A Brain Concussion Can Lead To Fatigue, Depression And Lack Of Libido.
Former NFL players who had concussions during their hurtle could be more disposed to to familiarity depression later in life, and athletes who racked up a lot of these head injuries could be at even higher risk, two additional studies contend. The findings are especially timely following a report last week that a capacity autopsy of former NFL player Junior Seau, who committed suicide last May, revealed signs of dyed in the wool traumatic encephalopathy, likely due to multiple hits to the head. The brawl - characterized by impulsivity, depression and erratic behavior - is only diagnosed after death.
The start of the two studies of retired athletes found that the more concussions that players reported suffering, the more expected they were to have depressive symptoms, most commonly fatigue and lack of sex drive. The second study, involving many of the same athletes, worn brain imaging to identify areas that could be involved with these symptoms, and found vast white matter damage among former players with depression.
The research, released on Jan 16, 2013 will be presented in March at the American Academy of Neurology convergence in San Diego. "We were very surprised to confer with that many of the athletes had high amounts of depressive symptoms," said Nyaz Didehbani, a delving psychologist at the Center for BrainHealth at the University of Texas at Dallas and lead prime mover of the first study.
The study included 34 retired NFL players, as well as 29 fit men who did not play football. The men's average age was about 60. All the athletes had suffered at least one concussion, with four being the average. The researchers excluded athletes who showed signs of crazy reduction such as memory problems because they wanted to study depression alone.
Overall, the former players in the swot had more depressive symptoms than the other participants, and the athletes who had more symptoms had also suffered more concussions. "The life of these depressed athletes seems to be a little different than the average population that has depression". Instead of the awful and pessimistic feelings that are often associated with depression, the athletes tend to experience symptoms such as fatigue, scarcity of sex drive and sleep changes.
And "Most of the athletes did not realize that those kinds of symptoms were interdependent to depression because, I think, they associated them with the physical pain from playing professional football". The doctors who upon former football players should let them know that fatigue and sleep problems could be symptoms of depression. "One eulogistic thing is that depression is a treatable illness".
Tuesday, 3 December 2019
Monday, 2 December 2019
Ethnic Structure Of Teachers At Medical Schools Of The USA
Ethnic Structure Of Teachers At Medical Schools Of The USA.
Despite extent initiatives, there still are too few minority potential members at US medical schools and those minorities are less in all probability to be promoted, according to a new study. Researchers analyzed data gathered from medical schools across the land between 2000 and 2010. During that time, the percentage of minority skill members increased from 6,8 percent to 8 percent. Minorities include blacks, Hispanics, Native Americans, Alaskan Natives, Native Hawaiians and Pacific Islanders.
Over the same period, the cut of newly hired minority aptitude members increased from 9,4 percent to 12,1 percent. The part of newly promoted minority faculty members increased from 6,3 percent to 7,9 percent.
Despite extent initiatives, there still are too few minority potential members at US medical schools and those minorities are less in all probability to be promoted, according to a new study. Researchers analyzed data gathered from medical schools across the land between 2000 and 2010. During that time, the percentage of minority skill members increased from 6,8 percent to 8 percent. Minorities include blacks, Hispanics, Native Americans, Alaskan Natives, Native Hawaiians and Pacific Islanders.
Over the same period, the cut of newly hired minority aptitude members increased from 9,4 percent to 12,1 percent. The part of newly promoted minority faculty members increased from 6,3 percent to 7,9 percent.
Passive Smoking May Cause Illness Of The Cardiovascular System
Passive Smoking May Cause Illness Of The Cardiovascular System.
The more you're exposed to secondhand tobacco smoke, the more promising you are to reveal early signs of pity disease, a new study indicates. The findings suggest that exposure to secondhand smoke may be more precarious than previously thought, according to the researchers. For the study, the investigators looked at nearly 3100 wholesome people, aged 40 to 80, who had never smoked and found that 26 percent of those exposed to varying levels of secondhand smoke - as an mature or child, at work or at home - had signs of coronary artery calcification, compared to 18,5 percent of the sweeping population. Those who reported higher levels of secondhand smoke risk had the greatest evidence of calcification, a build-up of calcium in the artery walls.
After taking other pump risk factors into account, the researchers concluded that people exposed to low, non-reactionary or high levels of secondhand smoke were 50, 60 and 90 percent, respectively, more conceivable to have evidence of calcification than those who had minimal exposure. The health effects of secondhand smoke on coronary artery calcification remained whether the publication was during childhood or adulthood, the results showed.
The boning up findings are scheduled for presentation Thursday at the annual meeting of the American College of Cardiology (ACC), in San Francisco. "This probing provides additional evidence that secondhand smoke is pernicious and may be even more dangerous than we previously thought," study author Dr Harvey Hecht, associate pilot of cardiac imaging and professor of medicine at Mount Sinai Medical Center in New York City, said in an ACC message release.
The more you're exposed to secondhand tobacco smoke, the more promising you are to reveal early signs of pity disease, a new study indicates. The findings suggest that exposure to secondhand smoke may be more precarious than previously thought, according to the researchers. For the study, the investigators looked at nearly 3100 wholesome people, aged 40 to 80, who had never smoked and found that 26 percent of those exposed to varying levels of secondhand smoke - as an mature or child, at work or at home - had signs of coronary artery calcification, compared to 18,5 percent of the sweeping population. Those who reported higher levels of secondhand smoke risk had the greatest evidence of calcification, a build-up of calcium in the artery walls.
After taking other pump risk factors into account, the researchers concluded that people exposed to low, non-reactionary or high levels of secondhand smoke were 50, 60 and 90 percent, respectively, more conceivable to have evidence of calcification than those who had minimal exposure. The health effects of secondhand smoke on coronary artery calcification remained whether the publication was during childhood or adulthood, the results showed.
The boning up findings are scheduled for presentation Thursday at the annual meeting of the American College of Cardiology (ACC), in San Francisco. "This probing provides additional evidence that secondhand smoke is pernicious and may be even more dangerous than we previously thought," study author Dr Harvey Hecht, associate pilot of cardiac imaging and professor of medicine at Mount Sinai Medical Center in New York City, said in an ACC message release.
Blueberries And Strawberries To Reduce The Risk Of Heart Attack
Blueberries And Strawberries To Reduce The Risk Of Heart Attack.
Eating three or more servings of blueberries and strawberries each week may staff downgrade a woman's peril of heart attack, a large new study suggests. The study included nearly 94000 infantile and middle-aged women who took part in the Nurses' Health Study II. The women completed questionnaires about their aliment every four years for 18 years. During the workroom period, 405 participants had heart attacks. Women who ate the most blueberries and strawberries were 32 percent less favourite to have a heart attack, compared to women who ate berries once a month or less.
This held steady even among women who ate a diet rich in other fruits and vegetables. This aid was independent of other heart risk factors such as advancing age, high blood pressure, folks history of heart attack, body mass index, exercise, smoking, and caffeine and spirits intake. The findings appear online Jan 14, 2013 in the journal Circulation.
The learn can't say specifically what about the berries seemed to result in a lower risk of heart denigrate among these women, or that there was a direct cause-and-effect link between eating the berries and lowered heart set risk. But blueberries and strawberries contain high levels of compounds that may help add to arteries, which counters plaque buildup, the researchers said.
Heart attacks can occur when plaque blocks blood ripple to the heart. "Berries were the most commonly consumed sources of these substances in the US diet, and they are one of the best sources of these dynamic bioactive compounds," said study lead author Aedin Cassidy. "These substances, called anthocyanins - a flavonoid - are plainly present in red- and blue-colored fruits and vegetables, so they are also found in ripe amounts in cherries, grapes, eggplant, black currants, plums and other berries".
Eating three or more servings of blueberries and strawberries each week may staff downgrade a woman's peril of heart attack, a large new study suggests. The study included nearly 94000 infantile and middle-aged women who took part in the Nurses' Health Study II. The women completed questionnaires about their aliment every four years for 18 years. During the workroom period, 405 participants had heart attacks. Women who ate the most blueberries and strawberries were 32 percent less favourite to have a heart attack, compared to women who ate berries once a month or less.
This held steady even among women who ate a diet rich in other fruits and vegetables. This aid was independent of other heart risk factors such as advancing age, high blood pressure, folks history of heart attack, body mass index, exercise, smoking, and caffeine and spirits intake. The findings appear online Jan 14, 2013 in the journal Circulation.
The learn can't say specifically what about the berries seemed to result in a lower risk of heart denigrate among these women, or that there was a direct cause-and-effect link between eating the berries and lowered heart set risk. But blueberries and strawberries contain high levels of compounds that may help add to arteries, which counters plaque buildup, the researchers said.
Heart attacks can occur when plaque blocks blood ripple to the heart. "Berries were the most commonly consumed sources of these substances in the US diet, and they are one of the best sources of these dynamic bioactive compounds," said study lead author Aedin Cassidy. "These substances, called anthocyanins - a flavonoid - are plainly present in red- and blue-colored fruits and vegetables, so they are also found in ripe amounts in cherries, grapes, eggplant, black currants, plums and other berries".
Vitamin B12 Affects Fractures
Vitamin B12 Affects Fractures.
Older men with ineffective levels of vitamin B-12 are at increased jeopardize for bone fractures, a new study suggests. Researchers measured the levels of vitamin B-12 in 1000 Swedish men with an middling age of 75. They found that participants with gentle levels of the vitamin were more likely than those with normal levels to have suffered a fracture. Men in the league with the lowest B-12 levels were about 70 percent more likely to have suffered a fracture than others in the contemplation Dec 2013.
This increased risk was primarily due to fractures in the lumbar spine, where there was an up to 120 percent greater unplanned of fractures. "The higher risk also remains when we take other risk factors for fractures into consideration, such as age, smoking, weight, bone-mineral density, untimely fractures, concrete activity, the vitamin D content in the blood and calcium intake," study author Catharina Lewerin, a researcher at the Sahlgrenska Academy at the University of Gothenburg, in Sweden, said in a university copy release.
Older men with ineffective levels of vitamin B-12 are at increased jeopardize for bone fractures, a new study suggests. Researchers measured the levels of vitamin B-12 in 1000 Swedish men with an middling age of 75. They found that participants with gentle levels of the vitamin were more likely than those with normal levels to have suffered a fracture. Men in the league with the lowest B-12 levels were about 70 percent more likely to have suffered a fracture than others in the contemplation Dec 2013.
This increased risk was primarily due to fractures in the lumbar spine, where there was an up to 120 percent greater unplanned of fractures. "The higher risk also remains when we take other risk factors for fractures into consideration, such as age, smoking, weight, bone-mineral density, untimely fractures, concrete activity, the vitamin D content in the blood and calcium intake," study author Catharina Lewerin, a researcher at the Sahlgrenska Academy at the University of Gothenburg, in Sweden, said in a university copy release.
Smokers' Lung Malignant Tumor Can Contain Up To 50000 Genetic Mutations
Smokers' Lung Malignant Tumor Can Contain Up To 50000 Genetic Mutations.
Malignant lung tumors may restrict not one, not two, but potentially tens of thousands of genetic mutations which, together, provide to the phenomenon of the cancer. A swatch from a lung tumor from a heavy smoker revealed 50000 mutations, according to a report in the May 27 pour of Nature. "People in the field have always known that we're going to end up having to deal with multiple mutations," said Dr Hossein Borghaei, the man of the Lung and Head and Neck Cancer Risk Assessment Program at Fox Chase Cancer Center in Philadelphia. "This tells us that we're not just dealing with one room pitch that's gone crazy.
We're dealing with multiple mutations. Every admissible pathway that could possibly go wrong is probably found among all these mutations and changes". The revelation does pretence "additional difficulties" for researchers looking for targets for better treatments or even a cure for lung and other types of cancer, said analyse senior author Zemin Zhang, a senior scientist with Genentech Inc in South San Francisco.
Frustrating though the findings may seem, the education gleaned from this and other studies "gives investigators a starting cape to go back and look and see if there is a common pathway, a common protein that a couple of opposite drugs could attack and perhaps slow the progression". The researchers examined cells from lung cancer samples (non-small-cell lung cancer) connection to a 51-year-old man who had smoked 25 cigarettes a prime for 15 years.
Malignant lung tumors may restrict not one, not two, but potentially tens of thousands of genetic mutations which, together, provide to the phenomenon of the cancer. A swatch from a lung tumor from a heavy smoker revealed 50000 mutations, according to a report in the May 27 pour of Nature. "People in the field have always known that we're going to end up having to deal with multiple mutations," said Dr Hossein Borghaei, the man of the Lung and Head and Neck Cancer Risk Assessment Program at Fox Chase Cancer Center in Philadelphia. "This tells us that we're not just dealing with one room pitch that's gone crazy.
We're dealing with multiple mutations. Every admissible pathway that could possibly go wrong is probably found among all these mutations and changes". The revelation does pretence "additional difficulties" for researchers looking for targets for better treatments or even a cure for lung and other types of cancer, said analyse senior author Zemin Zhang, a senior scientist with Genentech Inc in South San Francisco.
Frustrating though the findings may seem, the education gleaned from this and other studies "gives investigators a starting cape to go back and look and see if there is a common pathway, a common protein that a couple of opposite drugs could attack and perhaps slow the progression". The researchers examined cells from lung cancer samples (non-small-cell lung cancer) connection to a 51-year-old man who had smoked 25 cigarettes a prime for 15 years.
Sunday, 1 December 2019
Node Negative Breast Cancer Is Better Treated By Chemotherapy
Node Negative Breast Cancer Is Better Treated By Chemotherapy.
A chemotherapy regimen already proven higher-level to other regimens for teat cancer that has spread to the lymph nodes may also plough better for some women whose cancers haven't spread, a new study has found. When it came to these "node-negative" cancers, the numb combination of docetaxel, doxorubicin and cyclophosphamide (dubbed TAC) outperformed the trust of fluorouracil, doxorubicin, and cyclophosphamide (FAC), the Spanish study authors said. The TAC regimen was better at keeping women swarming and disease-free after a median follow up of almost six and a half years, the con found.
So "For those women with higher-risk, node-negative breast cancer, in which chemotherapy is indicated, TAC is one of the most attractive options," said study co-author Dr Miguel Martin, a professor of medical oncology at the Hospital General Universitario Gregorio Maranon in Madrid. The analysis was funded by the knock out maker Sanofi-Aventis - which makes Taxotere, the brand name for docetaxel - and GEICAM, the Spanish Breast Cancer Research Group. The results are published in the Dec 2, 2010 appear of the New England Journal of Medicine.
To adjudge which women with bust cancer would benefit from adjuvant chemotherapy (typically chemotherapy after surgery), doctors undertake into account a number of risk factors, such as the patient's age, tumor size and other characteristics. For the unknown study, the researchers assigned 1060 women with breast cancers that were axillary-node pessimistic who had at least one high-risk factor for recurrence to one of the two treatment regimens every three weeks for six cycles after their surgery.
At the 77-month mark, almost 88 percent of the TAC women were animated and disease-free, compared to buddy-buddy to 82 percent of the women in the FAC group. Those in the TAC aggregation had a 32 percent reduction in the risk of recurrence, the study authors said. The reduced peril held true even after taking into account a number of high-risk factors, such as age, the women's menopausal eminence and tumor characteristics.
A chemotherapy regimen already proven higher-level to other regimens for teat cancer that has spread to the lymph nodes may also plough better for some women whose cancers haven't spread, a new study has found. When it came to these "node-negative" cancers, the numb combination of docetaxel, doxorubicin and cyclophosphamide (dubbed TAC) outperformed the trust of fluorouracil, doxorubicin, and cyclophosphamide (FAC), the Spanish study authors said. The TAC regimen was better at keeping women swarming and disease-free after a median follow up of almost six and a half years, the con found.
So "For those women with higher-risk, node-negative breast cancer, in which chemotherapy is indicated, TAC is one of the most attractive options," said study co-author Dr Miguel Martin, a professor of medical oncology at the Hospital General Universitario Gregorio Maranon in Madrid. The analysis was funded by the knock out maker Sanofi-Aventis - which makes Taxotere, the brand name for docetaxel - and GEICAM, the Spanish Breast Cancer Research Group. The results are published in the Dec 2, 2010 appear of the New England Journal of Medicine.
To adjudge which women with bust cancer would benefit from adjuvant chemotherapy (typically chemotherapy after surgery), doctors undertake into account a number of risk factors, such as the patient's age, tumor size and other characteristics. For the unknown study, the researchers assigned 1060 women with breast cancers that were axillary-node pessimistic who had at least one high-risk factor for recurrence to one of the two treatment regimens every three weeks for six cycles after their surgery.
At the 77-month mark, almost 88 percent of the TAC women were animated and disease-free, compared to buddy-buddy to 82 percent of the women in the FAC group. Those in the TAC aggregation had a 32 percent reduction in the risk of recurrence, the study authors said. The reduced peril held true even after taking into account a number of high-risk factors, such as age, the women's menopausal eminence and tumor characteristics.
E-Mail Reminder To The Survey
E-Mail Reminder To The Survey.
Both electronic and mailed reminders assistance support some patients to get colorectal cancer screenings, two new studies show. One look included 1103 patients, aged 50 to 75, at a group tradition who were overdue for colorectal cancer screening. Half of them received a single electronic message from their doctor, along with a vinculum to a Web-based tool to assess their risk for colorectal cancer. The other patients acted as a mastery group and did not receive any electronic messages. One month later, the screening rates were 8,3 percent for patients who received the electronic reminders and 0,2 percent in the knob group.
But the characteristic was no longer significant after four months - 15,8 percent vs 13,1 percent. Among the 552 patients who received the electronic message, 54 percent viewed it and 9 percent worn the Web-based assessment tool. About one-fifth of the patients who utilized the assessment carve were estimated to have a higher-than-average risk for colorectal cancer.
Patients who used the risk tool were more expected to get screened. "Patients have expressed interest in interacting with their medical record using electronic portals comparable to the one used in our intervention," wrote Dr Thomas D Sequist, Brigham and Women's Hospital and Harvard Medical School, and colleagues, in a message release.
Both electronic and mailed reminders assistance support some patients to get colorectal cancer screenings, two new studies show. One look included 1103 patients, aged 50 to 75, at a group tradition who were overdue for colorectal cancer screening. Half of them received a single electronic message from their doctor, along with a vinculum to a Web-based tool to assess their risk for colorectal cancer. The other patients acted as a mastery group and did not receive any electronic messages. One month later, the screening rates were 8,3 percent for patients who received the electronic reminders and 0,2 percent in the knob group.
But the characteristic was no longer significant after four months - 15,8 percent vs 13,1 percent. Among the 552 patients who received the electronic message, 54 percent viewed it and 9 percent worn the Web-based assessment tool. About one-fifth of the patients who utilized the assessment carve were estimated to have a higher-than-average risk for colorectal cancer.
Patients who used the risk tool were more expected to get screened. "Patients have expressed interest in interacting with their medical record using electronic portals comparable to the one used in our intervention," wrote Dr Thomas D Sequist, Brigham and Women's Hospital and Harvard Medical School, and colleagues, in a message release.
A New Factor Of Increasing The Risk Of Colon Cancer Was Studied
A New Factor Of Increasing The Risk Of Colon Cancer Was Studied.
Researchers article that expensive levels of a protein measured through blood tests could be a cypher that patients are at higher risk of colon cancer. And another new reflect on finds that in blacks, a common germ boosts the risk of colorectal polyps - offbeat tissue growths in the colon that often become cancerous.
Both studies are slated to be presented Monday at the American Association for Cancer Research (AACR) annual encounter in Washington, DC. One study links important levels of circulating C-reactive protein to a higher risk of colon cancer. Protein levels take to the air when there's low-grade inflammation in the body.
So "Elevated CRP levels may be considered as a jeopardy marker, but not necessarily a cause, for the carcinogenic process of colon cancer," Dr Gong Yang, enquiry associate professor at Vanderbilt University, said in an AACR news release. Yang and colleagues intentional 338 cases of colorectal cancer among participants in the Shanghai Women's Health Study and compared them to 451 women without the disease.
Women whose protein levels were in the highest post had a 2,5 - shut down higher risk of colon cancer compared to those in the lowest quarter. In the other study, researchers linked the bacterium Helicobacter pylori to a higher gamble of colorectal polyps in blacks. That could press it more likely that they'll develop colon cancer.
But "Not each and every one gets sick from H pylori infection, and there is a legitimate concern about overusing antibiotics to touch on it," said Dr Duane T Smoot, chief of the gastrointestinal allotment at Howard University, in a statement. However, the majority of the time these polyps will become cancerous if not removed, so we basic to screen for the bacteria and treat it as a possible cancer prevention strategy. The learning authors, who examined the medical records of 1262 black patients, found that the polyps were 50 percent more omnipresent in those who were infected with H pylori.
Researchers article that expensive levels of a protein measured through blood tests could be a cypher that patients are at higher risk of colon cancer. And another new reflect on finds that in blacks, a common germ boosts the risk of colorectal polyps - offbeat tissue growths in the colon that often become cancerous.
Both studies are slated to be presented Monday at the American Association for Cancer Research (AACR) annual encounter in Washington, DC. One study links important levels of circulating C-reactive protein to a higher risk of colon cancer. Protein levels take to the air when there's low-grade inflammation in the body.
So "Elevated CRP levels may be considered as a jeopardy marker, but not necessarily a cause, for the carcinogenic process of colon cancer," Dr Gong Yang, enquiry associate professor at Vanderbilt University, said in an AACR news release. Yang and colleagues intentional 338 cases of colorectal cancer among participants in the Shanghai Women's Health Study and compared them to 451 women without the disease.
Women whose protein levels were in the highest post had a 2,5 - shut down higher risk of colon cancer compared to those in the lowest quarter. In the other study, researchers linked the bacterium Helicobacter pylori to a higher gamble of colorectal polyps in blacks. That could press it more likely that they'll develop colon cancer.
But "Not each and every one gets sick from H pylori infection, and there is a legitimate concern about overusing antibiotics to touch on it," said Dr Duane T Smoot, chief of the gastrointestinal allotment at Howard University, in a statement. However, the majority of the time these polyps will become cancerous if not removed, so we basic to screen for the bacteria and treat it as a possible cancer prevention strategy. The learning authors, who examined the medical records of 1262 black patients, found that the polyps were 50 percent more omnipresent in those who were infected with H pylori.
Saturday, 30 November 2019
Menopause Affects Women Differently
Menopause Affects Women Differently.
Women bothered by blether flashes or other crap of menopause have a number of treatment options - hormonal or not, according to updated guidelines from the American College of Obstetricians and Gynecologists. It's estimated that anywhere from 50 percent to 82 percent of women effective through menopause have recent flashes - sudden feelings of extreme intensity in the upper body - and night sweats. For many, the symptoms are frequent and severe enough to cause repose problems and disrupt their daily lives.
And the duration of the misery can last from a couple years to more than a decade, says the college, the nation's influential group of ob/gyns. "Menopausal symptoms are common, and can be very bothersome to women," said Dr Clarisa Gracia, who helped put in writing the new guidelines. "Women should grasp that effective treatments are available to address these symptoms". The guidelines, published in the January outlet of Obstetrics andamp; Gynecology, reinforce some longstanding advice: Hormone therapy, with estrogen by oneself or estrogen plus progestin, is the most effective way to cool hot flashes.
But they also advance out the growing evidence that some antidepressants can help an associate professor of obstetrics and gynecology at the University of Pennsylvania in Philadelphia. In studies, down doses of antidepressants such as venlafaxine (Effexor) and fluoxetine (Prozac) have helped spell hot flashes in some women. And two other drugs - the anti-seizure cure gabapentin and the blood pressure medication clonidine - can be effective, according to the guidelines.
So far, though, only one non-hormonal anaesthetize is actually approved by the US Food and Drug Administration for treating brilliant flashes: a low-dose version of the antidepressant paroxetine (Paxil). And experts said that while there is manifest some hormone alternatives ease hot flashes, none works as well as estrogen and estrogen-progestin. "Unfortunately, many providers are white-livered to prescribe hormones.
And a lot of the time, women are fearful," said Dr Patricia Sulak, an ob/gyn at Scott andamp; White Hospital in Temple, Texas, who was not affected in calligraphy the new guidelines. Years ago, doctors routinely prescribed hormone replacement analysis after menopause to lower women's risk of heart disease, among other things. But in 2002, a colossal US trial called the Women's Health Initiative found that women given estrogen-progestin pills really had slightly increased risks of blood clots, heart attack and breast cancer. "Use of hormones plummeted" after that.
Women bothered by blether flashes or other crap of menopause have a number of treatment options - hormonal or not, according to updated guidelines from the American College of Obstetricians and Gynecologists. It's estimated that anywhere from 50 percent to 82 percent of women effective through menopause have recent flashes - sudden feelings of extreme intensity in the upper body - and night sweats. For many, the symptoms are frequent and severe enough to cause repose problems and disrupt their daily lives.
And the duration of the misery can last from a couple years to more than a decade, says the college, the nation's influential group of ob/gyns. "Menopausal symptoms are common, and can be very bothersome to women," said Dr Clarisa Gracia, who helped put in writing the new guidelines. "Women should grasp that effective treatments are available to address these symptoms". The guidelines, published in the January outlet of Obstetrics andamp; Gynecology, reinforce some longstanding advice: Hormone therapy, with estrogen by oneself or estrogen plus progestin, is the most effective way to cool hot flashes.
But they also advance out the growing evidence that some antidepressants can help an associate professor of obstetrics and gynecology at the University of Pennsylvania in Philadelphia. In studies, down doses of antidepressants such as venlafaxine (Effexor) and fluoxetine (Prozac) have helped spell hot flashes in some women. And two other drugs - the anti-seizure cure gabapentin and the blood pressure medication clonidine - can be effective, according to the guidelines.
So far, though, only one non-hormonal anaesthetize is actually approved by the US Food and Drug Administration for treating brilliant flashes: a low-dose version of the antidepressant paroxetine (Paxil). And experts said that while there is manifest some hormone alternatives ease hot flashes, none works as well as estrogen and estrogen-progestin. "Unfortunately, many providers are white-livered to prescribe hormones.
And a lot of the time, women are fearful," said Dr Patricia Sulak, an ob/gyn at Scott andamp; White Hospital in Temple, Texas, who was not affected in calligraphy the new guidelines. Years ago, doctors routinely prescribed hormone replacement analysis after menopause to lower women's risk of heart disease, among other things. But in 2002, a colossal US trial called the Women's Health Initiative found that women given estrogen-progestin pills really had slightly increased risks of blood clots, heart attack and breast cancer. "Use of hormones plummeted" after that.
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