Early Mammography For Women Younger Than 50 Years With A Moderate History.
Mammograms given to women under 50 with a middle-of-the-road classification history of knocker cancer can spot cancers earlier and increase the odds for long-term survival, a new ponder shows. British researchers examined mammogram results for 6,710 women with several relatives with titty cancer, or at least one relative diagnosed before age 40, finding that 136 were diagnosed with the malignancy between 2003 and 2007. These women, who researchers said were perhaps not carriers of a mutated BRCA mamma cancer gene, started receiving mammograms at an earlier age than recommended by the UK National Health Service, which currently offers the screenings every three years for women between the ages of 50 and 70.
Findings showed their tumors were smaller and less martial than those in women screened at regular ages, and these women were more able to be alive 10 years after diagnosis of an invasive cancer, the researchers said. "We were not root and branch surprised at the findings," said lead researcher Stephen Duffy, a professor of cancer screening at Barts and The London School of Medicine and Dentistry at Queen Mary University of London.
And "There is already reveal that natives screening with mammography works in women under 50, even if it is more less effective than at later ages. However, there is evidence that women with a family history have denser tit tissue, which makes mammography a tougher job, so we were not sure what to expect. We did not explicitly remove BRCA-positive women but very few with an identified mutation were recruits, and because the women had a moderate rather than an extensive family history, we fancy there were very few cases among the vast majority who had not been tested for mutations".
Duffy juxtaposed his findings against the in the air debate among US public health experts, who disagree over whether annual mammograms are vital beginning at the age of 40, which has been the standard for years. In November 2009, the US Preventive Services Task Force sparked desecrate when it revised its mammogram recommendations, suggesting that screenings can be delayed until age 50 and be given every other year.
And "There are two issues here. The first is that there is some documentation of a mortality benefit of screening women in their 40s, albeit a lesser one than in older women. The assistant is that our study does not relate to population screening, but to mammographic surveillance of women who are concerned about their kin history of breast or ovarian cancer".
Showing posts with label history. Show all posts
Showing posts with label history. Show all posts
Sunday, 15 December 2019
Thursday, 2 March 2017
Doctors Discovered A Link Between Alcoholism And Obesity
Doctors Discovered A Link Between Alcoholism And Obesity.
People at higher endanger for alcoholism might also impression higher odds of becoming obese, new contemplate findings show. Researchers at Washington University School of Medicine in St Louis analyzed material from two large US alcoholism surveys conducted in 1991-1992 and 2001-2002. According to the results of the more fresh survey, women with a family history of alcoholism were 49 percent more liable to to be obese than other women. Men with a family history of alcoholism were also more likely to be obese, but this association was not as offensively in men as in women, said first author Richard A Grucza, an assistant professor of psychiatry.
One exegesis for the increased risk of obesity among people with a family history of alcoholism could be that some masses substitute one addiction for another. For example, after a person sees a close allied with a drinking problem, they may avoid alcohol but consume high-calorie foods that stimulate the same reward centers in the perception that react to alcohol, Grucza suggested.
In their analysis of the data from both surveys, the researchers found that the element between family history of alcoholism and obesity has grown stronger over time. This may be due to the increasing availability of foods that interact with the same percipience areas as alcohol.
People at higher endanger for alcoholism might also impression higher odds of becoming obese, new contemplate findings show. Researchers at Washington University School of Medicine in St Louis analyzed material from two large US alcoholism surveys conducted in 1991-1992 and 2001-2002. According to the results of the more fresh survey, women with a family history of alcoholism were 49 percent more liable to to be obese than other women. Men with a family history of alcoholism were also more likely to be obese, but this association was not as offensively in men as in women, said first author Richard A Grucza, an assistant professor of psychiatry.
One exegesis for the increased risk of obesity among people with a family history of alcoholism could be that some masses substitute one addiction for another. For example, after a person sees a close allied with a drinking problem, they may avoid alcohol but consume high-calorie foods that stimulate the same reward centers in the perception that react to alcohol, Grucza suggested.
In their analysis of the data from both surveys, the researchers found that the element between family history of alcoholism and obesity has grown stronger over time. This may be due to the increasing availability of foods that interact with the same percipience areas as alcohol.
Thursday, 13 February 2014
The Genetic History Of The Father Also Affect Cancers Of Female Organs
The Genetic History Of The Father Also Affect Cancers Of Female Organs.
Women with female relatives who have had tit or ovarian cancer are often acutely in the know of their own increased danger and may seek genetic counseling. But they should also pay acclaim to their father's family history, one genetic counselor warns. The inherited genetic predisposition to bust and ovarian cancer is mostly caused by a mutation in one or both of the BRCA1 or BRCA2 tumor suppressor genes, said Jeanna McCuaig, a genetic counselor at Princess Margaret Hospital in Toronto.
And, she penetrating out, "if your mom or your dad has a BRCA1 or BRCA2 mutation, you would have a 50 percent come to pass of inheriting it from either one". That explains why a father's classification history is as important to consider as a mother's, she said. "Anecdotally, I've had patients come in and say, 'I never prospect about my dad's side,'" McCuaig said. She clear to do some research into the implications of that statement. "We took two years of resolved charts referred to our clinic, referred as new patients, and looked to see how many had relatives with heart or ovarian cancers on the mom's side versus the dad," she said.
She found that patients who came to her Familial Breast and Ovarian Cancer Clinic at the health centre were more than five times more likely to be referred with a devoted family history of breast or ovarian cancer than a paternal history of such cancers. To get the vow out, she wrote a commentary on the subject, published online in The Lancet Oncology.
Women with female relatives who have had tit or ovarian cancer are often acutely in the know of their own increased danger and may seek genetic counseling. But they should also pay acclaim to their father's family history, one genetic counselor warns. The inherited genetic predisposition to bust and ovarian cancer is mostly caused by a mutation in one or both of the BRCA1 or BRCA2 tumor suppressor genes, said Jeanna McCuaig, a genetic counselor at Princess Margaret Hospital in Toronto.
And, she penetrating out, "if your mom or your dad has a BRCA1 or BRCA2 mutation, you would have a 50 percent come to pass of inheriting it from either one". That explains why a father's classification history is as important to consider as a mother's, she said. "Anecdotally, I've had patients come in and say, 'I never prospect about my dad's side,'" McCuaig said. She clear to do some research into the implications of that statement. "We took two years of resolved charts referred to our clinic, referred as new patients, and looked to see how many had relatives with heart or ovarian cancers on the mom's side versus the dad," she said.
She found that patients who came to her Familial Breast and Ovarian Cancer Clinic at the health centre were more than five times more likely to be referred with a devoted family history of breast or ovarian cancer than a paternal history of such cancers. To get the vow out, she wrote a commentary on the subject, published online in The Lancet Oncology.
Saturday, 30 November 2013
The Need For Annual Breast MRI In Addition To Annual Mammography
The Need For Annual Breast MRI In Addition To Annual Mammography.
Women who have had boob cancer should think annual screening with breast MRI in extension to an annual mammogram, new research indicates. Currently, the American Cancer Society recommends annual teat MRI plus mammography for women at very high risk for titty cancer, such as those with a known genetic mutation known as BRCA or those with a very strong family history. But it takes no post on MRI imaging for women who have had breast cancer, saying there is not enough evidence to urge one way or the other.
Studying the effectiveness of MRI screening on all three groups of women, Dr Wendy DeMartini, an aid professor of radiology at the University of Washington Medical School, said MRI imaging found proportionally more cancers in women who had been treated for chest cancer than in the women considered at very capital risk. "Women in the personal history group who had MRI were also less likely to be recalled for additional testing, and less indubitably to have a biopsy for a false positive finding," she said.
DeMartini was scheduled to present the findings Sunday at the annual caucus of the Radiological Society of North America in Chicago. For the study, her side reviewed initial breast MRI exams of 1026 women, conducted from January 2004 to June 2009. Of these, 327 had a genetic or genre history; 646 had a individual history of breast cancer that had been treated.
Women who have had boob cancer should think annual screening with breast MRI in extension to an annual mammogram, new research indicates. Currently, the American Cancer Society recommends annual teat MRI plus mammography for women at very high risk for titty cancer, such as those with a known genetic mutation known as BRCA or those with a very strong family history. But it takes no post on MRI imaging for women who have had breast cancer, saying there is not enough evidence to urge one way or the other.
Studying the effectiveness of MRI screening on all three groups of women, Dr Wendy DeMartini, an aid professor of radiology at the University of Washington Medical School, said MRI imaging found proportionally more cancers in women who had been treated for chest cancer than in the women considered at very capital risk. "Women in the personal history group who had MRI were also less likely to be recalled for additional testing, and less indubitably to have a biopsy for a false positive finding," she said.
DeMartini was scheduled to present the findings Sunday at the annual caucus of the Radiological Society of North America in Chicago. For the study, her side reviewed initial breast MRI exams of 1026 women, conducted from January 2004 to June 2009. Of these, 327 had a genetic or genre history; 646 had a individual history of breast cancer that had been treated.
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