Contrave, A New Weight Loss Pill Combines Anti-Addiction Medication And An Antidepressant.
An dexterous monitory panel recommended on Tuesday that Contrave, a unknown weight-loss pill that combines an antidepressant with an anti-addiction medication, be approved by the US Food and Drug Administration. The 13-7 preference in favor of Contrave came amid agency concerns that the numb might raise blood pressure in some patients and increase the risk of heart attacks and strokes centre of some users, according to the Associated Press. But panelists voted 11-8 earlier in the heyday that those potential health risks could be studied after Contrave was approved.
The FDA does not have to follow the advice of its advisory committees, but it typically does. The mechanism is expected to make a decision on Contrave by Jan 31, 2011, the wire utilization reported. Contrave is manufactured by Orexigen Therapeutics Inc. In October, the FDA voted against approving two other weight-loss drugs, Arena Pharmaceuticals' lorcaserin and Vivus' Qnexa, because of cover concerns, according to the AP. Last July, a muse about funded by Orexigen and published in The Lancet found that Contrave helped users pour pounds when taken along with a well diet and exercise.
People who took the drug for more than a year lost an average of 5 percent or more of body weight, depending on the dosage used, the team said. However, the regimen did come with side effects, and about half of scan participants dropped out before completing a year of treatment. Contrave is combination of two familiar drugs, naltrexone (Revia, used to fight addictions) and the antidepressant bupropion (known by a host of names, including Wellbutrin).
The drug appears to boost weight loss by changing the workings of the body's essential nervous system, the researchers said. The study enrolled men (15 percent) and women (85 percent) from around the country, ranging in epoch from 18 to 65. They were all either pudgy or overweightm, with high blood fat levels or high blood pressure.
Thursday 16 January 2020
Treatment Of Heart Attack With The Help Of Stem Cells From Belly Fat
Treatment Of Heart Attack With The Help Of Stem Cells From Belly Fat.
Stem cells enchanted from the belly unctuous of 10 love attack patients managed to improve several measures of heart function, Dutch researchers report. This is the premier time this type of therapy has been used in humans, said the scientists, who presented their findings Tuesday at the American Heart Association's annual gathering in Chicago. But the improvements, though to some degree dramatic in this small group of patients, were not statistically significant, probably due to the minimal number of participants in the study.
And another expert urged caution when interpreting the results. "The opener issue is whether a treatment makes us live longer or feel better," said Dr Jeffrey S Borer, rocking-chair of the department of medicine and of cardiovascular medicine at the State University of New York (SUNY) Downstate Medical Center in New York City. This workroom only looked at "surrogates," import measures of heart function that might predict better future health in the patient.
So "This cannot be interpreted as if they instantly represent positive clinical outcomes. These certainly are reassuring stem cell data, but there's a great deal more to do before it is possible to know whether this is a viable therapy".
Another caveat: All the patients in this experimental were white Europeans. The study authors believe the results could be extrapolated to much of the US population, but not unavoidably to people who aren't white. Fat tissue yields many more stem-post cells than bone marrow (which has been studied before) and is much easier to access.
In bone marrow, 40 cubic centimeters (cc) typically revenue about 25000 stem cells, which is "not nearly enough to treat men and women with," said study author Dr Eric Duckers, head of the Molecular Cardiology Laboratory at Thoraxcenter, Erasmus University Medical Center in Rotterdam. To get enough cells to exert oneself with, those arrest cells would have to be cultured, a process that can take six to eight weeks.
Stem cells enchanted from the belly unctuous of 10 love attack patients managed to improve several measures of heart function, Dutch researchers report. This is the premier time this type of therapy has been used in humans, said the scientists, who presented their findings Tuesday at the American Heart Association's annual gathering in Chicago. But the improvements, though to some degree dramatic in this small group of patients, were not statistically significant, probably due to the minimal number of participants in the study.
And another expert urged caution when interpreting the results. "The opener issue is whether a treatment makes us live longer or feel better," said Dr Jeffrey S Borer, rocking-chair of the department of medicine and of cardiovascular medicine at the State University of New York (SUNY) Downstate Medical Center in New York City. This workroom only looked at "surrogates," import measures of heart function that might predict better future health in the patient.
So "This cannot be interpreted as if they instantly represent positive clinical outcomes. These certainly are reassuring stem cell data, but there's a great deal more to do before it is possible to know whether this is a viable therapy".
Another caveat: All the patients in this experimental were white Europeans. The study authors believe the results could be extrapolated to much of the US population, but not unavoidably to people who aren't white. Fat tissue yields many more stem-post cells than bone marrow (which has been studied before) and is much easier to access.
In bone marrow, 40 cubic centimeters (cc) typically revenue about 25000 stem cells, which is "not nearly enough to treat men and women with," said study author Dr Eric Duckers, head of the Molecular Cardiology Laboratory at Thoraxcenter, Erasmus University Medical Center in Rotterdam. To get enough cells to exert oneself with, those arrest cells would have to be cultured, a process that can take six to eight weeks.
Repeated Brain Concussion Can Lead To Disability
Repeated Brain Concussion Can Lead To Disability.
After taking a distressingly hit to the perceptiveness during a football game, an Indiana high school student suffered severe headaches for the next three days. Following a crescendo CT scan that was normal, his doctor told him to respite to go back on the field until he felt better. But the boy returned to practice, where he suffered a devastating brains injury called second impact syndrome. More than six years later, Cody Lehe, now 23, is mostly wheelchair-bound and struggles with diminished mad capacity.
Yet he's fortunate to be alive: Second modify syndrome is fatal in about 85 percent of cases. "It's a unique syndrome of sense injury that appears in high school and younger athletes when they have a mild concussion, and then have a bat head impact before they're over the symptoms of their first impact. This leads to massive knowledge swelling almost immediately," said Dr Michael Turner, a neurosurgeon at Goodman Campbell Brain and Spine at the Indiana University School of Medicine, and co-author of a rejuvenated report on Cody's case, published Jan. 1 in the Journal of Neurosurgery: Pediatrics.
The casing study illustrates why it's so notable to prevent a second impact and give a young brain the chance to rest and recover, another wizard said. "Second impact syndrome is a very rare phenomenon. It's estimated to occur about five times a year in the country," said Kenneth Podell, a neuropsychologist and co-director of the Methodist Concussion Center in Houston.
So "What makes this deliberate over unique: They're the initially ones to in actuality have a CT scan after the first hit. What they were able to show is that the first CT scan was read as normal," said Podell, who also is a rig consultant for the Houston Texans, of the NFL. "After the first concussion there was no clue of any significant injury.
After taking a distressingly hit to the perceptiveness during a football game, an Indiana high school student suffered severe headaches for the next three days. Following a crescendo CT scan that was normal, his doctor told him to respite to go back on the field until he felt better. But the boy returned to practice, where he suffered a devastating brains injury called second impact syndrome. More than six years later, Cody Lehe, now 23, is mostly wheelchair-bound and struggles with diminished mad capacity.
Yet he's fortunate to be alive: Second modify syndrome is fatal in about 85 percent of cases. "It's a unique syndrome of sense injury that appears in high school and younger athletes when they have a mild concussion, and then have a bat head impact before they're over the symptoms of their first impact. This leads to massive knowledge swelling almost immediately," said Dr Michael Turner, a neurosurgeon at Goodman Campbell Brain and Spine at the Indiana University School of Medicine, and co-author of a rejuvenated report on Cody's case, published Jan. 1 in the Journal of Neurosurgery: Pediatrics.
The casing study illustrates why it's so notable to prevent a second impact and give a young brain the chance to rest and recover, another wizard said. "Second impact syndrome is a very rare phenomenon. It's estimated to occur about five times a year in the country," said Kenneth Podell, a neuropsychologist and co-director of the Methodist Concussion Center in Houston.
So "What makes this deliberate over unique: They're the initially ones to in actuality have a CT scan after the first hit. What they were able to show is that the first CT scan was read as normal," said Podell, who also is a rig consultant for the Houston Texans, of the NFL. "After the first concussion there was no clue of any significant injury.
Women Suffer Postpartum Depression
Women Suffer Postpartum Depression.
Having a longer pregnancy leave reduces a woman's jeopardize of postpartum depression, new research shows. The findings suggest that the climactic 12 weeks of maternity leave given to American mothers under federal law may be inadequate, according to the University of Maryland researchers. "In the United States, most working women are back to fashion soon after giving birth, with the lion's share not taking more than three months of leave," study leader Dr Rada Dagher said in a university message release. "But our study showed that women who return to work sooner than six months after childbirth have an increased gamble of postpartum depressive symptoms," added Dagher, an assistant professor of vigour services administration at the School of Public Health.
In the year after giving birth, about 13 percent of mothers knowledge postpartum depression, which can cause serious symptoms similar to clinical depression. This consider included more than 800 women in Minnesota who were followed for a year after they gave birth. About 7 percent of the mothers went back to develop within six weeks, 46 percent by 12 weeks, and 87 percent by six months.
Having a longer pregnancy leave reduces a woman's jeopardize of postpartum depression, new research shows. The findings suggest that the climactic 12 weeks of maternity leave given to American mothers under federal law may be inadequate, according to the University of Maryland researchers. "In the United States, most working women are back to fashion soon after giving birth, with the lion's share not taking more than three months of leave," study leader Dr Rada Dagher said in a university message release. "But our study showed that women who return to work sooner than six months after childbirth have an increased gamble of postpartum depressive symptoms," added Dagher, an assistant professor of vigour services administration at the School of Public Health.
In the year after giving birth, about 13 percent of mothers knowledge postpartum depression, which can cause serious symptoms similar to clinical depression. This consider included more than 800 women in Minnesota who were followed for a year after they gave birth. About 7 percent of the mothers went back to develop within six weeks, 46 percent by 12 weeks, and 87 percent by six months.
Wednesday 15 January 2020
In Any Case, And Age, The Helmet Will Make The Race Safer
In Any Case, And Age, The Helmet Will Make The Race Safer.
As summer approaches and many Americans quail to dust off their bikes, blades and assorted motorized vehicles, the nation's predicament unit doctors are trying to unqualified public attention toward the importance of wearing safety helmets to prevent serious brain injury. "People are riding bicycles, motorcycles and ATVs all-terrain vehicles more often at this ease of year," Dr Angela Gardner, president of the American College of Emergency Physicians (ACEP), said in a communication release. She stressed that bourgeoisie need to get in the habit of wearing a certified safety helmet, because it only takes one distressing crash to end a life or cause serious life-altering brain injuries.
Citing National Highway Transportation Safety Administration (NHTSA) statistics, the ACEP experts note that every year more than 300000 children are rushed to the difficulty worry as a result of injuries sustained while riding a bike. Wearing a helmet that meets Consumer Product Safety Commission standards could ease this figure by more than two-thirds, the combine suggests.
But children aren't the only ones who need to wear helmets. In fact, older riders merit for 75 percent of bicycle injury deaths, the ACEP noted. Among bicyclists of all ages, 540000 endeavour emergency care each year as a result of an accident, and 67000 of these patients allow head injuries. About 40 percent experience head trauma so acute that hospitalization is required.
A properly fitted helmet can prevent brain injury 90 percent of the time, according to the NHTSA, and if all bicyclists between the ages of 4 and 15 wore a helmet, between 39000 and 45000 proceed injuries could be prevented each year. With May designated as motorcycle refuge month, the ACEP is also highlighting the benefits of helmet use middle motorcyclists. "Helmet use is the single most distinguished factor in people surviving motorcycle crashes," Gardner stated in the news release. "They depreciate the risk of head, brain and facial injury among motorcyclists of all ages and blast severities".
As summer approaches and many Americans quail to dust off their bikes, blades and assorted motorized vehicles, the nation's predicament unit doctors are trying to unqualified public attention toward the importance of wearing safety helmets to prevent serious brain injury. "People are riding bicycles, motorcycles and ATVs all-terrain vehicles more often at this ease of year," Dr Angela Gardner, president of the American College of Emergency Physicians (ACEP), said in a communication release. She stressed that bourgeoisie need to get in the habit of wearing a certified safety helmet, because it only takes one distressing crash to end a life or cause serious life-altering brain injuries.
Citing National Highway Transportation Safety Administration (NHTSA) statistics, the ACEP experts note that every year more than 300000 children are rushed to the difficulty worry as a result of injuries sustained while riding a bike. Wearing a helmet that meets Consumer Product Safety Commission standards could ease this figure by more than two-thirds, the combine suggests.
But children aren't the only ones who need to wear helmets. In fact, older riders merit for 75 percent of bicycle injury deaths, the ACEP noted. Among bicyclists of all ages, 540000 endeavour emergency care each year as a result of an accident, and 67000 of these patients allow head injuries. About 40 percent experience head trauma so acute that hospitalization is required.
A properly fitted helmet can prevent brain injury 90 percent of the time, according to the NHTSA, and if all bicyclists between the ages of 4 and 15 wore a helmet, between 39000 and 45000 proceed injuries could be prevented each year. With May designated as motorcycle refuge month, the ACEP is also highlighting the benefits of helmet use middle motorcyclists. "Helmet use is the single most distinguished factor in people surviving motorcycle crashes," Gardner stated in the news release. "They depreciate the risk of head, brain and facial injury among motorcyclists of all ages and blast severities".
Alleria Closely Associated To The Use Of Products From Fast Foods
Alleria Closely Associated To The Use Of Products From Fast Foods.
Kids who feed-bag rakishly food three or more times a week are disposed to to have more severe allergic reactions, a large new international study suggests. These comprise bouts of asthma, eczema and hay fever (rhinitis). And although the study doesn't confirm that those burgers, chicken snacks and fries cause these problems, the evidence of an association is compelling, researchers say. "The mull over adds to a growing body of evidence of the possible harms of fast foods," said work co-author Hywel Williams, a professor of dermato-epidemiology at the University of Nottingham, in England.
So "Whether the fact we have found is strong enough to recommend a reduction of fast food intake for those with allergies is a matter of debate". These discovery are important because this is the largest study to date on allergies in young people across the sphere and the findings are remarkably consistent globally for both boys and girls and regardless of family income. "If true, the findings have big consumers health implications given that these allergic disorders appear to be on the increase and because indecorously food is so popular".
However, Williams cautioned that fast food might not be causing these problems. "It could be due to other factors linked to behavior that we have not measured, or it could be due to biases that come to pass in studies that measure disease and ask about anterior food intake". In addition, this association between fast foods and severe allergies does not irresistibly mean that eating less fast food will reduce the severity of disease of asthma, hay fever or eczema (an itchy pelt disorder).
The report was published in the Jan 14, 2013 online point of Thorax. Williams and colleagues collected data on more than 319000 teens venerable 13 and 14 from 51 countries and more than 181000 kids aged 6 and 7 from 31 countries. All of the children were say of a single study on child asthma and allergies.
Kids and their parents were asked about whether they suffered from asthma or runny or blocked nose along with itchy and aqueous eyes and eczema. Participants also described in item what they ate during the week. Fast food was linked to those conditions in both older and younger children.
Kids who feed-bag rakishly food three or more times a week are disposed to to have more severe allergic reactions, a large new international study suggests. These comprise bouts of asthma, eczema and hay fever (rhinitis). And although the study doesn't confirm that those burgers, chicken snacks and fries cause these problems, the evidence of an association is compelling, researchers say. "The mull over adds to a growing body of evidence of the possible harms of fast foods," said work co-author Hywel Williams, a professor of dermato-epidemiology at the University of Nottingham, in England.
So "Whether the fact we have found is strong enough to recommend a reduction of fast food intake for those with allergies is a matter of debate". These discovery are important because this is the largest study to date on allergies in young people across the sphere and the findings are remarkably consistent globally for both boys and girls and regardless of family income. "If true, the findings have big consumers health implications given that these allergic disorders appear to be on the increase and because indecorously food is so popular".
However, Williams cautioned that fast food might not be causing these problems. "It could be due to other factors linked to behavior that we have not measured, or it could be due to biases that come to pass in studies that measure disease and ask about anterior food intake". In addition, this association between fast foods and severe allergies does not irresistibly mean that eating less fast food will reduce the severity of disease of asthma, hay fever or eczema (an itchy pelt disorder).
The report was published in the Jan 14, 2013 online point of Thorax. Williams and colleagues collected data on more than 319000 teens venerable 13 and 14 from 51 countries and more than 181000 kids aged 6 and 7 from 31 countries. All of the children were say of a single study on child asthma and allergies.
Kids and their parents were asked about whether they suffered from asthma or runny or blocked nose along with itchy and aqueous eyes and eczema. Participants also described in item what they ate during the week. Fast food was linked to those conditions in both older and younger children.
Some Medicines Purchased Via The Internet Can Be Dangerous
Some Medicines Purchased Via The Internet Can Be Dangerous.
Internet-based companies buy and sell them, men persist in to buy them and experts continue to apprise of the dangers of counterfeit drugs for erectile dysfunction. A new study, conducted in South Korea and slated for giving Monday at the American Urological Association annual meeting in San Francisco, finds that not only can these duplication drugs be contaminated, they may contain too much of the active ingredient or none at all. The drugs could especially be menacing for men with hypertension or heart disease, the study found.
The message? Stay away from non-prescription erectile dysfunction (ED) drugs, the experts say. "There are lots of rip-offs," said Dr John Morley, cicerone of geriatrics and acting chief of endocrinology at Saint Louis University. "There's still a lot of deposition that many of the things you buy off the Internet without going through a regular dispensary might appear cheaper or better but they're usually not and they usually don't work".
Drugs known as phosphodiesterase type 5 inhibitors (PDE5Is) are worn widely by men with erectile dysfunction - and sometimes by those without the condition. Perhaps the best known of the caste are sildenafil (Viagra) and tadalafil (Cialis). Since it was developed in 1998, the demand for these and similar products - legitimate or not - has mushroomed.
Internet-based companies buy and sell them, men persist in to buy them and experts continue to apprise of the dangers of counterfeit drugs for erectile dysfunction. A new study, conducted in South Korea and slated for giving Monday at the American Urological Association annual meeting in San Francisco, finds that not only can these duplication drugs be contaminated, they may contain too much of the active ingredient or none at all. The drugs could especially be menacing for men with hypertension or heart disease, the study found.
The message? Stay away from non-prescription erectile dysfunction (ED) drugs, the experts say. "There are lots of rip-offs," said Dr John Morley, cicerone of geriatrics and acting chief of endocrinology at Saint Louis University. "There's still a lot of deposition that many of the things you buy off the Internet without going through a regular dispensary might appear cheaper or better but they're usually not and they usually don't work".
Drugs known as phosphodiesterase type 5 inhibitors (PDE5Is) are worn widely by men with erectile dysfunction - and sometimes by those without the condition. Perhaps the best known of the caste are sildenafil (Viagra) and tadalafil (Cialis). Since it was developed in 1998, the demand for these and similar products - legitimate or not - has mushroomed.
Heart Risk For Elderly People Increases When Sleep Apnea
Heart Risk For Elderly People Increases When Sleep Apnea.
The snoring and breathing disturbances of beauty sleep apnea may be more than just a nuisance, with a late study linking the get to higher risks for heart failure and heart disease in middle-aged and older men. However, the deliberate over found no correlation between sleep apnea and coronary heart disease in women, or in men older than 70.
And "The vital here is that there is a lot of undiagnosed sleep apnea, and that, at least in men, it is associated with the phenomenon of coronary heart disease and heart failure. Only about 10 percent of catch forty winks apnea cases are diagnosed," said Dr Daniel Gottlieb, associate professor of medicine, Boston University School of Medicine. Gottlieb esteemed that while the jump in heart gamble was noteworthy, it was not as large as that seen in previous clinic-based studies of sleep apnea because the participants were drawn from a filthy community-based population.
According to background information in the study, sleep apnea sufferers awaken feverishly during the night struggling to breathe, often experiencing a shot of blood pressure- raising adrenaline. Most often, they go fist back to sleep, unaware of what happened. But the awakenings are repeated, sometimes up to 30 times an hour, depriving the sufferer of dynamic oxygen and sound sleep.
The research is published online July 12 in Circulation. In the study, almost 2000 men and about 2500 women - all released of verve problems at the beginning of the research - were recorded as they slept using polysomnograms, which premeditated the presence and severity of sleep apnea as calibrated on the Apnea-Hypopnea Index. About half had no symptoms of zizz apnea, the team found, while half had mild, moderate or severe symptoms.
Participants were then contacted at various times from 1998 to the irrevocable follow-up in April 2006. During that time, 473 cardiac events occurred, including 185 boldness attacks, 212 heart bypass operations, and 76 deaths. There were also 308 cases of centre failure; of these 144 people also had a nucleus attack.
The snoring and breathing disturbances of beauty sleep apnea may be more than just a nuisance, with a late study linking the get to higher risks for heart failure and heart disease in middle-aged and older men. However, the deliberate over found no correlation between sleep apnea and coronary heart disease in women, or in men older than 70.
And "The vital here is that there is a lot of undiagnosed sleep apnea, and that, at least in men, it is associated with the phenomenon of coronary heart disease and heart failure. Only about 10 percent of catch forty winks apnea cases are diagnosed," said Dr Daniel Gottlieb, associate professor of medicine, Boston University School of Medicine. Gottlieb esteemed that while the jump in heart gamble was noteworthy, it was not as large as that seen in previous clinic-based studies of sleep apnea because the participants were drawn from a filthy community-based population.
According to background information in the study, sleep apnea sufferers awaken feverishly during the night struggling to breathe, often experiencing a shot of blood pressure- raising adrenaline. Most often, they go fist back to sleep, unaware of what happened. But the awakenings are repeated, sometimes up to 30 times an hour, depriving the sufferer of dynamic oxygen and sound sleep.
The research is published online July 12 in Circulation. In the study, almost 2000 men and about 2500 women - all released of verve problems at the beginning of the research - were recorded as they slept using polysomnograms, which premeditated the presence and severity of sleep apnea as calibrated on the Apnea-Hypopnea Index. About half had no symptoms of zizz apnea, the team found, while half had mild, moderate or severe symptoms.
Participants were then contacted at various times from 1998 to the irrevocable follow-up in April 2006. During that time, 473 cardiac events occurred, including 185 boldness attacks, 212 heart bypass operations, and 76 deaths. There were also 308 cases of centre failure; of these 144 people also had a nucleus attack.
Saturday 11 January 2020
The Relationship Between Asthma And Chronic Nasal Congestion
The Relationship Between Asthma And Chronic Nasal Congestion.
A redone Swedish office shows that severe asthma seems to be more common than previously believed. It also reports that those afflicted by it have a higher mastery of blocked or runny noses, a possible initials that physicians should pay more attention to nasal congestion and similar issues. In the study, researchers surveyed 30000 woman in the street from the west of Sweden and asked about their health, including whether they had physician-diagnosed asthma, took asthma medication, and if so, what lenient of symptoms they experienced.
And "This is the first patch that the prevalence of severe asthma has been estimated in a population study, documenting that approximately 2 percent of the citizens in the West Sweden is showing signs of severe asthma," study co-author Jan Lotvall, professor at Sahlgrenska Academy's Krefting Research Center, said in a newsflash release from the University of Gothenburg. "This argues that more unembroidered forms of asthma are far more common than previously believed, and that trim care professionals should pay extra attention to patients with such symptoms".
A redone Swedish office shows that severe asthma seems to be more common than previously believed. It also reports that those afflicted by it have a higher mastery of blocked or runny noses, a possible initials that physicians should pay more attention to nasal congestion and similar issues. In the study, researchers surveyed 30000 woman in the street from the west of Sweden and asked about their health, including whether they had physician-diagnosed asthma, took asthma medication, and if so, what lenient of symptoms they experienced.
And "This is the first patch that the prevalence of severe asthma has been estimated in a population study, documenting that approximately 2 percent of the citizens in the West Sweden is showing signs of severe asthma," study co-author Jan Lotvall, professor at Sahlgrenska Academy's Krefting Research Center, said in a newsflash release from the University of Gothenburg. "This argues that more unembroidered forms of asthma are far more common than previously believed, and that trim care professionals should pay extra attention to patients with such symptoms".
Eating The Correct Ratio Of Omega-3 DHA And EPA Can Help Alleviate Depression
Eating The Correct Ratio Of Omega-3 DHA And EPA Can Help Alleviate Depression.
Omega-3 fatty acids may ease alleviate indentation but only when a unusual type of fatty acid called DHA is used in the right ratio with another fatty acid known as EPA, a redesigned study suggests. The researchers analyzed the results of some 15 above-named controlled clinical trials on the use of omega-3s - commonly found in oily fish or in fish unguent supplements - to treat depressed people. They found that when used by itself, DHA (docosahexaenoic acid) only did not seem to offer any benefit.
However, DHA combined with a rather high portion of EPA (eicosapentenoic acid) did improve depressive symptoms. "Preparations with some EPA had some consistent antidepressant effects, while preparations of unmixed DHA had no antidepressant effects," said lead study architect Dr John Davis, a professor of psychiatry at the University of Illinois at Chicago. "I don't of we can prove it beyond a shadow of a doubt, but there is now evidence from a number of double-blind studies that suggest mixed DHA/EPA has antidepressant properties, whether by itself or given along with unwritten antidepressants".
The study, funded by the US National Institutes of Health, was designed as a meta-analysis, in which researchers merge the results of multiple prior studies. The findings were slated for donation Thursday at the American College of Neuropsychopharmacology meeting in Miami.
Davis noted the next stage should be to test the anti-depressant effect of the omega-3 fatty acid combination in a large population to affirm a dose range. Prior research on the effectiveness of omega-3 fattys acids against depression has been mixed, with one new randomized, placebo-controlled clinical trial in the Journal of the American Medical Association, for example, concluding that taking 800 milligrams of DHA everyday did not help ward off depression in pregnant women.
Omega-3 fatty acids may ease alleviate indentation but only when a unusual type of fatty acid called DHA is used in the right ratio with another fatty acid known as EPA, a redesigned study suggests. The researchers analyzed the results of some 15 above-named controlled clinical trials on the use of omega-3s - commonly found in oily fish or in fish unguent supplements - to treat depressed people. They found that when used by itself, DHA (docosahexaenoic acid) only did not seem to offer any benefit.
However, DHA combined with a rather high portion of EPA (eicosapentenoic acid) did improve depressive symptoms. "Preparations with some EPA had some consistent antidepressant effects, while preparations of unmixed DHA had no antidepressant effects," said lead study architect Dr John Davis, a professor of psychiatry at the University of Illinois at Chicago. "I don't of we can prove it beyond a shadow of a doubt, but there is now evidence from a number of double-blind studies that suggest mixed DHA/EPA has antidepressant properties, whether by itself or given along with unwritten antidepressants".
The study, funded by the US National Institutes of Health, was designed as a meta-analysis, in which researchers merge the results of multiple prior studies. The findings were slated for donation Thursday at the American College of Neuropsychopharmacology meeting in Miami.
Davis noted the next stage should be to test the anti-depressant effect of the omega-3 fatty acid combination in a large population to affirm a dose range. Prior research on the effectiveness of omega-3 fattys acids against depression has been mixed, with one new randomized, placebo-controlled clinical trial in the Journal of the American Medical Association, for example, concluding that taking 800 milligrams of DHA everyday did not help ward off depression in pregnant women.
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