Scanning The Human Genome Provide Insights Into The Likelihood Of Future Disease

Scanning The Human Genome Provide Insights Into The Likelihood Of Future Disease.
Stephen Quake, a Stanford University professor of bioengineering, now has a very virtuous atmosphere of his own genetic destiny. Quake's DNA was the focal point of the first completely mapped genome of a tonic person aimed at predicting future health risks. The scrutinize was conducted by a team of Stanford researchers and cost about $50,000. The researchers say they can now augur Quake's risk for dozens of diseases and how he might respond to a number of widely used medicines.

This breed of individualized risk report could become common within the next decade and may become much cheaper, according to the Stanford team. "The $1000 genome evaluation is coming fast. The challenge lies in knowing what to do with all that information. We've focused on establishing priorities that will be most kind when a patient and a physician are sitting together looking at the computer screen," Euan Ashley, an helpmate professor of medicine, said in a university news release.

Those priorities count assessing how a person's activity levels, weight, diet and other lifestyle habits pool with his or her genetic risk for, or protection against, health problems such as diabetes or ticker attack. It's also important to determine if a certain medication is likely to benefit the patient or cause detrimental side effects.

"We're at the dawn of a new age in genomics. Information like this will enable doctors to transfer personalized health care like never before. Patients at risk for certain diseases will be able to welcome closer monitoring and more frequent testing, while those who are at lower risk will be spared unnecessary tests. This will have consequential economic benefits as well, because it improves the efficiency of medicine".

In mapping Quake's genome, researchers designed an algorithm that overlaid his genetic data, on vertex of what was already known about his fitness risks based on his age and gender. The analysis focused on 55 conditions, ranging from diabetes and tubbiness to gum disease and schizophrenia.

The analysis revealed that Quake has a 23 percent gamble of prostate cancer and a 1,4 percent risk of Alzheimer's disease. He also has a more than 50 percent befall of developing obesity, type 2 diabetes and coronary artery disease. However, lifestyle habits can have a stinking impact on genetic risk factors, the experts noted.

Speaking to the Associated Press, Quake said that a special genome reading might not be a great idea for everyone. "All you listen about when they talk about your genome is ways you're going to die and get sick. It doesn't delineate you you're going to be happy or a great athlete. If you're a worrier, this is not for you".

And another crack unconnected to the research worried about privacy issues. "The genie is now out of the bottle," Nilesh Samani, of the section of cardiovascular sciences at the University of Leicester, told the AP. "We need to cogitate carefully about whether we need laws to prevent genetic information from getting into the wrong hands".

The research was funded by the US National Institute of General Medical Sciences, and the National Heart, Lung and Blood Institute, in the midst others. All the researchers have either pecuniary ties to, or are involved with, genetic testing firms, medicament makers or other health industry companies click this link. The inspection was released online April 29 and will be published in the May 1 print issue of The Lancet.