New Research In The Treatment Of Cancer Of Immune System.
New explore provides more display that treating certain lymphoma patients with an valuable drug over the long term helps them go longer without symptoms. But the drug, called rituximab (Rituxan), does not seem to significantly development life span, raising questions about whether it's worth taking. People with lymphoma who are in maintenance treatment "really need a discussion with their oncologist," said Dr Steven T Rosen, cicerone of the Robert H Lurie Comprehensive Cancer Center at Northwestern University in Chicago. The contemplation involved people with follicular lymphoma, one of the milder forms of non-Hodgkin lymphoma, a locution that refers to cancers of the immune system.
Though it can be fatal, most individuals live for at least 10 years after diagnosis. There has been debate over whether people with the disease should kill Rituxan as maintenance therapy after their initial chemotherapy. In the study, which was funded in part by F Hoffmann-La Roche, a pharmaceutical throng that sells Rituxan, roughly half of the 1,019 participants took Rituxan, and the others did not. All at one time had taken the drug right after receiving chemotherapy.
In the next three years, the scan found, people taking the drug took longer, on average, to expand symptoms. Three-quarters of them made it to the three-year mark without progression of their illness, compared with about 58 percent of those who didn't snitch the drug. But the death rate over three years remained about the same, according to the report, published online Dec 21 2010 in The Lancet.
Tuesday, 24 December 2019
In Different Life Years Self-Esteem Varies Considerably
In Different Life Years Self-Esteem Varies Considerably.
Self-esteem increases as the crowd fructify older, but dips when people are in their 60s, although those who make more money and are healthier favour to retain better views of themselves, researchers have found. In the study, published in the April copy of the Journal of Personality and Social Psychology, researchers surveyed 3617 US adults grey 25 to 104, trying to reach all of them four times between 1986 and 2002.
So "Self-esteem is interrelated to better health, less criminal behavior, lower levels of depression and, overall, greater ascendancy in life," the study's lead author, Ulrich Orth, said in a news release from the American Psychological Association. "Therefore, it's urgent to learn more about how the average person's self-esteem changes over time".
Young commonality had the lowest self-esteem, but it grew as people aged, peaking at about age 60. Women had cut self-esteem than men, on average, until they reached their 80s and 90s, the study authors found.
Wealth and salubriousness played major roles in boosting self-esteem, especially in older people. "Specifically, we found that masses who have higher incomes and better health in later life tend to maintain their self-esteem as they age. We cannot be informed for certain that more wealth and better health directly lead to higher self-esteem, but it does appear to be linked in some way.
For example, it is imaginable that wealth and health are related to feeling more independent and better able to contribute to one's descent and society, which in turn bolsters self-esteem". As to why self-esteem peaks in middle-age and then often drops as populace get older, the researchers suggested several theories.
Self-esteem increases as the crowd fructify older, but dips when people are in their 60s, although those who make more money and are healthier favour to retain better views of themselves, researchers have found. In the study, published in the April copy of the Journal of Personality and Social Psychology, researchers surveyed 3617 US adults grey 25 to 104, trying to reach all of them four times between 1986 and 2002.
So "Self-esteem is interrelated to better health, less criminal behavior, lower levels of depression and, overall, greater ascendancy in life," the study's lead author, Ulrich Orth, said in a news release from the American Psychological Association. "Therefore, it's urgent to learn more about how the average person's self-esteem changes over time".
Young commonality had the lowest self-esteem, but it grew as people aged, peaking at about age 60. Women had cut self-esteem than men, on average, until they reached their 80s and 90s, the study authors found.
Wealth and salubriousness played major roles in boosting self-esteem, especially in older people. "Specifically, we found that masses who have higher incomes and better health in later life tend to maintain their self-esteem as they age. We cannot be informed for certain that more wealth and better health directly lead to higher self-esteem, but it does appear to be linked in some way.
For example, it is imaginable that wealth and health are related to feeling more independent and better able to contribute to one's descent and society, which in turn bolsters self-esteem". As to why self-esteem peaks in middle-age and then often drops as populace get older, the researchers suggested several theories.
Monday, 23 December 2019
Americans Continue To Get New Medical Insurance
Americans Continue To Get New Medical Insurance.
As the sure viewpoint of the Affordable Care Act, sometimes called "Obamacare," begins, a new crack shows that more than 45 million Americans still don't have health insurance. As troubling as that issue may seem, it represents only 14,6 percent of the population and it is a modest decline from the past few years, according to the news from the US Centers for Disease Control and Prevention. "To no one's surprise, the most recent statistics on health insurance coverage from the National Center for Health Statistics demonstrate that there is not yet much impact from the implementation of the Affordable Care Act," said Dr Don McCanne, a elder health procedure fellow at Physicians for a National Health Program.
McCanne, who had no part in the study, said he expects the rates of the uninsured to smidgin further as the Affordable Care Act is fully enacted in 2014. "Over the next year or two, because of the mandate requiring individuals to be insured, it can be anticipated that insured rates will increase, only with increases in confidential coverage through the exchange plans and increases in Medicaid coverage in those states that are cooperating with the federal government". In the report, published in the December offspring of the CDC's NCHS Data Brief, the numbers of the uninsured diverse by age.
In the first half of 2013, 7 percent of children under 18 had no vigorousness insurance. Among those with insurance, 41 percent had a public strength plan, and nearly 53 percent had private health insurance, according to the report. As for those aged 18 to 64, about one-fifth were uninsured, about two-thirds had hidden health insurance and nearly 17 percent had manifest health insurance. Insurance coverage also varied by state, the researchers found.
As the sure viewpoint of the Affordable Care Act, sometimes called "Obamacare," begins, a new crack shows that more than 45 million Americans still don't have health insurance. As troubling as that issue may seem, it represents only 14,6 percent of the population and it is a modest decline from the past few years, according to the news from the US Centers for Disease Control and Prevention. "To no one's surprise, the most recent statistics on health insurance coverage from the National Center for Health Statistics demonstrate that there is not yet much impact from the implementation of the Affordable Care Act," said Dr Don McCanne, a elder health procedure fellow at Physicians for a National Health Program.
McCanne, who had no part in the study, said he expects the rates of the uninsured to smidgin further as the Affordable Care Act is fully enacted in 2014. "Over the next year or two, because of the mandate requiring individuals to be insured, it can be anticipated that insured rates will increase, only with increases in confidential coverage through the exchange plans and increases in Medicaid coverage in those states that are cooperating with the federal government". In the report, published in the December offspring of the CDC's NCHS Data Brief, the numbers of the uninsured diverse by age.
In the first half of 2013, 7 percent of children under 18 had no vigorousness insurance. Among those with insurance, 41 percent had a public strength plan, and nearly 53 percent had private health insurance, according to the report. As for those aged 18 to 64, about one-fifth were uninsured, about two-thirds had hidden health insurance and nearly 17 percent had manifest health insurance. Insurance coverage also varied by state, the researchers found.
An Approved Vaccine To Treat Prostate Cancer Has Few Side Effects
An Approved Vaccine To Treat Prostate Cancer Has Few Side Effects.
The newly approved restorative prostate cancer vaccine, Provenge, is conservative and has few airs effects, a new study finds. In April, the US Food and Drug Administration approved the vaccine for use in men with advanced prostate cancer who had failed hormone therapy. "Provenge was approved based on both cover and clinical data," said prima donna researcher Dr Simon J Hall, bench of urology at Mount Sinai Medical Center in New York City.
This refuge data shows that there are very limited side effects. The superiority of the vaccine for patients with metastatic hormone-resistant prostate cancer is that it has fewer side stuff than chemotherapy, which is the only other treatment option for these patients. In addition, Provenge has improved survival over chemotherapy.
The mean survival time for men given Provenge is 4,5 months, although some patients saw their lives extended by two to three years. "This is a newly nearby treatment, with very limited standpoint effects, compared to anything else that a man would be considering in this state". Hall was to present the results on Monday at the American Urological Association annual convergence in San Francisco.
Data from four phase 3 trials, which included 904 men randomized to either Provenge or placebo, showed the vaccine extended survival, improved nobility of viability and had only mild side effects. In fact, more than 83 percent of the men who received Provenge were able to do appear as activities without any restrictions, the researchers noted.
The newly approved restorative prostate cancer vaccine, Provenge, is conservative and has few airs effects, a new study finds. In April, the US Food and Drug Administration approved the vaccine for use in men with advanced prostate cancer who had failed hormone therapy. "Provenge was approved based on both cover and clinical data," said prima donna researcher Dr Simon J Hall, bench of urology at Mount Sinai Medical Center in New York City.
This refuge data shows that there are very limited side effects. The superiority of the vaccine for patients with metastatic hormone-resistant prostate cancer is that it has fewer side stuff than chemotherapy, which is the only other treatment option for these patients. In addition, Provenge has improved survival over chemotherapy.
The mean survival time for men given Provenge is 4,5 months, although some patients saw their lives extended by two to three years. "This is a newly nearby treatment, with very limited standpoint effects, compared to anything else that a man would be considering in this state". Hall was to present the results on Monday at the American Urological Association annual convergence in San Francisco.
Data from four phase 3 trials, which included 904 men randomized to either Provenge or placebo, showed the vaccine extended survival, improved nobility of viability and had only mild side effects. In fact, more than 83 percent of the men who received Provenge were able to do appear as activities without any restrictions, the researchers noted.
Passive Smoking Increases The Risk Of Sinusitis
Passive Smoking Increases The Risk Of Sinusitis.
Exposure to secondhand smoke appears to sincerely foster the risk for chronic sinusitis, a new Canadian swotting has found. In fact, it might explain 40 percent of the cases of the condition, said muse about author Dr C Martin Tammemagi, a researcher at Brock University in Ontario. "The numbers surprised me somewhat. My imprecise impression was that public health agencies were strongly discouraging smoking and controlling secondhand smoke, and that governments in similarity were passing protective legislation to adjust peoples' exposure to secondhand smoke".
But his team found that more than 90 percent of those in the study who had hardened sinusitis and more than 84 percent of the comparison group, which did not have the condition, were exposed to secondhand smoke in following places. "To see that exposure to secondhand smoke was still common did surprise and alarm me".
The depraved effects of secondhand smoke have been well-documented, and experts know it contains more than 4,000 substances, including 50 or more known or suspected carcinogens and many basic irritants, according to Tammemagi. The identify with between secondhand smoke and sinusitis, however, has been little studied. "To date, there have not been any high-quality studies that have looked at this carefully" and then estimated the lines that smoke plays in the sinus problem.
In their study, the researchers evaluated reports of secondhand smoke danger in 306 nonsmokers who had chronic rhinosinusitis, defined as swelling of the nose or sinuses lasting 12 weeks or longer. The sinuses are cavities within the cheek bones, around the eyes and behind the nose that moisten and dribble air within the nasal cavity.
The researchers asked the participants about their risk to secondhand smoke for the five years before their diagnosis and then compared the responses with those of 306 consumers of similar age, sex and race who did not have the sinus problem. Those with sinusitis were more apt to than the comparison group to have been exposed to secondhand smoke not only in public places but at home, responsibility and private social functions, such as weddings, the researchers found.
Exposure to secondhand smoke appears to sincerely foster the risk for chronic sinusitis, a new Canadian swotting has found. In fact, it might explain 40 percent of the cases of the condition, said muse about author Dr C Martin Tammemagi, a researcher at Brock University in Ontario. "The numbers surprised me somewhat. My imprecise impression was that public health agencies were strongly discouraging smoking and controlling secondhand smoke, and that governments in similarity were passing protective legislation to adjust peoples' exposure to secondhand smoke".
But his team found that more than 90 percent of those in the study who had hardened sinusitis and more than 84 percent of the comparison group, which did not have the condition, were exposed to secondhand smoke in following places. "To see that exposure to secondhand smoke was still common did surprise and alarm me".
The depraved effects of secondhand smoke have been well-documented, and experts know it contains more than 4,000 substances, including 50 or more known or suspected carcinogens and many basic irritants, according to Tammemagi. The identify with between secondhand smoke and sinusitis, however, has been little studied. "To date, there have not been any high-quality studies that have looked at this carefully" and then estimated the lines that smoke plays in the sinus problem.
In their study, the researchers evaluated reports of secondhand smoke danger in 306 nonsmokers who had chronic rhinosinusitis, defined as swelling of the nose or sinuses lasting 12 weeks or longer. The sinuses are cavities within the cheek bones, around the eyes and behind the nose that moisten and dribble air within the nasal cavity.
The researchers asked the participants about their risk to secondhand smoke for the five years before their diagnosis and then compared the responses with those of 306 consumers of similar age, sex and race who did not have the sinus problem. Those with sinusitis were more apt to than the comparison group to have been exposed to secondhand smoke not only in public places but at home, responsibility and private social functions, such as weddings, the researchers found.
Saving Lives With Hemostatic Medicine
Saving Lives With Hemostatic Medicine.
A narcotize commonly employed to prevent excess bleeding in surgeries could keep thousands of people from bleeding to death after trauma, a unique study suggests. The drug, tranexamic acid (TXA) is cheap, greatly available around the world and easily administered. It works by significantly reducing the rate at which blood clots flout down, the researchers explained. "When people have serious injuries, whether from accidents or violence, and when they have fierce hemorrhage they can bleed to death.
This treatment reduces the chances of bleeding to death by about a sixth," said researcher Dr Ian Roberts, a professor of epidemiology at the London School of Hygiene and Tropical Medicine in the UK. According to Roberts, each year about 600000 society bleed to demise worldwide. "So, if you could bring down that by a sixth, you've saved 100000 lives in one year".
The report, which was on the whole funded by philanthropic groups and the British government, is published in the June 15 online issue of The Lancet. For the study, Roberts and colleagues in the CRASH-2 consortium randomly assigned more than 20000 trauma patients from 274 hospitals across 40 countries to injections of either TXA or placebo.
Among patients receiving TXA, the pace of expiry from any cause was cut by 10 percent compared to patients receiving placebo, the researchers found. In the TXA group, 14,5 percent of the patients died compared with 16 percent of the patients in the placebo group.
A narcotize commonly employed to prevent excess bleeding in surgeries could keep thousands of people from bleeding to death after trauma, a unique study suggests. The drug, tranexamic acid (TXA) is cheap, greatly available around the world and easily administered. It works by significantly reducing the rate at which blood clots flout down, the researchers explained. "When people have serious injuries, whether from accidents or violence, and when they have fierce hemorrhage they can bleed to death.
This treatment reduces the chances of bleeding to death by about a sixth," said researcher Dr Ian Roberts, a professor of epidemiology at the London School of Hygiene and Tropical Medicine in the UK. According to Roberts, each year about 600000 society bleed to demise worldwide. "So, if you could bring down that by a sixth, you've saved 100000 lives in one year".
The report, which was on the whole funded by philanthropic groups and the British government, is published in the June 15 online issue of The Lancet. For the study, Roberts and colleagues in the CRASH-2 consortium randomly assigned more than 20000 trauma patients from 274 hospitals across 40 countries to injections of either TXA or placebo.
Among patients receiving TXA, the pace of expiry from any cause was cut by 10 percent compared to patients receiving placebo, the researchers found. In the TXA group, 14,5 percent of the patients died compared with 16 percent of the patients in the placebo group.
Sports Prevents Breast Cancer
Sports Prevents Breast Cancer.
Vigorous make nervous on a regular basis might lend a hand protect black women against an aggressive form of breast cancer, researchers have found in Dec 2013. The unusual study included nearly 45000 black women, aged 30 and older, who were followed for nearly 20 years. Those who affianced in vigorous exercise for a lifetime average of three or more hours a week were 47 percent less in all probability to develop so-called estrogen receptor-negative breast cancer compared with those who exercised an common of one hour per week, the investigators found.
This type of bust cancer, which includes HER2-positive and triple-negative tumors, is linked to both higher incidence and death jeopardize in black women, compared to white women. These estrogen receptor-negative tumors do not return to the types of hormone therapies used to treat tumors that have the estrogen receptor, the researchers said in a Georgetown University Medical Center report release.
Vigorous make nervous on a regular basis might lend a hand protect black women against an aggressive form of breast cancer, researchers have found in Dec 2013. The unusual study included nearly 45000 black women, aged 30 and older, who were followed for nearly 20 years. Those who affianced in vigorous exercise for a lifetime average of three or more hours a week were 47 percent less in all probability to develop so-called estrogen receptor-negative breast cancer compared with those who exercised an common of one hour per week, the investigators found.
This type of bust cancer, which includes HER2-positive and triple-negative tumors, is linked to both higher incidence and death jeopardize in black women, compared to white women. These estrogen receptor-negative tumors do not return to the types of hormone therapies used to treat tumors that have the estrogen receptor, the researchers said in a Georgetown University Medical Center report release.
Very Few People Know How To Protect Yourself From Skin Cancer
Very Few People Know How To Protect Yourself From Skin Cancer.
A green subject survey by the American Academy of Dermatology finds that many subjects don't know enough about sun damage to protect themselves from developing skin cancer. "Our inspection showed that despite our repeated warnings about the dangers of UV exposure and the importance of proper Sunna protection, many people could not correctly answer true/false statements on the subject," said dermatologist Dr Zoe D Draelos, consulting professor at Duke University School of Medicine in Durham, NC, in a report release.
The assess found that only about one-third of more than 7000 people surveyed knew that neither ultraviolet A nor ultraviolet B rays are unharmed for your skin. "Quite simply, all forms of UV exposure, whether from not incongruous sunlight or artificial light sources found in tanning beds, are unsafe and are the No 1 preventable endanger factor for skin cancer".
A green subject survey by the American Academy of Dermatology finds that many subjects don't know enough about sun damage to protect themselves from developing skin cancer. "Our inspection showed that despite our repeated warnings about the dangers of UV exposure and the importance of proper Sunna protection, many people could not correctly answer true/false statements on the subject," said dermatologist Dr Zoe D Draelos, consulting professor at Duke University School of Medicine in Durham, NC, in a report release.
The assess found that only about one-third of more than 7000 people surveyed knew that neither ultraviolet A nor ultraviolet B rays are unharmed for your skin. "Quite simply, all forms of UV exposure, whether from not incongruous sunlight or artificial light sources found in tanning beds, are unsafe and are the No 1 preventable endanger factor for skin cancer".
Sunday, 22 December 2019
Living With HIV For People Over 50 Years
Living With HIV For People Over 50 Years.
One January broad daylight in 1991, business journalist Jane Fowler, then 55, opened a symbol from a health insurance company informing her that her request for coverage had been denied due to a "significant blood abnormality". This was the leading inkling - later confirmed in her doctor's office - that the Kansas City, Kan, first had contracted HIV from someone she had dated five years before, a male she'd been friends with her entire adult life. She had begun seeing him two years after the end of her 24-year marriage.
Fowler, now 75 and robust thanks to the advent of antiretroviral medications, recalls being devastated by her diagnosis. "I went deeply that day and literally took to my bed. I thought, 'What's successful to happen?'" she said. For the next four years Fowler, once an active and thriving writer and editor, lived in what she called "semi-isolation," staying mostly in her apartment. Then came the dawning perception that her isolation wasn't helping anyone, least of all herself.
Fowler slowly began reaching out to experts and other older Americans to acquire knowledge more about living with HIV in life's later decades. By 1995, she had helped co-found the National Association on HIV Over 50. And through her program, HIV Wisdom for Older Women, Fowler today speaks to audiences nationwide on the challenges of living with the virus. "I obvious to discourse out - to put an old, wrinkled, white, heterosexual pretence to this disease. But my import isn't age-specific: We all need to understand that we can be at risk".
That point may be more urgent than ever this Wednesday, World AIDS Day. During a recent White House forum on HIV and aging, at which Fowler spoke, experts presented unfamiliar data suggesting that as the HIV/AIDS rash enters its fourth decade those afflicted by it are aging, too.
One report, conducted by the AIDS Community Research Initiative of America (ACRIA), esteemed that 27 percent of Americans diagnosed with HIV are now age-old 50 or older and by 2015 that percentage could double. Why? According to Dr Michael Horberg, evil chair of the HIV Medicine Association, there's been a societal "perfect storm" that's led to more HIV infections amid people in middle age or older.
And "Certainly the happen of Viagra and similar drugs to treat erectile dysfunction, people are getting more sexually working because they are more able to do so". There's also the perception that HIV is now treatable with complex drug regimens even though these medicines often come with onerous string effects. For her part, Fowler said that more and more aging Americans think themselves recently divorced (as she did) or widowed and back in the dating game.
One January broad daylight in 1991, business journalist Jane Fowler, then 55, opened a symbol from a health insurance company informing her that her request for coverage had been denied due to a "significant blood abnormality". This was the leading inkling - later confirmed in her doctor's office - that the Kansas City, Kan, first had contracted HIV from someone she had dated five years before, a male she'd been friends with her entire adult life. She had begun seeing him two years after the end of her 24-year marriage.
Fowler, now 75 and robust thanks to the advent of antiretroviral medications, recalls being devastated by her diagnosis. "I went deeply that day and literally took to my bed. I thought, 'What's successful to happen?'" she said. For the next four years Fowler, once an active and thriving writer and editor, lived in what she called "semi-isolation," staying mostly in her apartment. Then came the dawning perception that her isolation wasn't helping anyone, least of all herself.
Fowler slowly began reaching out to experts and other older Americans to acquire knowledge more about living with HIV in life's later decades. By 1995, she had helped co-found the National Association on HIV Over 50. And through her program, HIV Wisdom for Older Women, Fowler today speaks to audiences nationwide on the challenges of living with the virus. "I obvious to discourse out - to put an old, wrinkled, white, heterosexual pretence to this disease. But my import isn't age-specific: We all need to understand that we can be at risk".
That point may be more urgent than ever this Wednesday, World AIDS Day. During a recent White House forum on HIV and aging, at which Fowler spoke, experts presented unfamiliar data suggesting that as the HIV/AIDS rash enters its fourth decade those afflicted by it are aging, too.
One report, conducted by the AIDS Community Research Initiative of America (ACRIA), esteemed that 27 percent of Americans diagnosed with HIV are now age-old 50 or older and by 2015 that percentage could double. Why? According to Dr Michael Horberg, evil chair of the HIV Medicine Association, there's been a societal "perfect storm" that's led to more HIV infections amid people in middle age or older.
And "Certainly the happen of Viagra and similar drugs to treat erectile dysfunction, people are getting more sexually working because they are more able to do so". There's also the perception that HIV is now treatable with complex drug regimens even though these medicines often come with onerous string effects. For her part, Fowler said that more and more aging Americans think themselves recently divorced (as she did) or widowed and back in the dating game.
Saturday, 21 December 2019
Many Survivors Of Lymphoma Did Not Receive A Recommendation To Take Further Tests For Other Types Of Cancer
Many Survivors Of Lymphoma Did Not Receive A Recommendation To Take Further Tests For Other Types Of Cancer.
Many Hodgkin lymphoma survivors don't notified of recommended bolstering screening tests for other cancers, a restored reflect on finds. "Most Hodgkin lymphoma patients are cured, but they can be at risk many years later of developing unessential cancers or other late effects of their initial treatment. This is why prominence of follow-up care post-treatment is so important," principal investigator Dr David Hodgson, a emanation oncologist at the Princess Margaret Hospital Cancer Program in Toronto, Canada, said in a University Health Network dispatch release.
He and his colleagues followed 2071 survivors for up to 15 years after Hodgkin lymphoma diagnosis and found that 62,5 percent were not screened for colorectal cancer, 32,3 percent were not screened for soul cancer, and 19,9 percent were not screened for cervical cancer. "Our results disclose that the optimal reinforcement care did not happen, even though most patients had visits with both a primary care provider and an oncologist in years two through five.
Many Hodgkin lymphoma survivors don't notified of recommended bolstering screening tests for other cancers, a restored reflect on finds. "Most Hodgkin lymphoma patients are cured, but they can be at risk many years later of developing unessential cancers or other late effects of their initial treatment. This is why prominence of follow-up care post-treatment is so important," principal investigator Dr David Hodgson, a emanation oncologist at the Princess Margaret Hospital Cancer Program in Toronto, Canada, said in a University Health Network dispatch release.
He and his colleagues followed 2071 survivors for up to 15 years after Hodgkin lymphoma diagnosis and found that 62,5 percent were not screened for colorectal cancer, 32,3 percent were not screened for soul cancer, and 19,9 percent were not screened for cervical cancer. "Our results disclose that the optimal reinforcement care did not happen, even though most patients had visits with both a primary care provider and an oncologist in years two through five.
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