Saving Lives With Hemostatic Medicine.
A narcotize commonly employed to prevent excess bleeding in surgeries could keep thousands of people from bleeding to death after trauma, a unique study suggests. The drug, tranexamic acid (TXA) is cheap, greatly available around the world and easily administered. It works by significantly reducing the rate at which blood clots flout down, the researchers explained. "When people have serious injuries, whether from accidents or violence, and when they have fierce hemorrhage they can bleed to death.
This treatment reduces the chances of bleeding to death by about a sixth," said researcher Dr Ian Roberts, a professor of epidemiology at the London School of Hygiene and Tropical Medicine in the UK. According to Roberts, each year about 600000 society bleed to demise worldwide. "So, if you could bring down that by a sixth, you've saved 100000 lives in one year".
The report, which was on the whole funded by philanthropic groups and the British government, is published in the June 15 online issue of The Lancet. For the study, Roberts and colleagues in the CRASH-2 consortium randomly assigned more than 20000 trauma patients from 274 hospitals across 40 countries to injections of either TXA or placebo.
Among patients receiving TXA, the pace of expiry from any cause was cut by 10 percent compared to patients receiving placebo, the researchers found. In the TXA group, 14,5 percent of the patients died compared with 16 percent of the patients in the placebo group.
Showing posts with label trauma. Show all posts
Showing posts with label trauma. Show all posts
Monday 23 December 2019
Wednesday 20 November 2019
Risk Factors For Alzheimer's Disease
Risk Factors For Alzheimer's Disease.
Older adults with homage problems and a narration of concussion have more buildup of Alzheimer's disease-associated plaques in the brain than those who also had concussions but don't have respect problems, according to a new study. "What we think it suggests is, head trauma is associated with Alzheimer's-type dementia - it's a endanger factor," said study researcher Michelle Mielke, an friend professor of epidemiology and neurology at Mayo Clinic Rochester. But it doesn't degenerate someone with head trauma is automatically going to develop Alzheimer's. Her turn over is published online Dec 26, 2013 and in the Jan 7, 2014 print version of the journal Neurology.
Previous studies looking at whether head trauma is a risk factor for Alzheimer's have come up with conflicting results. And Mielke stressed that she has found only a relate or association, not a cause-and-effect relationship. In the study, Mielke and her band evaluated 448 residents of Olmsted County, Minn, who had no signs of tribute problems.
They also evaluated another 141 residents with memory and thinking problems known as mild cognitive impairment. More than 5 million Americans have Alzheimer's disease, according to the Alzheimer's Association. Plaques are deposits of a protein scrap known as beta-amyloid that can erect up in between the brain's nerve cells. While most folk develop some with age, those who develop Alzheimer's generally get many more, according to the Alzheimer's Association.
They also minister to to get them in a predictable pattern, starting in brain areas crucial for memory. In the Mayo study, all participants were venerable 70 or older. The participants reported if they ever had a brain injury that implicated loss of consciousness or memory. Of the 448 without any memory problems, 17 percent had reported a cognition injury. Of the 141 with memory problems, 18 percent did.
Older adults with homage problems and a narration of concussion have more buildup of Alzheimer's disease-associated plaques in the brain than those who also had concussions but don't have respect problems, according to a new study. "What we think it suggests is, head trauma is associated with Alzheimer's-type dementia - it's a endanger factor," said study researcher Michelle Mielke, an friend professor of epidemiology and neurology at Mayo Clinic Rochester. But it doesn't degenerate someone with head trauma is automatically going to develop Alzheimer's. Her turn over is published online Dec 26, 2013 and in the Jan 7, 2014 print version of the journal Neurology.
Previous studies looking at whether head trauma is a risk factor for Alzheimer's have come up with conflicting results. And Mielke stressed that she has found only a relate or association, not a cause-and-effect relationship. In the study, Mielke and her band evaluated 448 residents of Olmsted County, Minn, who had no signs of tribute problems.
They also evaluated another 141 residents with memory and thinking problems known as mild cognitive impairment. More than 5 million Americans have Alzheimer's disease, according to the Alzheimer's Association. Plaques are deposits of a protein scrap known as beta-amyloid that can erect up in between the brain's nerve cells. While most folk develop some with age, those who develop Alzheimer's generally get many more, according to the Alzheimer's Association.
They also minister to to get them in a predictable pattern, starting in brain areas crucial for memory. In the Mayo study, all participants were venerable 70 or older. The participants reported if they ever had a brain injury that implicated loss of consciousness or memory. Of the 448 without any memory problems, 17 percent had reported a cognition injury. Of the 141 with memory problems, 18 percent did.
Tuesday 16 January 2018
The Number Of Head Injuries Among Child Has Increased Significantly Since 2007
The Number Of Head Injuries Among Child Has Increased Significantly Since 2007.
The legions of depreciatory head traumas among infants and teenage children appears to have risen dramatically across the United States since the onset of the in touch recession in 2007, new research reveals. The observation linking poor economics to an dilate in one of the most extreme forms of child abuse stems from a focused analysis on shifting caseload numbers in four urban children's hospitals.
But the declaration may ultimately touch upon a broader public trend. "Abusive head trauma - previously known as 'shaken baby syndrome' - is the cardinal cause of death from child abuse, if you don't count neglect," noted over author Dr Rachel P Berger, an assistant professor of pediatrics at the University of Pittsburgh School of Medicine. "And so, what's apropos here is that we saw in four cities that there was a unmistakable increase in the rate of abusive head trauma among children during the recession compared with beforehand".
So "Now we be informed that poverty and stress are clearly related to child abuse. And during times of solvent hardship one of the things that's hardest hit are the social services that are most needed to prevent offspring abuse. So, this is really worrisome".
Berger, who also serves as an attending physician at the Children's Hospital of Pittsburgh, is slated to now her findings with her colleagues Saturday at the Pediatric Academic Societies' annual conclave in Vancouver, British Columbia, Canada. To gain insight into how the ebb and flow of thersitical head trauma cases might correlate with economic ups and downs, the research team looked over the 2004-2009 records of four urban children's hospitals.
The hospitals were located in Pittsburgh, Seattle, Cincinnati and Columbus, Ohio. Only cases of "unequivocal" injurious chair trauma were included in the data. The slump was deemed to have begun on Dec 1, 2007, and continued through the end of the sanctum period on Dec 31, 2009.
Throughout the study period, Berger and her team recorded 511 cases of trauma. The common age of these cases was a little over 9 months, although patients ranged from as babyish as 9 days old to 6.5 years old. Nearly six in 10 patients were male, and about the same cut were white. Overall, 16 percent of the children died from their injuries.
The legions of depreciatory head traumas among infants and teenage children appears to have risen dramatically across the United States since the onset of the in touch recession in 2007, new research reveals. The observation linking poor economics to an dilate in one of the most extreme forms of child abuse stems from a focused analysis on shifting caseload numbers in four urban children's hospitals.
But the declaration may ultimately touch upon a broader public trend. "Abusive head trauma - previously known as 'shaken baby syndrome' - is the cardinal cause of death from child abuse, if you don't count neglect," noted over author Dr Rachel P Berger, an assistant professor of pediatrics at the University of Pittsburgh School of Medicine. "And so, what's apropos here is that we saw in four cities that there was a unmistakable increase in the rate of abusive head trauma among children during the recession compared with beforehand".
So "Now we be informed that poverty and stress are clearly related to child abuse. And during times of solvent hardship one of the things that's hardest hit are the social services that are most needed to prevent offspring abuse. So, this is really worrisome".
Berger, who also serves as an attending physician at the Children's Hospital of Pittsburgh, is slated to now her findings with her colleagues Saturday at the Pediatric Academic Societies' annual conclave in Vancouver, British Columbia, Canada. To gain insight into how the ebb and flow of thersitical head trauma cases might correlate with economic ups and downs, the research team looked over the 2004-2009 records of four urban children's hospitals.
The hospitals were located in Pittsburgh, Seattle, Cincinnati and Columbus, Ohio. Only cases of "unequivocal" injurious chair trauma were included in the data. The slump was deemed to have begun on Dec 1, 2007, and continued through the end of the sanctum period on Dec 31, 2009.
Throughout the study period, Berger and her team recorded 511 cases of trauma. The common age of these cases was a little over 9 months, although patients ranged from as babyish as 9 days old to 6.5 years old. Nearly six in 10 patients were male, and about the same cut were white. Overall, 16 percent of the children died from their injuries.
Thursday 10 March 2016
In Illinois, Transportation Of Patients Did Not Fit Into The Designated Period Of Time
In Illinois, Transportation Of Patients Did Not Fit Into The Designated Period Of Time.
Most trauma patients transferred between facilities in the affirm of Illinois don't convert it to their irrefutable destination within the two hours mandated by the state. But the most strictly injured patients did make it within the time window, suggesting that physicians are fittingly triaging patients, according to a study in the December issue of the Archives of Surgery. "If you didn't get there within two hours, it definitely didn't make any difference in markers of severity," said study co-author Dr Thomas J Esposito, foremost of the division of trauma, surgical critical guardianship and burns in the department of surgery at Loyola University Chicago Stritch School of Medicine in Maywood, Ill. "If radical to their own devices, doctors may not need onerous advice on what to do".
And "The directive is iffy and - probably doesn't matter in that the sickest people are being recognized and transferred more quickly," added Dr Mark Gestring, medical governor of the Strong Regional Trauma Center at the University of Rochester Medical Center. "The organize is driven by how odd the patients are, and the truly sick patients are making the trip in enough time".
In fact, Esposito stated, there may be a downside to having such a rule. "It sets up a kettle of fish in that someone can say you were assumed to get my loved one or my client here in two hours and that didn't happen - I'm looking for some compensation because you were out of compliance". And it may even bowl over trauma centers with patients that don't really need to be there.
When patients are injured, they may not be near a clinic or trauma center that can help them, so are treated initially either at a local hospital, by pinch medical technicians or both. "That first hospital can't finish the job, then the lenient needs to move on after life-threatening conditions are dealt with". After patients are stabilized, they can be moved to another masterliness which has, for example, a neurosurgeon to deal with that particular injury.
Most trauma patients transferred between facilities in the affirm of Illinois don't convert it to their irrefutable destination within the two hours mandated by the state. But the most strictly injured patients did make it within the time window, suggesting that physicians are fittingly triaging patients, according to a study in the December issue of the Archives of Surgery. "If you didn't get there within two hours, it definitely didn't make any difference in markers of severity," said study co-author Dr Thomas J Esposito, foremost of the division of trauma, surgical critical guardianship and burns in the department of surgery at Loyola University Chicago Stritch School of Medicine in Maywood, Ill. "If radical to their own devices, doctors may not need onerous advice on what to do".
And "The directive is iffy and - probably doesn't matter in that the sickest people are being recognized and transferred more quickly," added Dr Mark Gestring, medical governor of the Strong Regional Trauma Center at the University of Rochester Medical Center. "The organize is driven by how odd the patients are, and the truly sick patients are making the trip in enough time".
In fact, Esposito stated, there may be a downside to having such a rule. "It sets up a kettle of fish in that someone can say you were assumed to get my loved one or my client here in two hours and that didn't happen - I'm looking for some compensation because you were out of compliance". And it may even bowl over trauma centers with patients that don't really need to be there.
When patients are injured, they may not be near a clinic or trauma center that can help them, so are treated initially either at a local hospital, by pinch medical technicians or both. "That first hospital can't finish the job, then the lenient needs to move on after life-threatening conditions are dealt with". After patients are stabilized, they can be moved to another masterliness which has, for example, a neurosurgeon to deal with that particular injury.
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