Cryoneedles A Possible Alternative To Botox In Fighting Against Wrinkles.
A fresh technology that for the meantime zaps away forehead wrinkles by freezing the nerves shows assurance in early clinical trials, researchers say. The technique, if at last approved by the US Food and Drug Administration, could provide an alternative to Botox and Dysport. Both are injectable forms of Botulinum toxin typeface A, a neurotoxin that, when injected in lesser quantities, temporarily paralyzes facial muscles, thereby reducing wrinkles. "It's a toxin-free other to treating unwanted lines and wrinkles, similar to what is being done with Botox and Dysport," said deliberate over co-author Francis Palmer, director of facial plastic surgery at the University of Southern California School of Medicine in Los Angeles.
And "From the antique clinical trials, this procedure - which its maker calls cryoneuromodulation - appears to have the same clinical efficacy and cover comparable to the existing techniques". Palmer is also consulting medical supervisor of MyoScience Inc, the Redwood City (California) - based circle developing the cryotechnology. The results of the clinical trials were to be presented Friday at an American Society for Laser Medicine and Surgery (ASLMS) congress in Grapevine, Texas.
To do the procedure, physicians use slight needles - "cryoprobes" - to deliver cold to nerves continual through the forehead, specifically the temporal branch of the frontal nerve. The cold freezes the nerve, which interrupts the gall signal and relaxes the muscle that causes vertical and horizontal forehead lines. Although the temerity quickly returns to normal body temperature, the cold temporarily "injures" the nerve, allowing the beckon to remain interrupted for some period of time after the patient leaves the office.
The manner does not permanently damage the nerve. Researchers said they are still refining the technique and could not say how crave the effect lasts, but it seems to be comparable to Botox, which works for about three to four months. Physicians would call for training to identify the nerve that should be targeted.
The 15-minute treatment is done using local anesthesia, according to the researchers. The around study only looks at forehead wrinkles; future research will study the conduct elsewhere on the face. For the study, researchers tried the technique on 31 people, all of whom had fewer wrinkles after two to eight injections. The most conventional side effects were headaches and incrustation redness.
The level of discomfort was comparable to that from Botox or fillers. But unlike Botox, which takes a few days to punt in, the effects of the cryotechnology are seen immediately, the researchers say. Because this investigate was presented at a medical meeting, the data and conclusions should be viewed as preliminary until published in a peer-reviewed journal.
Palmer said he didn't notice the new technology as a replacement for Botox, but instead as an alternative for grass roots who don't want an injection of a neurotoxin. The company will eventually seek FDA approval as a medical device. Palmer said the entourage might first seek approval in Europe.
Dr Brian Zelickson, an collaborator professor of dermatology at the University of Minnesota in Minneapolis, said the technique sounds promising, but needs more experiment with to determine how long results last and to make sure no lasting determination or muscle injury occurs that could cause permanent changes in sensation. He agreed that the toxin-free cosmetic modus operandi might win some followers.
So "Botox and Dysport are very easy, very quick, the patient satisfaction analysis is great and there are very few side effects," said Zelickson, incoming president of ASLMS. "It's a high shut out to leap over, but there are some people that don't like the concept of injecting Botulinum toxin into their bodies. If there were a form that could be done, that doesn't inject any chemical into the system and could yield the same results for the same duration, there is a bazaar for that" home page. According to the American Society for Aesthetic Plastic Surgery, Botox and Dysport injections cover their list of nonsurgical procedures.
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