New Genetic Marker For Autism And Schizophrenia

New Genetic Marker For Autism And Schizophrenia.
An foreign consortium of researchers has linked a regional unconventionality found in a specific chromosome to a significantly increased risk for both autism spectrum disorders (ASD) and schizophrenia. Although former work has indicated that genetic mutations action an important role in the risk of both disorders, this latest finding is the first to hone in on this specified abnormality, which takes the form of a wholesale absence of a certain sequence of genetic material. Individuals missing the chromosome 17 progression are about 14 times more likely to develop autism and schizophrenia, the check in team estimated.

And "We have uncovered a genetic variation that confers a very high chance for ASD, schizophrenia and neurodevelopmental disorders," study author Dr Daniel Moreno-De-Luca, a postdoctoral concomitant in the department of human genetics at Emory University in Atlanta, said in a university info release. Moreno-De-Luca further explained the significance of the finding by noting that this particular region, comprised of 15 genes, "is amid the 10 most frequent pathogenic recurrent genomic deletions identified in children with unexplained neurodevelopment impairments.

We credence in it also may increase risk for other psychiatric conditions such as bipolar disorder". He and his colleagues gunshot their findings in the Nov 4, 2010 online copy of the American Journal of Human Genetics.

Identification of this new genetic marker for autism and schizophrenia stemmed from peg away with about 23000 patients diagnosed with autism, developmental delay, intellectual disability or schizophrenia, 24 of whom had the chromosome 17 deletion. By contrast, middle a pool of nearly 52500 wholesome patients, none were found to be missing the genetic material, the investigators reported pillarder.com. The authors noted that last research had established that a mutation in one of the 15 missing genes in the newly identified sequence is a cause of both renal cysts and diabetes syndrome.