In The USA Scientists Have Found The New Causes Of Glaucoma.
Glucosamine supplements that millions of Americans select to balm treat up on and knee osteoarthritis may have an unexpected side effect: They may increase risk for developing glaucoma, a scanty new study of older adults suggests in May 2013. Glaucoma occurs when there is an proliferation of intraocular pressure (IOP) or pressure inside the eye. Left untreated, glaucoma is one of the unsurpassed causes of blindness.
In the new study of 17 people, whose average age was 76 years, 11 participants had their optic pressure measured before, during and after taking glucosamine supplements. The other six had their liking pressure measured while and after they took the supplements. Overall, pressure inside the sidelong glance was higher when participants were taking glucosamine, but did return to normal after they stopped taking these supplements, the study showed.
So "This swatting shows a reversible effect of these changes, which is reassuring," wrote researchers led by Dr Ryan Murphy at the University of New England College of Osteopathic Medicine in Biddeford, Maine. "However, the likelihood that constant damage can result from prolonged use of glucosamine supplementation is not eliminated. Monitoring IOP in patients choosing to extend with glucosamine may be indicated".
Exactly how glucosamine supplements could affect power inside the eye is not fully understood, but several theories exist. For example, glucosamine is a harbinger for molecules called glycosaminoglycans, which may elevate eye pressure. The findings are published online May 23 as a delving letter in JAMA Ophthalmology.
Tuesday, 7 January 2020
Testing A New Experimental Drug To Raise Good Cholesterol Level
Testing A New Experimental Drug To Raise Good Cholesterol Level.
An conjectural poison that raises HDL, or "good," cholesterol seems to have passed an sign hurdle by proving safe in preliminary trials. Although the trial was primarily designed to overlook at safety, researchers scheduled to present the finding Wednesday at the American Heart Association's annual assignation in Chicago also report that anacetrapib raised HDL cholesterol by 138 percent and slap in the face LDL, HDL's evil twin, almost in half. "We saw very encouraging reductions in clinical events," said Dr Christopher Cannon, assume command author of the study, which also appears in the Nov 18, 2010 exit of the New England Journal of Medicine.
A big study to seal the results would take four to five years to complete so the drug is still years away from market who is a cardiologist with Brigham and Women's Hospital in Boston. Other experts are intrigued by the findings, but note that the check out is still in very ahead stages. "There are a lot of people in the prevention/lipid field that are simultaneously excited and leery," said Dr Howard Weintraub, clinical concert-master of the Center for the Prevention of Cardiovascular Disease at NYU Langone Medical Center in New York City.
Added Dr John C LaRosa, president of the State University of New York (SUNY) Downstate Medical Center in New York City: "It's very prodromic but it's material because the final drug out of the barrel of this type was not a success. This looks match a better drug, but it's not definitive by any means. Don't take this to the bank".
LaRosa was referring to torcetrapib, which, get off on anacetrapib, belongs to the class of drugs known as cholesterol ester take protein (CETP) inhibitors. A large trial on torcetrapib was killed after investigators found an increased jeopardy of death and other cardiovascular outcomes. "I would be more excited about anacetrapib if I hadn't seen what happened to its cousin torcetrapib. Torcetrapib raised HDL astoundingly but that was completely neutralized by the development in cardiovascular events".
An conjectural poison that raises HDL, or "good," cholesterol seems to have passed an sign hurdle by proving safe in preliminary trials. Although the trial was primarily designed to overlook at safety, researchers scheduled to present the finding Wednesday at the American Heart Association's annual assignation in Chicago also report that anacetrapib raised HDL cholesterol by 138 percent and slap in the face LDL, HDL's evil twin, almost in half. "We saw very encouraging reductions in clinical events," said Dr Christopher Cannon, assume command author of the study, which also appears in the Nov 18, 2010 exit of the New England Journal of Medicine.
A big study to seal the results would take four to five years to complete so the drug is still years away from market who is a cardiologist with Brigham and Women's Hospital in Boston. Other experts are intrigued by the findings, but note that the check out is still in very ahead stages. "There are a lot of people in the prevention/lipid field that are simultaneously excited and leery," said Dr Howard Weintraub, clinical concert-master of the Center for the Prevention of Cardiovascular Disease at NYU Langone Medical Center in New York City.
Added Dr John C LaRosa, president of the State University of New York (SUNY) Downstate Medical Center in New York City: "It's very prodromic but it's material because the final drug out of the barrel of this type was not a success. This looks match a better drug, but it's not definitive by any means. Don't take this to the bank".
LaRosa was referring to torcetrapib, which, get off on anacetrapib, belongs to the class of drugs known as cholesterol ester take protein (CETP) inhibitors. A large trial on torcetrapib was killed after investigators found an increased jeopardy of death and other cardiovascular outcomes. "I would be more excited about anacetrapib if I hadn't seen what happened to its cousin torcetrapib. Torcetrapib raised HDL astoundingly but that was completely neutralized by the development in cardiovascular events".
Skiing Prolongs Life
Skiing Prolongs Life.
Hitting the slopes soon? A unexplored writing-room suggests that's a good idea, because skiing and snowboarding holidays can boost your overall happiness. Researchers surveyed 279 visitors at three principal ski resorts in South Korea. Of those people, 126 were skiers, 112 were snowboarders and 41 did both. Participants worn out an mean of 4,5 days at a resort, and 90 percent visited ski resorts less than five times a season.
Hitting the slopes soon? A unexplored writing-room suggests that's a good idea, because skiing and snowboarding holidays can boost your overall happiness. Researchers surveyed 279 visitors at three principal ski resorts in South Korea. Of those people, 126 were skiers, 112 were snowboarders and 41 did both. Participants worn out an mean of 4,5 days at a resort, and 90 percent visited ski resorts less than five times a season.
People Often Die In Their Sleep
People Often Die In Their Sleep.
People with doze apnea and hard-to-control drunk blood pressure may see their blood pressure drop if they treat the catnap disorder, Spanish researchers report. Continuous positive airway pressure (CPAP) is the orthodox treatment for sleep apnea, a condition characterized by disrupted breathing during sleep. The drop disorder has been linked to high blood pressure. Patients in this study were taking three or more drugs to tone down their blood pressure, in addition to having sleep apnea.
Participants who used the CPAP device for 12 weeks reduced their diastolic blood compel (the bottom number in a blood pressure reading) and improved their overall nighttime blood pressure, the researchers found. "The popularity of sleep apnea in patients with uncompliant high blood pressure is very high," said lead researcher Dr Miguel-Angel Martinez-Garcia, from the Polytechnic University Hospital in Valencia. "This forty winks apnea therapy increases the probability of recovering the normal nocturnal blood pressure pattern.
Patients with resistant great in extent blood pressure should undergo a sleep study to rule out obstructive sleep apnea, Martinez-Garcia said. "If the resolute has sleep apnea, he should be treated with CPAP and undergo blood compression monitoring". The report, published in the Dec 11, 2013 issue of the Journal of the American Medical Association, was partly funded by Philips-Respironics, maker of the CPAP combination used in the study.
The CPAP organized whole consists of a motor that pushes air through a tube connected to a mask that fits over the patient's announce and nose. The device keeps the airway from closing, and thus allows interminable sleep. Sleep apnea is a common disorder. The pauses in breathing that patients know-how can last from a few seconds to minutes and they can occur 30 times or more an hour.
People with doze apnea and hard-to-control drunk blood pressure may see their blood pressure drop if they treat the catnap disorder, Spanish researchers report. Continuous positive airway pressure (CPAP) is the orthodox treatment for sleep apnea, a condition characterized by disrupted breathing during sleep. The drop disorder has been linked to high blood pressure. Patients in this study were taking three or more drugs to tone down their blood pressure, in addition to having sleep apnea.
Participants who used the CPAP device for 12 weeks reduced their diastolic blood compel (the bottom number in a blood pressure reading) and improved their overall nighttime blood pressure, the researchers found. "The popularity of sleep apnea in patients with uncompliant high blood pressure is very high," said lead researcher Dr Miguel-Angel Martinez-Garcia, from the Polytechnic University Hospital in Valencia. "This forty winks apnea therapy increases the probability of recovering the normal nocturnal blood pressure pattern.
Patients with resistant great in extent blood pressure should undergo a sleep study to rule out obstructive sleep apnea, Martinez-Garcia said. "If the resolute has sleep apnea, he should be treated with CPAP and undergo blood compression monitoring". The report, published in the Dec 11, 2013 issue of the Journal of the American Medical Association, was partly funded by Philips-Respironics, maker of the CPAP combination used in the study.
The CPAP organized whole consists of a motor that pushes air through a tube connected to a mask that fits over the patient's announce and nose. The device keeps the airway from closing, and thus allows interminable sleep. Sleep apnea is a common disorder. The pauses in breathing that patients know-how can last from a few seconds to minutes and they can occur 30 times or more an hour.
A Tan Is Still Admired By Ignoring The Danger Of Cancer
A Tan Is Still Admired By Ignoring The Danger Of Cancer.
Despite significant concerns about pellicle cancer, a the better of Americans nevertheless regard that having a tan is an attractive, desirable and healthy look, a new national survey finds. The enumerate was conducted by the American Academy of Dermatology (AAD) in January, and included just over 7100 men and women nationwide. "Our enquiry highlighted the contradictory feelings that many people have about tanning - they love the way a tan looks but are concerned about skin cancer, which is estimated to choose about one in five Americans in their lifetime," Dr Zoe D Draelos, a dermatologist and consulting professor at Duke University School of Medicine in Durham NC, said in a telecast release.
So "What they may not net is that no matter whether you tan or burn, a tan from the sun or tanning beds damages the peel and can cause wrinkles, age spots and skin cancer. The challenge is changing the long-standing attitudes about tanning to correlate with people's proficiency about skin cancer".
Despite significant concerns about pellicle cancer, a the better of Americans nevertheless regard that having a tan is an attractive, desirable and healthy look, a new national survey finds. The enumerate was conducted by the American Academy of Dermatology (AAD) in January, and included just over 7100 men and women nationwide. "Our enquiry highlighted the contradictory feelings that many people have about tanning - they love the way a tan looks but are concerned about skin cancer, which is estimated to choose about one in five Americans in their lifetime," Dr Zoe D Draelos, a dermatologist and consulting professor at Duke University School of Medicine in Durham NC, said in a telecast release.
So "What they may not net is that no matter whether you tan or burn, a tan from the sun or tanning beds damages the peel and can cause wrinkles, age spots and skin cancer. The challenge is changing the long-standing attitudes about tanning to correlate with people's proficiency about skin cancer".
Monday, 6 January 2020
Depression Plus Diabetes Kills Women
Depression Plus Diabetes Kills Women.
Women pain from both diabetes and unhappiness have a greater risk of dying, especially from heart disease, a new study suggests. In fact, women with both conditions have a twofold increased peril of death, researchers say. "People with both conditions are at very hilarious risk of death," said lead researcher Dr Frank B Hu, a professor of nostrum at Harvard Medical School. "Those are double whammies". When males and females are afflicted by both diseases, these conditions can lead to a "vicious cycle. People with diabetes are more likely to be depressed, because they are under long-term psychosocial stress, which is associated with diabetes complications".
People with diabetes who are depressed are less no doubt to abduct care of themselves and effectively manage their diabetes. "That can lead to complications, which increase the risk of mortality". Hu stressed that it is signal to manage both the diabetes and the depression to lower the mortality risk. "It is reachable that these two conditions not only influence each other biologically, but also behaviorally".
Type 2 diabetes and depression are often allied to unhealthy lifestyles, including smoking, poor diet and lack of exercise, according to the researchers. In addition, gloominess may trigger changes in the nervous system that adversely affect the heart. The promulgate is published in the January, 2011 issue of the Archives of General Psychiatry.
Commenting on the study, Dr Luigi Meneghini, an collaborator professor of clinical medicine and director of the Eleanor and Joseph Kosow Diabetes Treatment Center at the Diabetes Research Institute of the University of Miami Miller School of Medicine, said the findings were not surprising. "The review highlights that there is a lustrous increase in jeopardize to your health and to your life when you have a combination of diabetes and depression".
Women pain from both diabetes and unhappiness have a greater risk of dying, especially from heart disease, a new study suggests. In fact, women with both conditions have a twofold increased peril of death, researchers say. "People with both conditions are at very hilarious risk of death," said lead researcher Dr Frank B Hu, a professor of nostrum at Harvard Medical School. "Those are double whammies". When males and females are afflicted by both diseases, these conditions can lead to a "vicious cycle. People with diabetes are more likely to be depressed, because they are under long-term psychosocial stress, which is associated with diabetes complications".
People with diabetes who are depressed are less no doubt to abduct care of themselves and effectively manage their diabetes. "That can lead to complications, which increase the risk of mortality". Hu stressed that it is signal to manage both the diabetes and the depression to lower the mortality risk. "It is reachable that these two conditions not only influence each other biologically, but also behaviorally".
Type 2 diabetes and depression are often allied to unhealthy lifestyles, including smoking, poor diet and lack of exercise, according to the researchers. In addition, gloominess may trigger changes in the nervous system that adversely affect the heart. The promulgate is published in the January, 2011 issue of the Archives of General Psychiatry.
Commenting on the study, Dr Luigi Meneghini, an collaborator professor of clinical medicine and director of the Eleanor and Joseph Kosow Diabetes Treatment Center at the Diabetes Research Institute of the University of Miami Miller School of Medicine, said the findings were not surprising. "The review highlights that there is a lustrous increase in jeopardize to your health and to your life when you have a combination of diabetes and depression".
Americans Rarely Write Wills
Americans Rarely Write Wills.
Most Americans do not deal with end-of-life issues and wishes, a original lessons indicates. Researchers analyzed data from nearly 8000 people who took break up in nationwide surveys conducted in 2009 and 2010, and found that only about 26 percent had completed an advance directive, also called a living will. There were significant associations between completing an go forward directive and age, income, knowledge and health status, according to the study in the January issue of the American Journal of Preventive Medicine.
Advance directives were more hackneyed among women, whites, married people and those who had a college degree or postgraduate training. People with advanced directives also were more inclined to to have a chronic disease or a regular source of care. "For raven and Hispanic respondents, advance directives were less frequent across all educational groups.
Most Americans do not deal with end-of-life issues and wishes, a original lessons indicates. Researchers analyzed data from nearly 8000 people who took break up in nationwide surveys conducted in 2009 and 2010, and found that only about 26 percent had completed an advance directive, also called a living will. There were significant associations between completing an go forward directive and age, income, knowledge and health status, according to the study in the January issue of the American Journal of Preventive Medicine.
Advance directives were more hackneyed among women, whites, married people and those who had a college degree or postgraduate training. People with advanced directives also were more inclined to to have a chronic disease or a regular source of care. "For raven and Hispanic respondents, advance directives were less frequent across all educational groups.
New Way To Treat Parkinson's Disease
New Way To Treat Parkinson's Disease.
Deep thought stimulation might staff improve the driving ability of people with Parkinson's disease, a new German ponder suggests. A deep brain stimulator is an implanted device that sends electrical impulses to the brain. With patients who have epilepsy, the stimulator is believed to farther down the risk of seizures, the researchers said. A driving simulator tested the abilities of 23 Parkinson's patients with a acute wit stimulator, 21 patients without the device and a control group of 21 people without Parkinson's.
Deep thought stimulation might staff improve the driving ability of people with Parkinson's disease, a new German ponder suggests. A deep brain stimulator is an implanted device that sends electrical impulses to the brain. With patients who have epilepsy, the stimulator is believed to farther down the risk of seizures, the researchers said. A driving simulator tested the abilities of 23 Parkinson's patients with a acute wit stimulator, 21 patients without the device and a control group of 21 people without Parkinson's.
Physicians In The USA Recommend To Make A Mammography To All Women
Physicians In The USA Recommend To Make A Mammography To All Women.
More than three years after disputable recent guidelines rejected bit annual mammograms for most women, women in all age groups continue to get yearly screenings, a unusual survey shows. In fact, mammogram rates actually increased overall, from 51,9 percent in 2008 to 53,6 percent in 2011, even though the lightly made rise was not considered statistically significant, according to the researchers from Brigham and Women's Hospital and Harvard Medical School. "There have been no significant changes in the proportion of screening mammograms surrounded by any age group, but in particular among women under ripen 50," said the study leader, Dr Lydia Pace, a global women's fettle fellow in the division of women's health at Brigham and Women's.
While the study did not look at the reasons for continued screening, the researchers speculated that conflicting recommendations from various maestro organizations may play a role. In 2009, the US Preventive Services Task Force, an maverick panel of experts, issued unknown guidelines that said women younger than 50 don't need routine annual mammograms and those 50 to 74 could get screened every two years. Before that, the commendation was that all women elderly 40 and older get mammograms every one to two years.
The recommendations ignited much controversy and renewed dispute about whether delayed screening would increase breast cancer mortality. Since then, organizations such as the American Cancer Society have adhered to the recommendations that women 40 and older be screened annually. To undergo what object the new task force recommendations have had, the researchers analyzed facts from almost 28000 women over a six-year period - before and after the new task force guidelines.
The women were responding to the National Health Interview Survey in 2005, 2008 and 2011, and were asked how often they got a mammogram for screening purposes. Across the ages, there was no decay in screenings, the researchers found. Among women 40 to 49, the rates rose slightly, from 46,1 percent in 2008 to 47,5 percent in 2011. Among women old 50 to 74, the rates also rose, from 57,2 percent in 2008 to 59,1 percent in 2011.
More than three years after disputable recent guidelines rejected bit annual mammograms for most women, women in all age groups continue to get yearly screenings, a unusual survey shows. In fact, mammogram rates actually increased overall, from 51,9 percent in 2008 to 53,6 percent in 2011, even though the lightly made rise was not considered statistically significant, according to the researchers from Brigham and Women's Hospital and Harvard Medical School. "There have been no significant changes in the proportion of screening mammograms surrounded by any age group, but in particular among women under ripen 50," said the study leader, Dr Lydia Pace, a global women's fettle fellow in the division of women's health at Brigham and Women's.
While the study did not look at the reasons for continued screening, the researchers speculated that conflicting recommendations from various maestro organizations may play a role. In 2009, the US Preventive Services Task Force, an maverick panel of experts, issued unknown guidelines that said women younger than 50 don't need routine annual mammograms and those 50 to 74 could get screened every two years. Before that, the commendation was that all women elderly 40 and older get mammograms every one to two years.
The recommendations ignited much controversy and renewed dispute about whether delayed screening would increase breast cancer mortality. Since then, organizations such as the American Cancer Society have adhered to the recommendations that women 40 and older be screened annually. To undergo what object the new task force recommendations have had, the researchers analyzed facts from almost 28000 women over a six-year period - before and after the new task force guidelines.
The women were responding to the National Health Interview Survey in 2005, 2008 and 2011, and were asked how often they got a mammogram for screening purposes. Across the ages, there was no decay in screenings, the researchers found. Among women 40 to 49, the rates rose slightly, from 46,1 percent in 2008 to 47,5 percent in 2011. Among women old 50 to 74, the rates also rose, from 57,2 percent in 2008 to 59,1 percent in 2011.
Military Suffer From Depression
Military Suffer From Depression.
Private contractors who worked in Afghanistan, Iraq and other brawl zones over the since two years have high rates of depression and post-traumatic burden disorder (PTSD), a new study finds. Researchers conducted an anonymous online appraisal of 660 contractors who had been deployed to a conflict zone at least once between early 2011 and early 2013, and found that 25 percent met the criteria for PTSD and 18 percent for depression. Half reported liquor misuse.
Despite these problems, few contractors received serve before or after deployment, according to the study by the RAND Corp, a nonprofit explore organization. Even though most of them had health insurance, only 28 percent of those with PTSD and 34 percent of those with hollow reported receiving mental health treatment in the previous 12 months. Many contractors also reported material health problems as a result of deployment, including traumatic intellect injuries, respiratory issues, back pain and hearing problems, the study authors pointed out in a RAND announcement release.
Private contractors who worked in Afghanistan, Iraq and other brawl zones over the since two years have high rates of depression and post-traumatic burden disorder (PTSD), a new study finds. Researchers conducted an anonymous online appraisal of 660 contractors who had been deployed to a conflict zone at least once between early 2011 and early 2013, and found that 25 percent met the criteria for PTSD and 18 percent for depression. Half reported liquor misuse.
Despite these problems, few contractors received serve before or after deployment, according to the study by the RAND Corp, a nonprofit explore organization. Even though most of them had health insurance, only 28 percent of those with PTSD and 34 percent of those with hollow reported receiving mental health treatment in the previous 12 months. Many contractors also reported material health problems as a result of deployment, including traumatic intellect injuries, respiratory issues, back pain and hearing problems, the study authors pointed out in a RAND announcement release.
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