Vaccination Against Tuberculosis Prevents Multiple Sclerosis.
A vaccine normally worn to short-circuit the respiratory illness tuberculosis also might help prevent the development of multiple sclerosis, a blight of the central nervous system, a new study suggests Dec 2013. In grass roots who had a first episode of symptoms that indicated they might develop multiple sclerosis (MS), an injection of the tuberculosis vaccine lowered the probability of developing MS, Italian researchers report. "It is feasible that a safe, handy and cheap approach will be available immediately following the first episode of symptoms suggesting MS," said studio lead author Dr Giovanni Ristori, of the Center for Experimental Neurological Therapies at Sant'Andrea Hospital in Rome.
But, the swat authors cautioned that much more scrutiny is needed before the tuberculosis vaccine could possibly be used against multiple sclerosis. In people with MS, the unaffected system attacks healthy cells in the central nervous system, which includes the perspicacity and spinal cord. One of the first signs of MS is what's known as "clinically secluded syndrome". Symptoms include numbing and problems with vision, hearing and balance.
About half of relations who experience clinically isolated syndrome develop MS within two years. The study, published online Dec. 4 in the log Neurology, included 73 people who'd had clinically lonely syndrome. Thirty-three received the tuberculosis vaccine and the remaining 40 were given a placebo, or dummy, injection. The tuberculosis vaccine is a active vaccine called the Bacille Calmette-Guerin vaccine, which isn't extensively used in the United States.
The same vaccine also is being studied as a treatment for specimen 1 diabetes. The participants had monthly MRI scans of their brains for the first six months of the review to look for lesions associated with multiple sclerosis. For the next year, they received a narcotize (interferon beta-1a) given to people with MS. After that, they received the treatment recommended by their own neurologist. After five years, the participants were reexamined to glom if they had developed MS.