The Researchers Found That High Blood Sugar Impairs Brain Communication With The Nervous System

The Researchers Found That High Blood Sugar Impairs Brain Communication With The Nervous System.
A covert relationship between diabetes and a heightened chance of heart disease and sudden cardiac death has been spotted by researchers studying mice. In the novel study, published in the June 24, 2010 issue of the journal Neuron, the investigators found that high-priced blood sugar prevents critical communication between the brain and the autonomic concerned system, which controls involuntary activities in the body. "Diseases, such as diabetes, that disturb the function of the autonomic skittish system cause a wide range of abnormalities that include poor control of blood pressure, cardiac arrhythmias and digestive problems," major author Dr Ellis Cooper, of McGill University in Montreal, explained in a low-down release from the journal's publisher. "In most people with diabetes, the malfunction of the autonomic highly-strung system adversely affects their quality of life and shortens enthusiasm expectancy".

For the study, Cooper and his colleagues used mice with a form of diabetes to examine electrical conspicuous transmission from the brain to autonomic neurons. This communication occurs at synapses, which are petite gaps between neurons where electrical signals are relayed cell-to-cell via chemical neurotransmitters.

So "In well individuals, synaptic transmission in the autonomic nervous system is strong and stable; however, if synapses on these neurons malfunction due to some disability process, the link between the nervous system and the periphery becomes disrupted," Cooper said in the rumour release. The researchers found that, in mice, spaced out blood sugar elevates reactive molecules that contain the oxygen atom (called reactive oxygen species) in autonomic neurons.

This chemical coin inactivates the neurotransmitter receptors at these synapses. "Our till provides a new explanation for diabetic-induced disruptions of the autonomic nervous system. This synaptic gloominess is apparent as early as one week after the onset of diabetes and becomes more painful over time" view homepage. It's important to note that animal studies, while an important part of the scientific process, often go into receivership to yield similar results in humans.