for Disease Control and Prevention.
One 2010 survey, funded by the National Institute on Drug Abuse, found that 16 million Americans superannuated 12 and older had in use a prescription painkiller, sedative, tranquilizer or urge for purposes other than their medical care at least once in the prior year. One of the ACP's 10 recommendations highlighted the penury to educate doctors, patients and the public about the dangers of prescription drug abuse. The guidelines also suggested that doctors take to be the full range of available treatments before prescribing painkillers. Among the other recommendations.
Evidence-based, nonbinding guidelines should be developed to worker guide doctors' care decisions. A national prescription-drug-monitoring program should be created, so doctors and pharmacists can check almost identical programs in their own and neighboring states before writing and filling prescriptions for substances with high misapplication potential. Two experts said the ACP recommendations are welcome, but more must be done.
Rheumatoid Arthritis And Shingles
Rheumatoid Arthritis And Shingles.
The newest medications old to scrutinize autoimmune diseases such as rheumatoid arthritis don't appear to raise the risk of developing shingles, experimental research indicates. There has been concern that these medications, called anti-tumor necrosis factor (anti-TNF) drugs, might prolong the chances of a shingles infection (also known as herpes zoster) because they create by suppressing a part of the immune system that causes the autoimmune attack. "These are commonly in use drugs for people with rheumatoid arthritis and other autoimmune diseases, and the issue was whether or not they increased the risk of shingles.
We found there is no increased hazard when using these drugs, which was reassuring," said study author Dr Kevin Winthrop, friend professor of infectious disease and public health and preventive medicine at Oregon Health and Science University in Portland. Results of the contemplate are published in the March 6 issue of the Journal of the American Medical Association.
Shingles is a paramount concern for people with autoimmune conditions, particularly occupy who are older and more at risk for developing shingles in general. Shingles is caused when the same virus that causes chickenpox is reactivated. The symptoms of shingles, however, are often far more genuine than chickenpox. It typically starts with a ardent or tingling pain, which is followed by the appearance of fluid-filled blisters, according to the US National Institutes of Neurological Disorders and Stroke.
Shingles soreness can vary from mild to so severe that even the lightest touch causes excessive pain. People who have rheumatoid arthritis already have an increased risk of shingles, although Winthrop said it's not specifically clear why. It may be due to older age, or it may have something to do with the disease itself. Rheumatoid arthritis and other autoimmune conditions are treated with many unlike medications that help dampen the immune set and, hopefully, the autoimmune attack.
The newest medications old to scrutinize autoimmune diseases such as rheumatoid arthritis don't appear to raise the risk of developing shingles, experimental research indicates. There has been concern that these medications, called anti-tumor necrosis factor (anti-TNF) drugs, might prolong the chances of a shingles infection (also known as herpes zoster) because they create by suppressing a part of the immune system that causes the autoimmune attack. "These are commonly in use drugs for people with rheumatoid arthritis and other autoimmune diseases, and the issue was whether or not they increased the risk of shingles.
We found there is no increased hazard when using these drugs, which was reassuring," said study author Dr Kevin Winthrop, friend professor of infectious disease and public health and preventive medicine at Oregon Health and Science University in Portland. Results of the contemplate are published in the March 6 issue of the Journal of the American Medical Association.
Shingles is a paramount concern for people with autoimmune conditions, particularly occupy who are older and more at risk for developing shingles in general. Shingles is caused when the same virus that causes chickenpox is reactivated. The symptoms of shingles, however, are often far more genuine than chickenpox. It typically starts with a ardent or tingling pain, which is followed by the appearance of fluid-filled blisters, according to the US National Institutes of Neurological Disorders and Stroke.
Shingles soreness can vary from mild to so severe that even the lightest touch causes excessive pain. People who have rheumatoid arthritis already have an increased risk of shingles, although Winthrop said it's not specifically clear why. It may be due to older age, or it may have something to do with the disease itself. Rheumatoid arthritis and other autoimmune conditions are treated with many unlike medications that help dampen the immune set and, hopefully, the autoimmune attack.
Very Loud Music Can Cause Hearing Loss In Adolescence
Very Loud Music Can Cause Hearing Loss In Adolescence.
Over the finish two decades hearing sacrifice due to "recreational" noise exposure such as blaring blackjack music has risen among adolescent girls, and now approaches levels previously seen only amid adolescent boys, a new study suggests. And teens as a whole are increasingly exposed to snazzy noises that could place their long-term auditory health in jeopardy, the researchers added. "In the '80s and dawn '90s young men experienced this kind of hearing damage in greater numbers, undoubtedly as a reflection - of what young men and young women have traditionally done for farm and fun," noted study lead author Elisabeth Henderson, an MD-candidate in Harvard Medical School's School of Public Health in Boston.
And "This means that boys have usually been faced with a greater caste of risk in the form of occupational noise exposure, fire alarms, lawn mowers, that sympathetic of thing. But now we're seeing that young women are experiencing this same level of damage, too". Henderson and her colleagues piece their findings in the Dec 27, 2010 online version of Pediatrics.
To explore the risk for hearing damage among teens, the authors analyzed the results of audiometric testing conducted centre of 4,310 adolescents between the ages of 12 and 19, all of whom participated in the US National Health and Nutrition Examination Surveys. Comparing booming noise uncovering across two periods of time (from 1988 to 1994 and from 2005 to 2006), the line-up determined that the degree of teen hearing loss had generally remained relatively stable. But there was one exception: teen girls.
Between the two investigate periods, hearing loss due to loud disturbance exposure had gone up among adolescent girls, from 11,6 percent to 16,7 percent - a plain that had previously been observed solely among adolescent boys. When asked about their past day's activities, look at participants revealed that their overall exposure to loud noise and/or their use of headphones for music-listening had rocketed up, from just under 20 percent in the overdue 1980s and early 1990s to nearly 35 percent of adolescents in 2005-2006.
Over the finish two decades hearing sacrifice due to "recreational" noise exposure such as blaring blackjack music has risen among adolescent girls, and now approaches levels previously seen only amid adolescent boys, a new study suggests. And teens as a whole are increasingly exposed to snazzy noises that could place their long-term auditory health in jeopardy, the researchers added. "In the '80s and dawn '90s young men experienced this kind of hearing damage in greater numbers, undoubtedly as a reflection - of what young men and young women have traditionally done for farm and fun," noted study lead author Elisabeth Henderson, an MD-candidate in Harvard Medical School's School of Public Health in Boston.
And "This means that boys have usually been faced with a greater caste of risk in the form of occupational noise exposure, fire alarms, lawn mowers, that sympathetic of thing. But now we're seeing that young women are experiencing this same level of damage, too". Henderson and her colleagues piece their findings in the Dec 27, 2010 online version of Pediatrics.
To explore the risk for hearing damage among teens, the authors analyzed the results of audiometric testing conducted centre of 4,310 adolescents between the ages of 12 and 19, all of whom participated in the US National Health and Nutrition Examination Surveys. Comparing booming noise uncovering across two periods of time (from 1988 to 1994 and from 2005 to 2006), the line-up determined that the degree of teen hearing loss had generally remained relatively stable. But there was one exception: teen girls.
Between the two investigate periods, hearing loss due to loud disturbance exposure had gone up among adolescent girls, from 11,6 percent to 16,7 percent - a plain that had previously been observed solely among adolescent boys. When asked about their past day's activities, look at participants revealed that their overall exposure to loud noise and/or their use of headphones for music-listening had rocketed up, from just under 20 percent in the overdue 1980s and early 1990s to nearly 35 percent of adolescents in 2005-2006.
Doctors Strongly Recommend That All Pregnant Women To Have A Blood Test For HIV
Doctors Strongly Recommend That All Pregnant Women To Have A Blood Test For HIV.
A babe born two-and-a-half years ago in Mississippi with HIV is the basic casing of a so-called "functional cure" of the infection, researchers announced Sunday. Standard tests can no longer spot any traces of the AIDS-causing virus even though the child has discontinued HIV medication. "We allow this is the first well-documented case of a functional cure," said look lead author Dr Deborah Persaud, associate professor of pediatrics in the class of infectious diseases at Johns Hopkins Children's Center in Baltimore. The finding was presented Sunday at the Conference on Retroviruses and Opportunistic Infections, in Atlanta.
The lass was not part of a study but, instead, the beneficiary of an unexpected and partly unplanned cycle of events that - once confirmed and replicated in a strict study - might help more children who are born with HIV or who at risk of contracting HIV from their parent eradicate the virus from their body. Normally, mothers infected with HIV take antiretroviral drugs that can almost murder the odds of the virus being transferred to the baby. If a mother doesn't be familiar with her HIV status or hasn't been treated for other reasons, the baby is given "prophylactic" drugs at birth while awaiting the results of tests to infer his or her HIV status.
This can take four to six weeks to complete. If the tests are positive, the child starts HIV drug treatment. The fuss over of the baby born in Mississippi didn't know she was HIV-positive until the time of delivery.
But in this case, both the primary and confirmatory tests on the baby were able to be completed within one day, allowing the baby to be started on HIV medicine treatment within the first 30 hours of life. "Most of our kids don't get picked up that early". As expected, the baby's "viral load" - detectable levels of HIV - decreased progressively until it was no longer detectable at 29 days of age.
Theoretically, this young gentleman (doctors aren't disclosing the gender) would have bewitched the medications for the lay of his or her life, said the researchers, who included doctors from the University of Massachusetts Medical School and the University of Mississippi Medical Center. Instead, the toddler stayed on the regimen for only 18 months before dropping out of the medical combination and discontinuing the drugs.
Ten months after stopping treatment, however, the youth was again seen by doctors who were surprised to find no HIV virus or HIV antibodies with customary tests. Ultrasensitive tests did detect infinitesimal traces of viral DNA and RNA in the blood. But the virus was not replicating - a influentially unusual occurrence given that drugs were no longer being administered, the researchers said.
A babe born two-and-a-half years ago in Mississippi with HIV is the basic casing of a so-called "functional cure" of the infection, researchers announced Sunday. Standard tests can no longer spot any traces of the AIDS-causing virus even though the child has discontinued HIV medication. "We allow this is the first well-documented case of a functional cure," said look lead author Dr Deborah Persaud, associate professor of pediatrics in the class of infectious diseases at Johns Hopkins Children's Center in Baltimore. The finding was presented Sunday at the Conference on Retroviruses and Opportunistic Infections, in Atlanta.
The lass was not part of a study but, instead, the beneficiary of an unexpected and partly unplanned cycle of events that - once confirmed and replicated in a strict study - might help more children who are born with HIV or who at risk of contracting HIV from their parent eradicate the virus from their body. Normally, mothers infected with HIV take antiretroviral drugs that can almost murder the odds of the virus being transferred to the baby. If a mother doesn't be familiar with her HIV status or hasn't been treated for other reasons, the baby is given "prophylactic" drugs at birth while awaiting the results of tests to infer his or her HIV status.
This can take four to six weeks to complete. If the tests are positive, the child starts HIV drug treatment. The fuss over of the baby born in Mississippi didn't know she was HIV-positive until the time of delivery.
But in this case, both the primary and confirmatory tests on the baby were able to be completed within one day, allowing the baby to be started on HIV medicine treatment within the first 30 hours of life. "Most of our kids don't get picked up that early". As expected, the baby's "viral load" - detectable levels of HIV - decreased progressively until it was no longer detectable at 29 days of age.
Theoretically, this young gentleman (doctors aren't disclosing the gender) would have bewitched the medications for the lay of his or her life, said the researchers, who included doctors from the University of Massachusetts Medical School and the University of Mississippi Medical Center. Instead, the toddler stayed on the regimen for only 18 months before dropping out of the medical combination and discontinuing the drugs.
Ten months after stopping treatment, however, the youth was again seen by doctors who were surprised to find no HIV virus or HIV antibodies with customary tests. Ultrasensitive tests did detect infinitesimal traces of viral DNA and RNA in the blood. But the virus was not replicating - a influentially unusual occurrence given that drugs were no longer being administered, the researchers said.
Treatment Of Heart Attack And Stroke In Certified Hospitals
Treatment Of Heart Attack And Stroke In Certified Hospitals.
Around the nation, hospitals pass on to themselves as "stroke centers of excellence" or "chest bore centers," the substance being those facilities offer top-notch care for stroke and heart attacks. But stylish programs for certifying, accrediting or recognizing hospitals as providers of the best cardiovascular or stroke care are falling short, according to an American Heart Association/American Stroke Association advisory. "Right now, it's not always sheer what is just a marketing duration and what actually truly distinguishes the quality of a center," said Dr Gregg Fonarow, an American Heart Association spokesman and professor of cardiovascular medication at the University of California, Los Angeles.
A look at of the available data found no clear relationship between having a festive designation as a heart attack or stroke care center and the care the hospitals provide or, even more important, how patients fare. To variation that, the American Heart Association and the American Stroke Association are jointly developing a inclusive stroke and cardiovascular care certification program that should go through as a national standard.
The goal is to help patients, insurers and others have more reliable data about where they are most likely to receive the most up-to-date, evidence-based care available. "There is a value to having a trusted origin develop a certification program that clinicians, insurers and the public can use to understand which hospitals are providing uncommon cardiovascular and stroke care, including achieving high-quality outcomes".
The program, which will take from about two years to develop and will likely be done in partnership with other major medical organizations, will cover exigency situations such as heart attack and stroke, but also heart failure management and coronary bypass surgery. The admonitory is published online Nov 12, 2010 and in the Dec 7, 2010 language issue of Circulation.
Typically, recognition and certification programs require that hospitals put certain procedures in place, but they don't praepostor how well hospitals are adhering to the practices or whether patient outcomes are improving precedent author of the advisory. And those are the better certification programs. Other self-proclaimed "centers of excellence" may unmistakably be terms dreamed up by marketing departments.
Around the nation, hospitals pass on to themselves as "stroke centers of excellence" or "chest bore centers," the substance being those facilities offer top-notch care for stroke and heart attacks. But stylish programs for certifying, accrediting or recognizing hospitals as providers of the best cardiovascular or stroke care are falling short, according to an American Heart Association/American Stroke Association advisory. "Right now, it's not always sheer what is just a marketing duration and what actually truly distinguishes the quality of a center," said Dr Gregg Fonarow, an American Heart Association spokesman and professor of cardiovascular medication at the University of California, Los Angeles.
A look at of the available data found no clear relationship between having a festive designation as a heart attack or stroke care center and the care the hospitals provide or, even more important, how patients fare. To variation that, the American Heart Association and the American Stroke Association are jointly developing a inclusive stroke and cardiovascular care certification program that should go through as a national standard.
The goal is to help patients, insurers and others have more reliable data about where they are most likely to receive the most up-to-date, evidence-based care available. "There is a value to having a trusted origin develop a certification program that clinicians, insurers and the public can use to understand which hospitals are providing uncommon cardiovascular and stroke care, including achieving high-quality outcomes".
The program, which will take from about two years to develop and will likely be done in partnership with other major medical organizations, will cover exigency situations such as heart attack and stroke, but also heart failure management and coronary bypass surgery. The admonitory is published online Nov 12, 2010 and in the Dec 7, 2010 language issue of Circulation.
Typically, recognition and certification programs require that hospitals put certain procedures in place, but they don't praepostor how well hospitals are adhering to the practices or whether patient outcomes are improving precedent author of the advisory. And those are the better certification programs. Other self-proclaimed "centers of excellence" may unmistakably be terms dreamed up by marketing departments.
Tuesday 7 January 2020
The Presence Of A Few Extra Pounds In Man Reduces The Risk Of Sudden Death
The Presence Of A Few Extra Pounds In Man Reduces The Risk Of Sudden Death.
A uncharted worldwide opinion reveals a surprising pattern: while obesity increases the risk of dying early, being slightly overweight reduces it. These studies included almost 3 million adults from around the world, yet the results were remarkably consistent, the authors of the scrutiny noted. "For populate with a medical condition, survival is slight better for people who are slightly heavier," said study author Katherine Flegal, a older research scientist at the US Centers for Disease Control and Prevention's National Center for Health Statistics.
Several factors may narrative for this finding. "Maybe heavier people present to the doctor earlier, or get screened more often. Heavier bourgeoisie may be more likely to be treated according to guidelines, or fat itself may be cardioprotective, or someone who is heavier might be more resilient and better able to summer-house a shock to their system". The report was published Jan. 2 in the Journal of the American Medical Association.
For the study, Flegal's body collected data on more than 2,88 million kinsfolk included in 97 studies. These studies were done in the United States, Canada, Europe, Australia, China, Taiwan, Japan, Brazil, Israel, India and Mexico. The researchers looked at the participants' body miscellany index, or BMI, which is a extent of body fat that takes into narration a person's height and weight. Pooling the data from all the studies, the researchers found that compared with normal substance people, overweight people had a 6 percent lower risk of death.
Obese people, however, had an 18 percent higher chance of death. For those who were the least obese, the risk of eradication was 5 percent lower than for normal weight people, but for those who were the most obese the risk of death was 29 percent higher, the findings revealed. While the workroom found an association between weight and premature expiration risk, it did not prove a cause-and-effect relationship.
A uncharted worldwide opinion reveals a surprising pattern: while obesity increases the risk of dying early, being slightly overweight reduces it. These studies included almost 3 million adults from around the world, yet the results were remarkably consistent, the authors of the scrutiny noted. "For populate with a medical condition, survival is slight better for people who are slightly heavier," said study author Katherine Flegal, a older research scientist at the US Centers for Disease Control and Prevention's National Center for Health Statistics.
Several factors may narrative for this finding. "Maybe heavier people present to the doctor earlier, or get screened more often. Heavier bourgeoisie may be more likely to be treated according to guidelines, or fat itself may be cardioprotective, or someone who is heavier might be more resilient and better able to summer-house a shock to their system". The report was published Jan. 2 in the Journal of the American Medical Association.
For the study, Flegal's body collected data on more than 2,88 million kinsfolk included in 97 studies. These studies were done in the United States, Canada, Europe, Australia, China, Taiwan, Japan, Brazil, Israel, India and Mexico. The researchers looked at the participants' body miscellany index, or BMI, which is a extent of body fat that takes into narration a person's height and weight. Pooling the data from all the studies, the researchers found that compared with normal substance people, overweight people had a 6 percent lower risk of death.
Obese people, however, had an 18 percent higher chance of death. For those who were the least obese, the risk of eradication was 5 percent lower than for normal weight people, but for those who were the most obese the risk of death was 29 percent higher, the findings revealed. While the workroom found an association between weight and premature expiration risk, it did not prove a cause-and-effect relationship.
Study Of Helmets With Face Shields
Study Of Helmets With Face Shields.
Adding expression shields to soldiers' helmets could truncate brain damage resulting from explosions, which account for more than half of all combat-related injuries unremitting by US troops, a new study suggests. Using computer models to simulate battlefield blasts and their chattels on brain tissue, researchers learned that the face is the strongest pathway through which an explosion's pressure waves reach the brain. According to the US Department of Defense, about 130000 US repair members deployed in Afghanistan and Iraq have sustained blast-induced injurious brain injury (TBI) from explosions.
The addition of a face shield made with transparent armor statistics to the advanced combat helmets (ACH) worn by most troops significantly impeded direct curse waves to the face, mitigating brain injury, said lead researcher Raul Radovitzky, an confidant professor at the Massachusetts Institute of Technology (MIT). "We tried to assess the physics of the problem, but also the biological and clinical responses, and bind it all together," said Radovitzky, who is also associate chief honcho of MIT's Institute for Soldier Nanotechnologies. "The key thing from our point of view is that we gnome the problem in the news and thought maybe we could make a contribution".
Researching the issue, Radovitzky created computer models by collaborating with David Moore, a neurologist at the Defense and Veterans Brain Injury Center at Walter Reed Army Medical Center in Washington, DC Moore old MRI scans to simulate features of the brain, and the two scientists compared how the brains would reply to a frontal destroy wave in three scenarios: a head with no helmet, a head wearing the ACH, and a prime minister wearing the ACH plus a face shield. The sophisticated computer models were able to fuse the force of blast waves with skull features such as the sinuses, cerebrospinal fluid, and the layers of gray and whey-faced matter in the brain. Results revealed that without the face shield, the ACH slightly delayed the burst wave's arrival but did not significantly lessen its effect on brain tissue. Adding a face shield, however, considerably reduced forces on the brain.
Adding expression shields to soldiers' helmets could truncate brain damage resulting from explosions, which account for more than half of all combat-related injuries unremitting by US troops, a new study suggests. Using computer models to simulate battlefield blasts and their chattels on brain tissue, researchers learned that the face is the strongest pathway through which an explosion's pressure waves reach the brain. According to the US Department of Defense, about 130000 US repair members deployed in Afghanistan and Iraq have sustained blast-induced injurious brain injury (TBI) from explosions.
The addition of a face shield made with transparent armor statistics to the advanced combat helmets (ACH) worn by most troops significantly impeded direct curse waves to the face, mitigating brain injury, said lead researcher Raul Radovitzky, an confidant professor at the Massachusetts Institute of Technology (MIT). "We tried to assess the physics of the problem, but also the biological and clinical responses, and bind it all together," said Radovitzky, who is also associate chief honcho of MIT's Institute for Soldier Nanotechnologies. "The key thing from our point of view is that we gnome the problem in the news and thought maybe we could make a contribution".
Researching the issue, Radovitzky created computer models by collaborating with David Moore, a neurologist at the Defense and Veterans Brain Injury Center at Walter Reed Army Medical Center in Washington, DC Moore old MRI scans to simulate features of the brain, and the two scientists compared how the brains would reply to a frontal destroy wave in three scenarios: a head with no helmet, a head wearing the ACH, and a prime minister wearing the ACH plus a face shield. The sophisticated computer models were able to fuse the force of blast waves with skull features such as the sinuses, cerebrospinal fluid, and the layers of gray and whey-faced matter in the brain. Results revealed that without the face shield, the ACH slightly delayed the burst wave's arrival but did not significantly lessen its effect on brain tissue. Adding a face shield, however, considerably reduced forces on the brain.
In The USA Scientists Have Found The New Causes Of Glaucoma
In The USA Scientists Have Found The New Causes Of Glaucoma.
Glucosamine supplements that millions of Americans select to balm treat up on and knee osteoarthritis may have an unexpected side effect: They may increase risk for developing glaucoma, a scanty new study of older adults suggests in May 2013. Glaucoma occurs when there is an proliferation of intraocular pressure (IOP) or pressure inside the eye. Left untreated, glaucoma is one of the unsurpassed causes of blindness.
In the new study of 17 people, whose average age was 76 years, 11 participants had their optic pressure measured before, during and after taking glucosamine supplements. The other six had their liking pressure measured while and after they took the supplements. Overall, pressure inside the sidelong glance was higher when participants were taking glucosamine, but did return to normal after they stopped taking these supplements, the study showed.
So "This swatting shows a reversible effect of these changes, which is reassuring," wrote researchers led by Dr Ryan Murphy at the University of New England College of Osteopathic Medicine in Biddeford, Maine. "However, the likelihood that constant damage can result from prolonged use of glucosamine supplementation is not eliminated. Monitoring IOP in patients choosing to extend with glucosamine may be indicated".
Exactly how glucosamine supplements could affect power inside the eye is not fully understood, but several theories exist. For example, glucosamine is a harbinger for molecules called glycosaminoglycans, which may elevate eye pressure. The findings are published online May 23 as a delving letter in JAMA Ophthalmology.
Glucosamine supplements that millions of Americans select to balm treat up on and knee osteoarthritis may have an unexpected side effect: They may increase risk for developing glaucoma, a scanty new study of older adults suggests in May 2013. Glaucoma occurs when there is an proliferation of intraocular pressure (IOP) or pressure inside the eye. Left untreated, glaucoma is one of the unsurpassed causes of blindness.
In the new study of 17 people, whose average age was 76 years, 11 participants had their optic pressure measured before, during and after taking glucosamine supplements. The other six had their liking pressure measured while and after they took the supplements. Overall, pressure inside the sidelong glance was higher when participants were taking glucosamine, but did return to normal after they stopped taking these supplements, the study showed.
So "This swatting shows a reversible effect of these changes, which is reassuring," wrote researchers led by Dr Ryan Murphy at the University of New England College of Osteopathic Medicine in Biddeford, Maine. "However, the likelihood that constant damage can result from prolonged use of glucosamine supplementation is not eliminated. Monitoring IOP in patients choosing to extend with glucosamine may be indicated".
Exactly how glucosamine supplements could affect power inside the eye is not fully understood, but several theories exist. For example, glucosamine is a harbinger for molecules called glycosaminoglycans, which may elevate eye pressure. The findings are published online May 23 as a delving letter in JAMA Ophthalmology.
Testing A New Experimental Drug To Raise Good Cholesterol Level
Testing A New Experimental Drug To Raise Good Cholesterol Level.
An conjectural poison that raises HDL, or "good," cholesterol seems to have passed an sign hurdle by proving safe in preliminary trials. Although the trial was primarily designed to overlook at safety, researchers scheduled to present the finding Wednesday at the American Heart Association's annual assignation in Chicago also report that anacetrapib raised HDL cholesterol by 138 percent and slap in the face LDL, HDL's evil twin, almost in half. "We saw very encouraging reductions in clinical events," said Dr Christopher Cannon, assume command author of the study, which also appears in the Nov 18, 2010 exit of the New England Journal of Medicine.
A big study to seal the results would take four to five years to complete so the drug is still years away from market who is a cardiologist with Brigham and Women's Hospital in Boston. Other experts are intrigued by the findings, but note that the check out is still in very ahead stages. "There are a lot of people in the prevention/lipid field that are simultaneously excited and leery," said Dr Howard Weintraub, clinical concert-master of the Center for the Prevention of Cardiovascular Disease at NYU Langone Medical Center in New York City.
Added Dr John C LaRosa, president of the State University of New York (SUNY) Downstate Medical Center in New York City: "It's very prodromic but it's material because the final drug out of the barrel of this type was not a success. This looks match a better drug, but it's not definitive by any means. Don't take this to the bank".
LaRosa was referring to torcetrapib, which, get off on anacetrapib, belongs to the class of drugs known as cholesterol ester take protein (CETP) inhibitors. A large trial on torcetrapib was killed after investigators found an increased jeopardy of death and other cardiovascular outcomes. "I would be more excited about anacetrapib if I hadn't seen what happened to its cousin torcetrapib. Torcetrapib raised HDL astoundingly but that was completely neutralized by the development in cardiovascular events".
An conjectural poison that raises HDL, or "good," cholesterol seems to have passed an sign hurdle by proving safe in preliminary trials. Although the trial was primarily designed to overlook at safety, researchers scheduled to present the finding Wednesday at the American Heart Association's annual assignation in Chicago also report that anacetrapib raised HDL cholesterol by 138 percent and slap in the face LDL, HDL's evil twin, almost in half. "We saw very encouraging reductions in clinical events," said Dr Christopher Cannon, assume command author of the study, which also appears in the Nov 18, 2010 exit of the New England Journal of Medicine.
A big study to seal the results would take four to five years to complete so the drug is still years away from market who is a cardiologist with Brigham and Women's Hospital in Boston. Other experts are intrigued by the findings, but note that the check out is still in very ahead stages. "There are a lot of people in the prevention/lipid field that are simultaneously excited and leery," said Dr Howard Weintraub, clinical concert-master of the Center for the Prevention of Cardiovascular Disease at NYU Langone Medical Center in New York City.
Added Dr John C LaRosa, president of the State University of New York (SUNY) Downstate Medical Center in New York City: "It's very prodromic but it's material because the final drug out of the barrel of this type was not a success. This looks match a better drug, but it's not definitive by any means. Don't take this to the bank".
LaRosa was referring to torcetrapib, which, get off on anacetrapib, belongs to the class of drugs known as cholesterol ester take protein (CETP) inhibitors. A large trial on torcetrapib was killed after investigators found an increased jeopardy of death and other cardiovascular outcomes. "I would be more excited about anacetrapib if I hadn't seen what happened to its cousin torcetrapib. Torcetrapib raised HDL astoundingly but that was completely neutralized by the development in cardiovascular events".
Skiing Prolongs Life
Skiing Prolongs Life.
Hitting the slopes soon? A unexplored writing-room suggests that's a good idea, because skiing and snowboarding holidays can boost your overall happiness. Researchers surveyed 279 visitors at three principal ski resorts in South Korea. Of those people, 126 were skiers, 112 were snowboarders and 41 did both. Participants worn out an mean of 4,5 days at a resort, and 90 percent visited ski resorts less than five times a season.
Hitting the slopes soon? A unexplored writing-room suggests that's a good idea, because skiing and snowboarding holidays can boost your overall happiness. Researchers surveyed 279 visitors at three principal ski resorts in South Korea. Of those people, 126 were skiers, 112 were snowboarders and 41 did both. Participants worn out an mean of 4,5 days at a resort, and 90 percent visited ski resorts less than five times a season.
People Often Die In Their Sleep
People Often Die In Their Sleep.
People with doze apnea and hard-to-control drunk blood pressure may see their blood pressure drop if they treat the catnap disorder, Spanish researchers report. Continuous positive airway pressure (CPAP) is the orthodox treatment for sleep apnea, a condition characterized by disrupted breathing during sleep. The drop disorder has been linked to high blood pressure. Patients in this study were taking three or more drugs to tone down their blood pressure, in addition to having sleep apnea.
Participants who used the CPAP device for 12 weeks reduced their diastolic blood compel (the bottom number in a blood pressure reading) and improved their overall nighttime blood pressure, the researchers found. "The popularity of sleep apnea in patients with uncompliant high blood pressure is very high," said lead researcher Dr Miguel-Angel Martinez-Garcia, from the Polytechnic University Hospital in Valencia. "This forty winks apnea therapy increases the probability of recovering the normal nocturnal blood pressure pattern.
Patients with resistant great in extent blood pressure should undergo a sleep study to rule out obstructive sleep apnea, Martinez-Garcia said. "If the resolute has sleep apnea, he should be treated with CPAP and undergo blood compression monitoring". The report, published in the Dec 11, 2013 issue of the Journal of the American Medical Association, was partly funded by Philips-Respironics, maker of the CPAP combination used in the study.
The CPAP organized whole consists of a motor that pushes air through a tube connected to a mask that fits over the patient's announce and nose. The device keeps the airway from closing, and thus allows interminable sleep. Sleep apnea is a common disorder. The pauses in breathing that patients know-how can last from a few seconds to minutes and they can occur 30 times or more an hour.
People with doze apnea and hard-to-control drunk blood pressure may see their blood pressure drop if they treat the catnap disorder, Spanish researchers report. Continuous positive airway pressure (CPAP) is the orthodox treatment for sleep apnea, a condition characterized by disrupted breathing during sleep. The drop disorder has been linked to high blood pressure. Patients in this study were taking three or more drugs to tone down their blood pressure, in addition to having sleep apnea.
Participants who used the CPAP device for 12 weeks reduced their diastolic blood compel (the bottom number in a blood pressure reading) and improved their overall nighttime blood pressure, the researchers found. "The popularity of sleep apnea in patients with uncompliant high blood pressure is very high," said lead researcher Dr Miguel-Angel Martinez-Garcia, from the Polytechnic University Hospital in Valencia. "This forty winks apnea therapy increases the probability of recovering the normal nocturnal blood pressure pattern.
Patients with resistant great in extent blood pressure should undergo a sleep study to rule out obstructive sleep apnea, Martinez-Garcia said. "If the resolute has sleep apnea, he should be treated with CPAP and undergo blood compression monitoring". The report, published in the Dec 11, 2013 issue of the Journal of the American Medical Association, was partly funded by Philips-Respironics, maker of the CPAP combination used in the study.
The CPAP organized whole consists of a motor that pushes air through a tube connected to a mask that fits over the patient's announce and nose. The device keeps the airway from closing, and thus allows interminable sleep. Sleep apnea is a common disorder. The pauses in breathing that patients know-how can last from a few seconds to minutes and they can occur 30 times or more an hour.
A Tan Is Still Admired By Ignoring The Danger Of Cancer
A Tan Is Still Admired By Ignoring The Danger Of Cancer.
Despite significant concerns about pellicle cancer, a the better of Americans nevertheless regard that having a tan is an attractive, desirable and healthy look, a new national survey finds. The enumerate was conducted by the American Academy of Dermatology (AAD) in January, and included just over 7100 men and women nationwide. "Our enquiry highlighted the contradictory feelings that many people have about tanning - they love the way a tan looks but are concerned about skin cancer, which is estimated to choose about one in five Americans in their lifetime," Dr Zoe D Draelos, a dermatologist and consulting professor at Duke University School of Medicine in Durham NC, said in a telecast release.
So "What they may not net is that no matter whether you tan or burn, a tan from the sun or tanning beds damages the peel and can cause wrinkles, age spots and skin cancer. The challenge is changing the long-standing attitudes about tanning to correlate with people's proficiency about skin cancer".
Despite significant concerns about pellicle cancer, a the better of Americans nevertheless regard that having a tan is an attractive, desirable and healthy look, a new national survey finds. The enumerate was conducted by the American Academy of Dermatology (AAD) in January, and included just over 7100 men and women nationwide. "Our enquiry highlighted the contradictory feelings that many people have about tanning - they love the way a tan looks but are concerned about skin cancer, which is estimated to choose about one in five Americans in their lifetime," Dr Zoe D Draelos, a dermatologist and consulting professor at Duke University School of Medicine in Durham NC, said in a telecast release.
So "What they may not net is that no matter whether you tan or burn, a tan from the sun or tanning beds damages the peel and can cause wrinkles, age spots and skin cancer. The challenge is changing the long-standing attitudes about tanning to correlate with people's proficiency about skin cancer".
Monday 6 January 2020
Depression Plus Diabetes Kills Women
Depression Plus Diabetes Kills Women.
Women pain from both diabetes and unhappiness have a greater risk of dying, especially from heart disease, a new study suggests. In fact, women with both conditions have a twofold increased peril of death, researchers say. "People with both conditions are at very hilarious risk of death," said lead researcher Dr Frank B Hu, a professor of nostrum at Harvard Medical School. "Those are double whammies". When males and females are afflicted by both diseases, these conditions can lead to a "vicious cycle. People with diabetes are more likely to be depressed, because they are under long-term psychosocial stress, which is associated with diabetes complications".
People with diabetes who are depressed are less no doubt to abduct care of themselves and effectively manage their diabetes. "That can lead to complications, which increase the risk of mortality". Hu stressed that it is signal to manage both the diabetes and the depression to lower the mortality risk. "It is reachable that these two conditions not only influence each other biologically, but also behaviorally".
Type 2 diabetes and depression are often allied to unhealthy lifestyles, including smoking, poor diet and lack of exercise, according to the researchers. In addition, gloominess may trigger changes in the nervous system that adversely affect the heart. The promulgate is published in the January, 2011 issue of the Archives of General Psychiatry.
Commenting on the study, Dr Luigi Meneghini, an collaborator professor of clinical medicine and director of the Eleanor and Joseph Kosow Diabetes Treatment Center at the Diabetes Research Institute of the University of Miami Miller School of Medicine, said the findings were not surprising. "The review highlights that there is a lustrous increase in jeopardize to your health and to your life when you have a combination of diabetes and depression".
Women pain from both diabetes and unhappiness have a greater risk of dying, especially from heart disease, a new study suggests. In fact, women with both conditions have a twofold increased peril of death, researchers say. "People with both conditions are at very hilarious risk of death," said lead researcher Dr Frank B Hu, a professor of nostrum at Harvard Medical School. "Those are double whammies". When males and females are afflicted by both diseases, these conditions can lead to a "vicious cycle. People with diabetes are more likely to be depressed, because they are under long-term psychosocial stress, which is associated with diabetes complications".
People with diabetes who are depressed are less no doubt to abduct care of themselves and effectively manage their diabetes. "That can lead to complications, which increase the risk of mortality". Hu stressed that it is signal to manage both the diabetes and the depression to lower the mortality risk. "It is reachable that these two conditions not only influence each other biologically, but also behaviorally".
Type 2 diabetes and depression are often allied to unhealthy lifestyles, including smoking, poor diet and lack of exercise, according to the researchers. In addition, gloominess may trigger changes in the nervous system that adversely affect the heart. The promulgate is published in the January, 2011 issue of the Archives of General Psychiatry.
Commenting on the study, Dr Luigi Meneghini, an collaborator professor of clinical medicine and director of the Eleanor and Joseph Kosow Diabetes Treatment Center at the Diabetes Research Institute of the University of Miami Miller School of Medicine, said the findings were not surprising. "The review highlights that there is a lustrous increase in jeopardize to your health and to your life when you have a combination of diabetes and depression".
Americans Rarely Write Wills
Americans Rarely Write Wills.
Most Americans do not deal with end-of-life issues and wishes, a original lessons indicates. Researchers analyzed data from nearly 8000 people who took break up in nationwide surveys conducted in 2009 and 2010, and found that only about 26 percent had completed an advance directive, also called a living will. There were significant associations between completing an go forward directive and age, income, knowledge and health status, according to the study in the January issue of the American Journal of Preventive Medicine.
Advance directives were more hackneyed among women, whites, married people and those who had a college degree or postgraduate training. People with advanced directives also were more inclined to to have a chronic disease or a regular source of care. "For raven and Hispanic respondents, advance directives were less frequent across all educational groups.
Most Americans do not deal with end-of-life issues and wishes, a original lessons indicates. Researchers analyzed data from nearly 8000 people who took break up in nationwide surveys conducted in 2009 and 2010, and found that only about 26 percent had completed an advance directive, also called a living will. There were significant associations between completing an go forward directive and age, income, knowledge and health status, according to the study in the January issue of the American Journal of Preventive Medicine.
Advance directives were more hackneyed among women, whites, married people and those who had a college degree or postgraduate training. People with advanced directives also were more inclined to to have a chronic disease or a regular source of care. "For raven and Hispanic respondents, advance directives were less frequent across all educational groups.
New Way To Treat Parkinson's Disease
New Way To Treat Parkinson's Disease.
Deep thought stimulation might staff improve the driving ability of people with Parkinson's disease, a new German ponder suggests. A deep brain stimulator is an implanted device that sends electrical impulses to the brain. With patients who have epilepsy, the stimulator is believed to farther down the risk of seizures, the researchers said. A driving simulator tested the abilities of 23 Parkinson's patients with a acute wit stimulator, 21 patients without the device and a control group of 21 people without Parkinson's.
Deep thought stimulation might staff improve the driving ability of people with Parkinson's disease, a new German ponder suggests. A deep brain stimulator is an implanted device that sends electrical impulses to the brain. With patients who have epilepsy, the stimulator is believed to farther down the risk of seizures, the researchers said. A driving simulator tested the abilities of 23 Parkinson's patients with a acute wit stimulator, 21 patients without the device and a control group of 21 people without Parkinson's.
Physicians In The USA Recommend To Make A Mammography To All Women
Physicians In The USA Recommend To Make A Mammography To All Women.
More than three years after disputable recent guidelines rejected bit annual mammograms for most women, women in all age groups continue to get yearly screenings, a unusual survey shows. In fact, mammogram rates actually increased overall, from 51,9 percent in 2008 to 53,6 percent in 2011, even though the lightly made rise was not considered statistically significant, according to the researchers from Brigham and Women's Hospital and Harvard Medical School. "There have been no significant changes in the proportion of screening mammograms surrounded by any age group, but in particular among women under ripen 50," said the study leader, Dr Lydia Pace, a global women's fettle fellow in the division of women's health at Brigham and Women's.
While the study did not look at the reasons for continued screening, the researchers speculated that conflicting recommendations from various maestro organizations may play a role. In 2009, the US Preventive Services Task Force, an maverick panel of experts, issued unknown guidelines that said women younger than 50 don't need routine annual mammograms and those 50 to 74 could get screened every two years. Before that, the commendation was that all women elderly 40 and older get mammograms every one to two years.
The recommendations ignited much controversy and renewed dispute about whether delayed screening would increase breast cancer mortality. Since then, organizations such as the American Cancer Society have adhered to the recommendations that women 40 and older be screened annually. To undergo what object the new task force recommendations have had, the researchers analyzed facts from almost 28000 women over a six-year period - before and after the new task force guidelines.
The women were responding to the National Health Interview Survey in 2005, 2008 and 2011, and were asked how often they got a mammogram for screening purposes. Across the ages, there was no decay in screenings, the researchers found. Among women 40 to 49, the rates rose slightly, from 46,1 percent in 2008 to 47,5 percent in 2011. Among women old 50 to 74, the rates also rose, from 57,2 percent in 2008 to 59,1 percent in 2011.
More than three years after disputable recent guidelines rejected bit annual mammograms for most women, women in all age groups continue to get yearly screenings, a unusual survey shows. In fact, mammogram rates actually increased overall, from 51,9 percent in 2008 to 53,6 percent in 2011, even though the lightly made rise was not considered statistically significant, according to the researchers from Brigham and Women's Hospital and Harvard Medical School. "There have been no significant changes in the proportion of screening mammograms surrounded by any age group, but in particular among women under ripen 50," said the study leader, Dr Lydia Pace, a global women's fettle fellow in the division of women's health at Brigham and Women's.
While the study did not look at the reasons for continued screening, the researchers speculated that conflicting recommendations from various maestro organizations may play a role. In 2009, the US Preventive Services Task Force, an maverick panel of experts, issued unknown guidelines that said women younger than 50 don't need routine annual mammograms and those 50 to 74 could get screened every two years. Before that, the commendation was that all women elderly 40 and older get mammograms every one to two years.
The recommendations ignited much controversy and renewed dispute about whether delayed screening would increase breast cancer mortality. Since then, organizations such as the American Cancer Society have adhered to the recommendations that women 40 and older be screened annually. To undergo what object the new task force recommendations have had, the researchers analyzed facts from almost 28000 women over a six-year period - before and after the new task force guidelines.
The women were responding to the National Health Interview Survey in 2005, 2008 and 2011, and were asked how often they got a mammogram for screening purposes. Across the ages, there was no decay in screenings, the researchers found. Among women 40 to 49, the rates rose slightly, from 46,1 percent in 2008 to 47,5 percent in 2011. Among women old 50 to 74, the rates also rose, from 57,2 percent in 2008 to 59,1 percent in 2011.
Military Suffer From Depression
Military Suffer From Depression.
Private contractors who worked in Afghanistan, Iraq and other brawl zones over the since two years have high rates of depression and post-traumatic burden disorder (PTSD), a new study finds. Researchers conducted an anonymous online appraisal of 660 contractors who had been deployed to a conflict zone at least once between early 2011 and early 2013, and found that 25 percent met the criteria for PTSD and 18 percent for depression. Half reported liquor misuse.
Despite these problems, few contractors received serve before or after deployment, according to the study by the RAND Corp, a nonprofit explore organization. Even though most of them had health insurance, only 28 percent of those with PTSD and 34 percent of those with hollow reported receiving mental health treatment in the previous 12 months. Many contractors also reported material health problems as a result of deployment, including traumatic intellect injuries, respiratory issues, back pain and hearing problems, the study authors pointed out in a RAND announcement release.
Private contractors who worked in Afghanistan, Iraq and other brawl zones over the since two years have high rates of depression and post-traumatic burden disorder (PTSD), a new study finds. Researchers conducted an anonymous online appraisal of 660 contractors who had been deployed to a conflict zone at least once between early 2011 and early 2013, and found that 25 percent met the criteria for PTSD and 18 percent for depression. Half reported liquor misuse.
Despite these problems, few contractors received serve before or after deployment, according to the study by the RAND Corp, a nonprofit explore organization. Even though most of them had health insurance, only 28 percent of those with PTSD and 34 percent of those with hollow reported receiving mental health treatment in the previous 12 months. Many contractors also reported material health problems as a result of deployment, including traumatic intellect injuries, respiratory issues, back pain and hearing problems, the study authors pointed out in a RAND announcement release.
Daily Long-Term Use Of Low-Dose Aspirin Reduces The Risk Of Death From Various Cancers
Daily Long-Term Use Of Low-Dose Aspirin Reduces The Risk Of Death From Various Cancers.
Long-term use of a ordinary low-dose aspirin dramatically cuts the danger of fading from a wide array of cancers, a new investigation reveals. Specifically, a British inspect team unearthed evidence that a low-dose aspirin (75 milligrams) captivated daily for at least five years brings about a 10 percent to 60 percent tear in fatalities depending on the type of cancer. The finding stems from a fresh analysis of eight studies involving more than 25,500 patients, which had from the outset been conducted to examine the protective potential of a low-dose aspirin regimen on cardiovascular disease.
The au courant observations follow prior research conducted by the same library team, which reported in October that a long-term regimen of low-dose aspirin appears to shave the endanger of dying from colorectal cancer by a third. "These findings provide the first proof in mortals that aspirin reduces deaths due to several common cancers," the study team noted in a news release.
But the study's model author, Prof. Peter Rothwell from John Radcliffe Hospital and the University of Oxford, stressed that "these results do not undignified that all adults should immediately start taking aspirin. They do exhibit major new benefits that have not previously been factored into guideline recommendations," he added, noting that "previous guidelines have rightly cautioned that in tonic middle-aged people, the small risk of bleeding on aspirin partly offsets the promote from prevention of strokes and heart attacks".
And "But the reductions in deaths due to several banal cancers will now alter this balance for many people," Rothwell suggested. Rothwell and his colleagues published their findings Dec 7, 2010 in the online printing of The Lancet. The on involved in the current review had been conducted for an average period of four to eight years.
Long-term use of a ordinary low-dose aspirin dramatically cuts the danger of fading from a wide array of cancers, a new investigation reveals. Specifically, a British inspect team unearthed evidence that a low-dose aspirin (75 milligrams) captivated daily for at least five years brings about a 10 percent to 60 percent tear in fatalities depending on the type of cancer. The finding stems from a fresh analysis of eight studies involving more than 25,500 patients, which had from the outset been conducted to examine the protective potential of a low-dose aspirin regimen on cardiovascular disease.
The au courant observations follow prior research conducted by the same library team, which reported in October that a long-term regimen of low-dose aspirin appears to shave the endanger of dying from colorectal cancer by a third. "These findings provide the first proof in mortals that aspirin reduces deaths due to several common cancers," the study team noted in a news release.
But the study's model author, Prof. Peter Rothwell from John Radcliffe Hospital and the University of Oxford, stressed that "these results do not undignified that all adults should immediately start taking aspirin. They do exhibit major new benefits that have not previously been factored into guideline recommendations," he added, noting that "previous guidelines have rightly cautioned that in tonic middle-aged people, the small risk of bleeding on aspirin partly offsets the promote from prevention of strokes and heart attacks".
And "But the reductions in deaths due to several banal cancers will now alter this balance for many people," Rothwell suggested. Rothwell and his colleagues published their findings Dec 7, 2010 in the online printing of The Lancet. The on involved in the current review had been conducted for an average period of four to eight years.
The USA Is Expected Outbreak Of The Virus Chikungunya (CHIKV)
The USA Is Expected Outbreak Of The Virus Chikungunya (CHIKV).
It's reachable that a crucial mosquito-borne virus - with no known vaccine or remedying - could migrate from Central Africa and Southeast Asia to the United States within a year, redesigned research suggests. The chances of a US outbreak of the Chikungunya virus (CHIKV) varies by period and geography, with those regions typified by longer stretches of warm weather facing longer periods of favourable risk, according to the researchers' new computer model. "The only way for this contagion to be transmitted is if a mosquito bites an infected human and a few days after that it bites a healthy individual, transmitting the virus," said contemplation lead author Diego Ruiz-Moreno, a postdoctoral associate in the jurisdiction of ecology and evolutionary biology at Cornell University in Ithaca, NY "The repetition of this series of events can lead to a disease outbreak".
And that, Ruiz-Moreno said, is where weather comes into the picture, with computer simulations revealing that the gamble of an outbreak rises when temperatures, and therefore mosquito populations, rise. The cramming analyzed possible outbreak scenarios in three US locales. In 2013, the New York department is set to face its highest risk for a CHIKV outbreak during the steamed up months of August and September, the analysis suggests.
By contrast, Atlanta's highest-risk period was identified as longer, beginning in June and sustained through September. Miami's consistent warm weather means the region faces a higher chance all year. "Warmer weather increases the length of the period of high risk," Ruiz-Moreno said. "This is outstandingly worrisome if we think of the effects of climate change over regular temperatures in the near future".
Ruiz-Moreno discussed his team's research - funded in part by the US National Institute for Food and Agriculture - in a brand-new issue of the journal PLoS Neglected Tropical Diseases. CHIKV was commencement identified in Tanzania in 1953, the authors noted, and the severe combined and muscle pain, fever, fatigue, headaches, rashes and nausea that can result are sometimes not with it with symptoms of dengue fever.
It's reachable that a crucial mosquito-borne virus - with no known vaccine or remedying - could migrate from Central Africa and Southeast Asia to the United States within a year, redesigned research suggests. The chances of a US outbreak of the Chikungunya virus (CHIKV) varies by period and geography, with those regions typified by longer stretches of warm weather facing longer periods of favourable risk, according to the researchers' new computer model. "The only way for this contagion to be transmitted is if a mosquito bites an infected human and a few days after that it bites a healthy individual, transmitting the virus," said contemplation lead author Diego Ruiz-Moreno, a postdoctoral associate in the jurisdiction of ecology and evolutionary biology at Cornell University in Ithaca, NY "The repetition of this series of events can lead to a disease outbreak".
And that, Ruiz-Moreno said, is where weather comes into the picture, with computer simulations revealing that the gamble of an outbreak rises when temperatures, and therefore mosquito populations, rise. The cramming analyzed possible outbreak scenarios in three US locales. In 2013, the New York department is set to face its highest risk for a CHIKV outbreak during the steamed up months of August and September, the analysis suggests.
By contrast, Atlanta's highest-risk period was identified as longer, beginning in June and sustained through September. Miami's consistent warm weather means the region faces a higher chance all year. "Warmer weather increases the length of the period of high risk," Ruiz-Moreno said. "This is outstandingly worrisome if we think of the effects of climate change over regular temperatures in the near future".
Ruiz-Moreno discussed his team's research - funded in part by the US National Institute for Food and Agriculture - in a brand-new issue of the journal PLoS Neglected Tropical Diseases. CHIKV was commencement identified in Tanzania in 1953, the authors noted, and the severe combined and muscle pain, fever, fatigue, headaches, rashes and nausea that can result are sometimes not with it with symptoms of dengue fever.
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