A New Alternative To Warfarin As A Blood Thinner

A New Alternative To Warfarin As A Blood Thinner.
A imaginative blood thinner might be a reasonable alternative to warfarin (Coumadin), the standard for decades to deal with patients with the dangerous heart rhythm disorder known as atrial fibrillation. In investigate presented Monday at the American Heart Association's annual meeting in Chicago, researchers reported that rivaroxaban (Xarelto) proved to be just as trustworthy as warfarin, and possibly superior. Rivaroxaban also reduced the hazard of serious bleeding events, which is the most troubling side effect of warfarin.

Dabigatran (Pradaxa), another newer-generation blood thinner, was approved by the US Food and Drug Administration to scrutinize atrial fibrillation persist month. This latest study was sponsored by Johnson & Johnson Pharmaceutical Research & Development and Bayer Healthcare, the makers of rivaroxaban.

Warfarin is the principal support for the treatment of patients with atrial fibrillation, which affects some 2,2 million Americans. During atrial fibrillation, the heart's two petite loftier chambers - called the atria - quiver rather than stir methodically, raising the risk of blood clots and eventually a stroke. The drug is remarkable in reducing the risk of stroke, but it has significant drawbacks, including the bleeding risk and difficulties with dosing and monitoring.

And "In October of 2006, the FDA US Food and Drug Administration issued a black-box sign for warfarin due to a growing thanks of its hazards in routine clinical practice," said Dr Elaine Hylek, who spoke at a Monday story conference on the findings, although she was not involved with the mammoth study. "The provision for monitoring has relegated millions of people to no therapy or ineffective therapy because of shortage of access to monitoring and an intense search for an alternative with more predictable dose responses".

Hylek is an associate professor of cure-all at Boston University School of Medicine and reported ties with several pharmaceutical companies. The most recent trial, which scientists said was the largest of its kind, involved an international collaboration of researchers in 45 countries, 1215 medical centers and 14269 patients with atrial fibrillation who had already had a accomplishment or who had danger factors for a stroke.