Showing posts with label colon. Show all posts
Showing posts with label colon. Show all posts

Thursday, 2 January 2020

Preparation For Colonoscopy As A Tablet Relieves Suffering From The Procedure

Preparation For Colonoscopy As A Tablet Relieves Suffering From The Procedure.
One saneness many colonize dread a colonoscopy is the unpleasant preparation, which often requires that they liquid refreshment a gallon of prescribed fluids to clear out their bowels before the procedure. But an industry-funded haunt suggests that a pill could negate the need for so much liquid. Researchers from Henry Ford Hospital story that people preparing for the test were able to take a pill approved as a treatment for chronic constipation and keep off half of the liquid requirement.

In the study, 126 people took either the pill - lubiprostone (Amitiza) - or an sluggish placebo. Those who took the combination of the pill and liquid were better able to suffer the preparation than were those who drank a gallon of a mixture of polyethylene glycol and electrolytes, the study found. "Most bourgeoisie say they don't want to have a colonoscopy because they find the preparation intolerable," the study's lead author, Dr Chetan Pai, a gastroenterologist, said in a telecast release from the hospital.

So "If physicians are able to present oneself a better way to prep, I think this will encourage more people to get the colonoscopies that may save their lives". Pai also spiked out that about 90 percent of colon cancer cases occur in people older than 50, an majority group that tends to have an especially hard time drinking the gallon of liquid often prescribed for colonoscopy preparation. The study, scheduled to be presented Sunday at the Digestive Diseases Week seminar in New Orleans, was funded by the pill's industrialist Sucampo Pharmaceuticals.

A colonoscopy is an internal exam of the colon (large intestine) and rectum, using an instrument called a colonoscope. How the Test is Performed. The colonoscope has a minute camera attached to a flexible tube. Unlike sigmoidoscopy, which can only stir the lower third of the colon, colonoscopy examines the entire length of the colon.

Wednesday, 1 January 2020

Hispanic Men Are More Likely To Suffer From Polyps in Colon Than Women

Hispanic Men Are More Likely To Suffer From Polyps in Colon Than Women.
Among Hispanics, men are twice as right as women to have colon polyps and are also more appropriate to have multiple polyps, a restored study in Puerto Rico has found. The researchers also found that the scan patients older than 60 were 56 percent more likely to have polyps than those younger than 60. Polyps are growths in the stocky intestine. Some polyps may already be cancerous or can become cancerous.

The exploration included 647 patients aged 50 and older undergoing colorectal cancer screening at a gastroenterology clinic in Puerto Rico. In 70 percent of patients with polyps, the growths were on the dexter sect of the colon. In white patients, polyps are typically found on the left incidental of the colon. This difference may result from underlying molecular differences in the two patient groups, said examination author Dr Marcia Cruz-Correa, an associate professor of medicine and biochemistry at the University of Puerto Rico Cancer Center.

The decree about polyp location is important because it highlights the call to use colonoscopy when conducting colorectal cancer screening in Hispanics. This is the most effective pattern of detecting polyps on the right side of the colon. The study was to be presented Sunday at the Digestive Diseases Week meet in New Orleans.

Friday, 6 December 2019

The Use Of Colonoscopy Reduces The Risk Of Colon Cancer

The Use Of Colonoscopy Reduces The Risk Of Colon Cancer.
In annexe to reducing the danger of cancer on the left side of the colon, strange research indicates that colonoscopies may also reduce cancer risk on the right side. The judgement contradicts some previous research that had indicated a right-side "blind spots" when conducting colonoscopies. However, the right-side better shown in the new study, published in the Jan 4, 2011 issue of the Annals of Internal Medicine, was somewhat less effective than that seen on the left side.

And "We didn't really have able-bodied data proving that anything is very good at preventing right-sided cancer," said Dr Vivek Kaul, acting ranking of gastroenterology and hepatology at the University of Rochester Medical Center. "Here is a thesis that suggests that risk reduction is pretty robust even in the right side. The imperil reduction is not as exciting as in the left side, but it's still more than 50 percent. That's a little tyrannical to ignore".

The news is "reassuring," agreed Dr David Weinberg, chairman of medicine at Fox Chase Cancer Center in Philadelphia, who wrote an accompanying article on the finding. Though no one bookwork ever provides definitive proof "if the data from this study is in fact true, then this gives strong countenance for current guidelines".

The American Cancer Society recommends that normal-risk men and women be screened for colon cancer, starting at era 50. A colonoscopy once every 10 years is one of the recommended screening tools. However, there has been some contend as to whether colonoscopy - an invasive and expensive procedure - is absolutely preferable to other screening methods, such as flexible sigmoidoscopy.

Sunday, 1 December 2019

A New Factor Of Increasing The Risk Of Colon Cancer Was Studied

A New Factor Of Increasing The Risk Of Colon Cancer Was Studied.
Researchers article that expensive levels of a protein measured through blood tests could be a cypher that patients are at higher risk of colon cancer. And another new reflect on finds that in blacks, a common germ boosts the risk of colorectal polyps - offbeat tissue growths in the colon that often become cancerous.

Both studies are slated to be presented Monday at the American Association for Cancer Research (AACR) annual encounter in Washington, DC. One study links important levels of circulating C-reactive protein to a higher risk of colon cancer. Protein levels take to the air when there's low-grade inflammation in the body.

So "Elevated CRP levels may be considered as a jeopardy marker, but not necessarily a cause, for the carcinogenic process of colon cancer," Dr Gong Yang, enquiry associate professor at Vanderbilt University, said in an AACR news release. Yang and colleagues intentional 338 cases of colorectal cancer among participants in the Shanghai Women's Health Study and compared them to 451 women without the disease.

Women whose protein levels were in the highest post had a 2,5 - shut down higher risk of colon cancer compared to those in the lowest quarter. In the other study, researchers linked the bacterium Helicobacter pylori to a higher gamble of colorectal polyps in blacks. That could press it more likely that they'll develop colon cancer.

But "Not each and every one gets sick from H pylori infection, and there is a legitimate concern about overusing antibiotics to touch on it," said Dr Duane T Smoot, chief of the gastrointestinal allotment at Howard University, in a statement. However, the majority of the time these polyps will become cancerous if not removed, so we basic to screen for the bacteria and treat it as a possible cancer prevention strategy. The learning authors, who examined the medical records of 1262 black patients, found that the polyps were 50 percent more omnipresent in those who were infected with H pylori.

Friday, 9 March 2018

Early Diagnostics Of A Colorectal Cancer

Early Diagnostics Of A Colorectal Cancer.
Researchers in South Korea stipulate they've developed a blood proof that spots genetic changes that signal the manifestation of colon cancer, April 2013. The test accurately spotted 87 percent of colon cancers across all cancer stages, and also correctly identified 95 percent of patients who were cancer-free, the researchers said. Colon cancer remains the assistant matchless cancer lollapalooza in the United States, after lung cancer. According to the US Centers for Disease Control and Prevention, nearly 137000 Americans were diagnosed with the infirmity in 2009; 40 percent of people diagnosed will stop from the disease.

Right now, invasive colonoscopy remains the "gold standard" for spotting cancer early, although fecal inexplicable blood testing (using stool samples) also is used. What's needed is a greatly accurate but noninvasive testing method, experts say. The new blood assess looks at the "methylation" of genes, a biochemical process that is key to how genes are expressed and function. Investigators from Genomictree Inc and Yonsei University College of Medicine in Seoul said they spotted a set of genes with patterns of methylation that seems to be set to tissues from colon cancer tumors.

Changes in one gene in particular, called SDC2, seemed especially tied to colon cancer swelling and spread. As reported in the July 2013 result of the Journal of Molecular Diagnostics, the party tested the gene-based vet in tissues taken from 133 colon cancer patients. As expected, tissues entranced from colon cancer tumors in these patients showed the characteristic gene changes, while samples enchanted from adjacent healthy tissues did not.

More important, the same genetic hallmarks of colon cancer (or their absence) "could be intentional in blood samples from colorectal cancer patients and healthy individuals," the researchers said in a minutes news release. The test was able to detect stage 1 cancer 92 percent of the time, "indicating that SDC2 is acceptable for early detection of colorectal cancer where therapeutical interventions have the greatest likelihood of curing the patient from the disease," study example author TaeJeong Oh said in the news release.

Wednesday, 27 December 2017

New Non Invasive Test For Detection Of Tumors Of The Colon Is More Accurate Than Previously Used

New Non Invasive Test For Detection Of Tumors Of The Colon Is More Accurate Than Previously Used.
A additional noninvasive check-up to read pre-cancerous polyps and colon tumors appears to be more accurate than advised noninvasive tests such as the fecal occult blood test, Mayo clinic researchers say. The researching for a highly accurate, noninvasive alternative to invasive screens such as colonoscopy or sigmoidoscopy is a "Holy Grail" of colon cancer research. In a prior trial, the new try was able to identify 64 percent of pre-cancerous polyps and 85 percent of full-blown cancers, the researchers reported.

Dr Floriano Marchetti, an subordinate professor of clinical surgery in the division of colon and rectal surgery at University of Miami Sylvester Comprehensive Cancer Center, said the untrodden study could be an important adjunct to colon cancer screening if it proves itself in further study. "Obviously, these findings requisite to be replicated on a larger scale. Hopefully, this is a good start for a more reliable test".

Dr Durado Brooks, leader of colorectal cancer at the American Cancer Society, agreed. "These findings are interesting. They will be more fascinating if we ever get this kind of data in a screening population".

The study's lead researcher remained optimistic. "There are 150000 rejuvenated cases of colon cancer each year in the United States, treated at an estimated price of $14 billion," noted Dr David A Ahlquist, professor of c physic and a consultant in gastroenterology at the Mayo Clinic in Rochester, Minn. "The hallucinate is to eradicate colon cancer altogether and the most realistic approach to getting there is screening. And screening not only in a motion that would not only detect cancer, but pre-cancer. Our test takes us closer to that dream".

Ahlquist was scheduled to endowment the findings of the study Thursday in Philadelphia at a meeting on colorectal cancer sponsored by the American Association for Cancer Research. The redesigned technology, called the Cologuard sDNA test, innards by identifying specific altered DNA in cells shed by pre-cancerous or cancerous polyps into the patient's stool.

If a DNA distortion is found, a colonoscopy would still be needed to confirm the results, just as happens now after a unquestionable fecal occult blood test (FOBT) result. To see whether the test was effective, Ahlquist's group tried it out on more than 1100 frozen stool samples from patients with and without colorectal cancer.

The check was able to detect 85,3 percent of colorectal cancers and 63,8 percent of polyps bigger than 1 centimeter. Polyps this extent are considered pre-cancers and most likely to progress to cancer.

Sunday, 17 December 2017

Infection With Ascaris Eggs Relieves Symptoms Of Ulcerative Colitis

Infection With Ascaris Eggs Relieves Symptoms Of Ulcerative Colitis.
The specimen of a mankind who swallowed parasite eggs to treat his ulcerative colitis - and really got better - sheds light on how "worm therapy" might help heal the gut, a callow study suggests. "Our findings in this case report suggest that infection with the eggs of the T trichiura roundworm can alleviate the symptoms of ulcerative colitis," said weigh leader P'ng Loke, an aide professor in the department of medical parasitology at NYU Langone Medical Center. A accommodating parasite, Trichuris trichiura infects the large intestine.

The findings could also lead to additional ways to treat the debilitating disease, a form of inflammatory bowel disease (IBD) currently treated with drugs that don't always industry and can cause serious side effects, said Loke. The contemplation findings are published in the Dec 1, 2010 issue of Science Translational Medicine.

Loke and his side followed a 35-year-old man with severe colitis who tried worm (or "helminthic") psychoanalysis to avoid surgical removal of his entire colon. He researched the therapy, flew to a heal in Thailand who had agreed to give him the eggs, and swallowed 1500 of them.

The man contacted Loke after his self-treatment and "was essentially symptom-free". Intrigued, he and his colleagues sure to follow the man's condition.

The study analyzed slides and samples of the man's blood and colon web from 2003, before he swallowed the eggs, to 2009, a few years after ingestion. During this period, he was practically symptom-free for almost three years. When his colitis flared in 2008, he swallowed another 2000 eggs and got better again, said Loke.

Tissue captivated during lively colitis showed a large number of CD4+ T-cells, which are immune cells that produce the inflammatory protein interleukin-17, the yoke found. However, tissue taken after worm therapy, when his colitis was in remission, contained lots of T-cells that commission interleukin-22 (IL-22), a protein that promotes wound healing.

Friday, 15 December 2017

Colonoscopy Decreases The Potential For Colorectal Cancer On The Right Side Of The Colon Also

Colonoscopy Decreases The Potential For Colorectal Cancer On The Right Side Of The Colon Also.
In joining to reducing the jeopardize of cancer on the hand side of the colon, new research indicates that colonoscopies may also reduce cancer endanger on the right side. The finding contradicts some previous research that had indicated a right-side "blind spots" when conducting colonoscopies. However, the right-side forward shown in the new study, published in the Jan 4, 2011 edition of the Annals of Internal Medicine, was slightly less effective than that seen on the progressive side. "We didn't really have robust data proving that anything is very good at preventing right-sided cancer," said Dr Vivek Kaul, acting manager of gastroenterology and hepatology at the University of Rochester Medical Center. "Here is a typescript that suggests that risk reduction is dulcet robust even in the right side. The risk reduction is not as exciting as in the left side, but it's still more than 50 percent.

That's a miniature hard to ignore". The news is "reassuring," agreed Dr David Weinberg, chairman of c physic at Fox Chase Cancer Center in Philadelphia, who wrote an accompanying leader on the finding. Though no one study ever provides definitive proof "if the observations from this study is in fact true, then this gives strong support for current guidelines". The American Cancer Society recommends that normal-risk men and women be screened for colon cancer, starting at epoch 50.

A colonoscopy once every 10 years is one of the recommended screening tools. However, there has been some think as to whether colonoscopy - an invasive and precious procedure - is truly preferable to other screening methods, such as compliant sigmoidoscopy. Based on a review of medical records of 1,688 German patients aged 50 and over with colorectal cancer and 1,932 without, the researchers found a 77 percent reduced imperil for this breed of malignancy among people who'd had a colonoscopy in the past 10 years, as compared with those who had not.

Friday, 26 August 2016

Statins Do Not Reduce The Risk Of Colon Cancer

Statins Do Not Reduce The Risk Of Colon Cancer.
Statins don't take down the hazard of colorectal cancer, and may even increase the chances of developing precancerous polyps, unusual research suggests. Statins are widely prescribed cholesterol-lowering drugs sold in a contrast of generic forms and brand names, including Lipitor, Crestor and Zocor.

Yet, researchers stressed that the results are "not conclusive," and that man taking statins to lower cholesterol and reduce their peril of heart attack should continue taking the drugs. "We found patients in this study taking statins for more than three years tended to arise more premalignant colon lesions," said study author Dr Monica Bertagnolli, principal of the division of surgical oncology at Brigham and Women's Hospital and a professor of surgery at Harvard Medical School. "This is an gripping finding that needs to be followed up, but it should not raise alarm. No one should dam taking their statins."

The study is to be presented Monday at the American Association for Cancer Research annual engagement in Washington, DC, and it is also published online in the journal Cancer Prevention Research. The figures used in the analysis was from an earlier clinical trial to determine if the cox-2 sedative celecoxib (Celebrex) could be used to prevent colon cancer.

That trial included 2035 folk who were at high risk of colon cancer and had already been diagnosed with precancerous polyps, or adenomas. That study, published in 2006, found the celecoxib reduced the experience of adenomas, but it also more than doubled the risk of heart undertake and other serious cardiac events.